Quantitative study of hypoxia stress in piglet brain by IQ phase modulation oximetry

Hong Yan Ma; Q. Xu; J. R. Bellesteros; Vasilis Ntziachristos; Qingqi Zhang; Britton Chance

doi:10.1117/12.356793

15 July 1999 Quantitative study of hypoxia stress in piglet brain by IQ phase modulation oximetry

Hong Yan Ma, Q. Xu, J. R. Bellesteros, Vasilis Ntziachristos, Qingqi Zhang, Britton Chance

Proceedings Volume 3597, Optical Tomography and Spectroscopy of Tissue III; (1999) https://doi.org/10.1117/12.356793
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

The quantification of tissue hemoglobin oxygen saturation has great clinical significance either to predict per-term baby brain damage or other dysfunction due to abnormal hemoglobin saturation level. From our experiments we find out that the background absorption can affect the accuracy in calculating saturation of hemoglobin either the range or the value. Practically it is difficult to get the absolute value of background absorption so we try to use empirical approach to obtain this value. Our goal is to investigate the transferability of this empirical value from a small ground of population to general population and from piglets to man.

Citation Download Citation

Hong Yan Ma, Q. Xu, J. R. Bellesteros, Vasilis Ntziachristos, Qingqi Zhang, and Britton Chance "Quantitative study of hypoxia stress in piglet brain by IQ phase modulation oximetry", Proc. SPIE 3597, Optical Tomography and Spectroscopy of Tissue III, (15 July 1999); https://doi.org/10.1117/12.356793

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