Laser-assisted cartilage reshaping: in vitro and in vivo animal studies

Zhi Wang; Michail M. Pankratov; Donald F. Perrault Jr.; Stanley M. Shapshay M.D.

doi:10.1117/12.209113

12 May 1995 Laser-assisted cartilage reshaping: in vitro and in vivo animal studies

Zhi Wang, Michail M. Pankratov, Donald F. Perrault Jr., Stanley M. Shapshay M.D.

Proceedings Volume 2395, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems V; (1995) https://doi.org/10.1117/12.209113
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

Correction of cartilaginous defects in the head and neck area remains a challenge for the surgeon. This study investigated a new technique for laser-assisted cartilage reshaping. The pulsed 1.44 micrometers Nd:YAG laser was used in vitro and in vivo experiments to irradiate cartilage to change it's shape without carbonization or vaporization of tissue. Two watts of average power in non contact manner was used to irradiate and reshape the cartilage. The extracted reshaped cartilage specimens underwent testing of elastic force with a computer assisted measurement system that recorded the changes in elastic force in the specimens from 1 hr to 11 days post-irradiation. An animal model of defective tracheal cartilage (collapsed tracheal wall) was created, allowed to heal for 6 weeks and then corrected endoscopically with the laser-assisted technique. The results of the in vitro and in vivo investigations demonstrated that it was possible to alter the cartilage and that cartilage would retain its new shape. The clinical significance of the technique is evident and warrants further animal studies and clinical trials.

Citation Download Citation

Zhi Wang, Michail M. Pankratov, Donald F. Perrault Jr., and Stanley M. Shapshay M.D. "Laser-assisted cartilage reshaping: in vitro and in vivo animal studies", Proc. SPIE 2395, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems V, (12 May 1995); https://doi.org/10.1117/12.209113

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