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HEC-1 cells

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Abstract

HEC-1 cell line was the first in vitro cell line of a human endometrial adenocarcinoma which enabled us to perform research work on the endometrium and endometrial carcinoma at a simplified cellular system, contributing cell and molecular biological studies on endometrial carcinoma Once a cell line is established, it provides a stable experimental system that facilitates and progresses in the study of the tissues and/or neoplasias from which they are derived. In this article we report how HEC-1 cells have been established and cleared the proposed requirements to characterize the established cell line. Also to show the usefulness of the cell line for research work, once it was established, we illustrate these concepts by recalling results obtained with HEC-1 cells and reviewing the literature on what has been achieved by using these cells.

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Authors and Affiliations

  1. Department of Clinical Cytology Graduate School of Medical Sciences, Kitasato University, 1-151 Kitasato Sagamihara, 228-8555, Kanagawa, Japan

    Hiroyuki Kuramoto

  2. Tissue Culture Center, School of Medicine, Kitasato University, Japan

    Mieko Hamano

  3. Department of Obstetrics and Gynecology, School of Medicine, Kitasato University, Japan

    Manami Imai

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  1. Hiroyuki Kuramoto
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  2. Mieko Hamano
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  3. Manami Imai
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Correspondence to Hiroyuki Kuramoto.

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Kuramoto, H., Hamano, M. & Imai, M. HEC-1 cells. Hum Cell 15, 81–95 (2002). https://doi.org/10.1111/j.1749-0774.2002.tb00103.x

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