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Licensed Unlicensed Requires Authentication Published by De Gruyter August 26, 2015

Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation syndrome and celiac disease in a 13-year-old girl: further evidence for autoimmunity?

  • Ayse Pinar Cemeroglu EMAIL logo , Donna S. Eng , Laura A. Most , Carrissa M. Stalsonburg and Lora Kleis

Abstract

Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation (ROHHAD) syndrome is a rare and potentially lethal disorder. The etiology is unclear but paraneoplastic syndrome and autoimmunity secondary to neural crest tumors have been considered, even in patients without any detectable tumor due to their tendency for spontaneous remission. We are presenting a 13-year-old girl with ROHHAD syndrome and celiac disease, which may suggest further evidence for immune-mediated etiology in the pathogenesis of ROHHAD syndrome.


Corresponding author: Ayse Pinar Cemeroglu, MD, Pediatric Endocrinologist, Associate Professor of Pediatrics, Michigan State University, Spectrum Health Medical Group, Helen DeVos Children’s Hospital, 230 Michigan Street NE, Suite 101, MC 77, Grand Rapids, Michigan 49503, USA, Phone: +(616) 391 3933, Fax: +(616) 391 6240, E-mail: ; and Michigan State University, Grand Rapids Campus, Grand Rapids, MI, USA

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Received: 2015-3-23
Accepted: 2015-7-24
Published Online: 2015-8-26
Published in Print: 2016-1-1

©2016 by De Gruyter

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