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Erythroleukaemia and RAEB-t: a same disease?

Leukemia volume 18, pages 888–890 (2004)Cite this article

TO THE EDITOR

Erythroleukaemia are divided into several entities and are subject of controversies since their initial definition by Di Guglielmo in 1917.1 In 1976, the FAB classification considered erythroleukaemia as a proliferation of erythroblasts >50% and a proliferation of blasts >30% without taking into account the predominance of erythroblasts, which rendered the diagnosis rare since the proportion of 30% of blasts was rarely reached. The FAB classification revised its AML6 diagnosis criteria in 1985: after eliminating the erythroid component (that represents at least 50% of the marrow), the proportion of blasts was counted in reference to the remaining population. So AML6 was defined as a proliferation of erythroblasts superior to 50% and of myeloblasts superior to 30%, besides the erythroblasts.2

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Authors and Affiliations

  1. Laboratoire d'hématologie, Hôpital Cochin, AP-HP, Paris, France

    S Park, F Picard, M Guesnu & F Dreyfus

  2. Service d'hématologie, Hôpital Cochin, AP-HP, Paris, France

    S Park & F Dreyfus

  3. Laboratoire d'hématologie, HôpitalPitié-Salpétrière, AP-HP, France

    K Maloum

  4. Service d'hématologie, HôpitalPitié-Salpétrière, AP-HP, France

    V Leblond

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  1. S Park
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Correspondence to S Park.

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Park, S., Picard, F., Guesnu, M. et al. Erythroleukaemia and RAEB-t: a same disease?. Leukemia 18, 888–890 (2004). https://doi.org/10.1038/sj.leu.2403316

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