Epigenetics, Histone H3 Variants, and the Inheritance of Chromatin States

  1. S. HENIKOFF,
  2. E. MCKITTRICK, and
  3. K. AHMAD
  1. *Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109;Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115

This extract was created in the absence of an abstract.

Excerpt

The 68th Cold Spring Harbor Symposium celebratedan extraordinary accomplishment in molecular biology:determination of the human genomic sequence. Thislandmark achievement highlights the rapid and steadyprogress that has occurred over the past 50 years beginning with the Watson–Crick model of DNA and culminating in the nearly complete specification of our geneticinheritance. In contrast, the 69th Symposium deals with atopic, epigenetics, that was already 25 years old at thetime of the Watson–Crick model, and yet the salient features of epigenetic phenomena have remained almost asmysterious now as when they were first described...

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