You are here

  • Home
  • Archive
  • Volume 21, Issue 8
  • Radical Vaginal Trachelectomy (RVT) Combined With Laparoscopic Lymphadenectomy: Prospective Study of 225 Patients With Early-Stage Cervical Cancer

Article Text

Article menu
Download PDFPDF
Cervical Cancer
Radical Vaginal Trachelectomy (RVT) Combined With Laparoscopic Lymphadenectomy: Prospective Study of 225 Patients With Early-Stage Cervical Cancer
  1. Malgorzata Lanowska, MD*,
  2. Mandy Mangler, MD*,
  3. Annabel Spek, Cand Med*,
  4. Ulrike Grittner, PhD†,
  5. Kati Hasenbein, MD*,
  6. Vito Chiantera, MD*,
  7. Hermann Hertel, MD‡,
  8. Achim Schneider, MD, MPH*,
  9. Christhardt Köhler, MD* and
  10. Dorothee Speiser, MD*
  1. *Department of Gynecology, Charité University Medicine, Berlin, Germany;
  2. †Department of Biometrics and Clinical Epidemiology, Charité University Medicine, Berlin, Germany; and
  3. ‡Department of Gynecology, Medical School Hannover, Hannover, Germany.
  1. Address correspondence and reprint requests to Malgorzata Lanowska, MD, Department of Gynecology, Charite˙ Universitätsmedizin Berlin, Campus Mitte and Benjamin Franklin, Charitéplatz 1, D-10117 Berlin, Germany. E-mail: malgorzata.lanowska{at}charite.de.

Abstract

Objective: The aim of the study was to prove the surgical and oncological safety of radical vaginal trachelectomy (RVT) and laparoscopic lymphadenectomy for patients with early-stage cervical cancer who are seeking parenthood.

Methods: A database of 225 patients with early-stage cervical cancer and intention to treat by RVT after laparoscopic lymphadenectomy was prospectively maintained. A total of 212 patients were treated according to the protocol. The procedure was preformed in a standardized manner, and life table analysis was applied.

Results: In the cohort of patients treated according to protocol, 8 recurrences occurred and 4 patients died from recurrence. The median follow-up time was 37 months (range, 0-171 months). The 5-year recurrence-free and overall survival was 94.4% and 97.4%, respectively. Perioperative and short-term postoperative complications were rare (2.8% and 7.5%, respectively). No severe long-term complications occurred.

Conclusions: Radical vaginal trachelectomy combined with laparoscopic lymphadenectomy is a safe method for treatment of patients with early-stage cervical cancer who are seeking parenthood.

  • Early-stage cervical cancer
  • Radical vaginal trachelectomy
  • Fertility-preserving surgery
  • Laparoscopic lymphadenectomy

https://doi.org/10.1097/IGC.0b013e3182216aa7

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Footnotes

    • There were no sources of support for this work.

    • The authors declare that there are no conflicts of interest.