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The effect of treatment on health-related quality of life in patients with hypertension and renal artery stenosis

Journal of Human Hypertension volume 19, pages 467–470 (2005)Cite this article

Abstract

The quality of life in patients with hypertension is considered to be impaired mainly by side effects of antihypertensive drug therapy. Since balloon angioplasty for renal artery stenosis has a medication-sparing effect, it may lead to an improvement in quality of life. The objective of the study is to compare the effect of antihypertensive drug therapy and balloon angioplasty on quality of life in patients with hypertension and renal artery stenosis. We compared the quality of life in 56 patients randomised to balloon angioplasty to that in 50 patients randomised to antihypertensive drug therapy after 3 and 12 months of follow-up. Quality of life was measured using a questionnaire on physical symptoms associated with hypertension and antihypertensive drugs, and two generic health questionnaires (MOS Survey and EuroQol instrument). After follow-up, the patients who underwent angioplasty used less antihypertensive drugs than the patients who were treated with antihypertensive drugs only (mean±s.d., 1.9±0.9 vs 2.5±1.0 drugs after 3 months, P=0.002). They reported similar physical complaints, however, and a similar quality of life. The results after 12 months of follow-up were the same. In conclusion, for patients with hypertension and renal artery stenosis, the decrease in antihypertensive medication after intervention is too small to lead to a detectable improvement in quality of life.

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Acknowledgements

As part of a larger study, this research project was financially supported by the Dutch Health Council (grant OG92-031).

Potential conflicts of interest: None.

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Authors and Affiliations

  1. Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

    P Krijnen & J D F Habbema

  2. Department of Nephrology, Utrecht Medical Center, Utrecht, The Netherlands

    B C van Jaarsveld

  3. Dianet Dialysis Centers, Utrecht, The Netherlands

    B C van Jaarsveld

  4. Department of Radiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

    M G M Hunink

  5. Department of Epidemiology & Biostatistics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

    M G M Hunink

Authors
  1. P Krijnen
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  2. B C van Jaarsveld
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  3. M G M Hunink
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  4. J D F Habbema
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Correspondence to P Krijnen.

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Krijnen, P., van Jaarsveld, B., Hunink, M. et al. The effect of treatment on health-related quality of life in patients with hypertension and renal artery stenosis. J Hum Hypertens 19, 467–470 (2005). https://doi.org/10.1038/sj.jhh.1001847

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  • DOI: https://doi.org/10.1038/sj.jhh.1001847

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