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Blue Dye Injection in the Arm in Order to Conserve the Lymphatic Drainage of the Arm in Breast Cancer Patients Requiring an Axillary Dissection

  • Breast Oncology
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

Abstract

Background

Despite the widespread use of the sentinel lymph node biopsy technique, many patients with invasive breast cancer still undergo an axillary lymph node dissection and are at risk of arm lymphedema. With the new awareness of lymphatic spread in the axillary nodes, it should be possible to define a new surgical approach between sentinel lymph node biopsy and complete axillary dissection, a procedure preserving specifically lymph nodes in relation to the arm.

Methods

Twenty-one patients with an operable breast cancer requiring an axillary dissection underwent surgery with an attempt to separate nodes related to the breast from specific nodes related to the arm. After an injection of blue dye in the arm, the surgeon performed the axillary dissection trying to identify blue nodes and ducts in order to preserve lymphatic arm drainage (LAD). If the blue nodes were located in the normal axillary dissection, they were removed separately.

Results

In 15 of 21 patients (71%), blue nodes in relation with LAD were identified. In 10 (47%) patients, it was possible to dissect the LAD with the preservation lymphatic ducts. In 10 patients, the LAD nodes were removed: none of them contained metastases, despite the fact that the non-LAD axillary nodes contained metastases in 7 of 10 cases.

Conclusions

Identifying the LAD with blue dye injection in the arm is possible. A subsequent study can now begin to determine if this procedure is safe for patients and able to prevent lymphedema of the arm.

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Acknowlegment

I thank particularly Prof Charles E Cox and Dr Charles Elboim for their contribution to this article.

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Authors and Affiliations

  1. Department of Gynecologic and Oncologic Surgery, Hôpital Européen Georges Pompidou, Paris, France

    Claude Nos MD, Benedicte Lesieur MD, Krishna B. Clough MD & Fabrice Lecuru PhD

Authors
  1. Claude Nos MD
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  2. Benedicte Lesieur MD
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  3. Krishna B. Clough MD
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  4. Fabrice Lecuru PhD
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Correspondence to Claude Nos MD.

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Nos, C., Lesieur, B., Clough, K.B. et al. Blue Dye Injection in the Arm in Order to Conserve the Lymphatic Drainage of the Arm in Breast Cancer Patients Requiring an Axillary Dissection. Ann Surg Oncol 14, 2490–2496 (2007). https://doi.org/10.1245/s10434-007-9450-4

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  • DOI: https://doi.org/10.1245/s10434-007-9450-4

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