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BY-NC-ND 4.0 license Open Access Published by De Gruyter November 13, 2018

Periodontal, metabolic, and cardiovascular disease: Exploring the role of inflammation and mental health

  • Hina Makkar , Mark A. Reynolds , Abhishek Wadhawan , Aline Dagdag , Anwar T. Merchant and Teodor T. Postolache EMAIL logo
From the journal Pteridines

Abstract

Previous evidence connects periodontal disease, a modifiable condition affecting a majority of Americans, with metabolic and cardiovascular morbidity and mortality. This review focuses on the likely mediation of these associations by immune activation and their potential interactions with mental illness. Future longitudinal, and ideally interventional studies, should focus on reciprocal interactions and cascading effects, as well as points for effective preventative and therapeutic interventions across diagnostic domains to reduce morbidity, mortality and improve quality of life.

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Received: 2018-09-13
Accepted: 2018-10-10
Published Online: 2018-11-13
Published in Print: 2018-11-01

© 2018 Teodor T. Postolache, et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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