Abstract
Viral infections are some of the most frequent complications in patients with hematologic malignancies are viral infections. Infections caused by cytomegalovirus, herpes simplex virus, varicella zoster virus, hepatitis B virus and influenza virus are associated with high morbidity and mortality in this vulnerable population. Fortunately, a growing number of antiviral medications and vaccines are allowing for more effective prophylaxis against these pathogens. This article reviews the epidemiology and prophylactic strategies available for these opportunistic viral pathogens.
Keywords: Cytomegalovirus, herpes simplex virus, varicella zoster virus, influenza virus, hepatitis B virus, hematologic malignancy, anti-viral agents, vaccines, prophylaxis, T-cell dysfunction, lymphoid derived leukemia, mye-loid derived leukemia, chronic lymphocytic leukemia, fludarabine, monoclonal antibodies, pneumonitis, alemtuzumab, oral acyclovir
Infectious Disorders - Drug Targets
Title: Epidemiology and Prevention of Viral Infections in Patients with Hematologic Malignancies
Volume: 11 Issue: 1
Author(s): Michael Angarone
Affiliation:
Keywords: Cytomegalovirus, herpes simplex virus, varicella zoster virus, influenza virus, hepatitis B virus, hematologic malignancy, anti-viral agents, vaccines, prophylaxis, T-cell dysfunction, lymphoid derived leukemia, mye-loid derived leukemia, chronic lymphocytic leukemia, fludarabine, monoclonal antibodies, pneumonitis, alemtuzumab, oral acyclovir
Abstract: Viral infections are some of the most frequent complications in patients with hematologic malignancies are viral infections. Infections caused by cytomegalovirus, herpes simplex virus, varicella zoster virus, hepatitis B virus and influenza virus are associated with high morbidity and mortality in this vulnerable population. Fortunately, a growing number of antiviral medications and vaccines are allowing for more effective prophylaxis against these pathogens. This article reviews the epidemiology and prophylactic strategies available for these opportunistic viral pathogens.
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Cite this article as:
Angarone Michael, Epidemiology and Prevention of Viral Infections in Patients with Hematologic Malignancies, Infectious Disorders - Drug Targets 2011; 11 (1) . https://dx.doi.org/10.2174/187152611794407773
DOI https://dx.doi.org/10.2174/187152611794407773 |
Print ISSN 1871-5265 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3989 |
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