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Infections Post Transplant

Tuberculosis among allogeneic bone marrow transplant recipients in India

Bone Marrow Transplantation volume 27, pages 973–975 (2001)Cite this article

Abstract

Allogeneic bone marrow transplant recipients have severe impairment of cell-mediated immunity and hence a higher incidence of mycobacterial infections might be expected in regions where tuberculosis is common. We reviewed the case records of 217 patients who underwent allogeneic bone marrow transplantation during the period 1986–1999 at our center in India. Mycobacterial infections were diagnosed in three patients (1.38%). All patients presented with extrapulmonary disease. Two patients had disseminated tuberculosis with one of these being diagnosed on autopsy studies. The third patient had tuberculosis involving the cervical lymph node and dorsal spine. Two patients treated with antituberculous therapy are well. Infection with Mycobacterium tuberculosis is not a common problem in allogeneic bone marrow recipients even in an endemic area, but when it occurs, it is usually disseminated with predominantly extrapulmonary involvement. Bone Marrow Transplantation (2001) 27, 973–975.

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Authors and Affiliations

  1. Department of Hematology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India

    B George, V Mathews, A Srivastava & M Chandy

  2. Department of Pathology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India

    V Srivastava

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  1. B George
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  2. V Mathews
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  3. V Srivastava
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  4. A Srivastava
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  5. M Chandy
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George, B., Mathews, V., Srivastava, V. et al. Tuberculosis among allogeneic bone marrow transplant recipients in India. Bone Marrow Transplant 27, 973–975 (2001). https://doi.org/10.1038/sj.bmt.1702993

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