Article Text
Hypothesis
Is progressive osteoarthritis an atheromatous vascular disease?
Abstract
Growing evidence from epidemiological studies suggests that osteoarthritis (OA) is linked to atheromatous vascular disease. This hypothesis article proposes that OA, or at least OA structural progression, may be an atheromatous vascular disease of subchondral bone. Further epidemiological studies, imaging investigations of relevant blood vessels, and trials of the effects of statins on the prevention and treatment of OA are needed to examine this hypothesis.
- MRI, magnetic resonance imaging
- NSAIDs, non-steroidal anti-inflammatory drugs
- OA, osteoarthritis
- osteoarthritis
- atheromatous vascular disease
- subchondral bone