Impact of Exposure to Ambient Fine Particulate Matter Pollution on Adults with Knee Osteoarthritis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Data on Outpatient Visits for Knee Osteoarthritis
2.2. Environmental Data
2.3. Statistical Analysis
3. Results
3.1. Demographic Information
3.2. Daily Values of PM2.5, Outpatient Visits for Knee Osteoarthritis, Temperature, and Humidity
3.3. Changes in the Number of Outpatient Visits According to PM2.5 Concentration
3.4. Influence of Age, Gender, and Season on Changes in the Number of Outpatient Visits
3.5. Reliability of the Data
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Variable | All Year | Cool Season | Warm Season |
---|---|---|---|
Outpatient visits | 9,797,446 | 5,865,689 | 3,931,757 |
Sex | |||
Male(%) | 3,565,162 (36.39) | 2,140,860 (36.50) | 1,424,302 (36.23) |
Female(%) | 6,232,284 (63.61) | 3,724,829 (63.50) | 2,507,455 (63.77) |
Age(year) | |||
18–64(%) | 6,254,770 (63.84) | 3,733,856 (63.66) | 2,520,914 (64.12) |
≥65(%) | 3,542,676 (36.16) | 2,131,833 (36.34) | 1,410,843 (35.88) |
Variable | Mean ± SD | Minimum | Percentile | Maximum | IQR | ||
---|---|---|---|---|---|---|---|
25th | 50th | 75th | |||||
Daily outpatient visits | 3354 ± 3700 | 108 | 324 | 2406 | 4684 | 30,125 | 4360 |
PM2.5(μg/m3) | 86.8 ± 74.3 | 1.0 | 33.3 | 66.5 | 115.0 | 537.3 | 81.7 |
Daily outpatient visits during the cool season | 3457 ± 4074 | 108 | 116 | 2324 | 4960 | 30,125 | 4844 |
Daily outpatient visits during the warm season | 3212 ± 3103 | 133 | 942 | 2492 | 4287 | 14,596 | 3345 |
Temperature (℃) | 14.6 ± 11.3 | −14.3 | 2.6 | 15.1 | 24.0 | 34.5 | 21.4 |
Relative humidity (%) | 51.8 ± 20.2 | 8 | 35 | 52 | 68 | 88 | 33 |
Lag Day | Percentage Change | 95% Confidence Interval | p |
---|---|---|---|
Lag 0 day | 1.20 | 1.20–1.21 | <0.001 |
Lag 1 day | 0.61 | 0.61–0.62 | <0.001 |
Lag 2 day | 0.59 | 0.59–0.59 | <0.001 |
Lag 3 day | 0.54 | 0.54–0.55 | <0.001 |
Lag 0–1 days | 1.22 | 1.21–1.22 | <0.001 |
Lag 0–2 days | 1.32 | 1.31–1.32 | <0.001 |
Lag 0–3 days | 1.41 | 1.40–1.41 | <0.001 |
Subgroups | Percentage Change | 95% Confidence Interval | ap |
---|---|---|---|
Sex | |||
Male | 1.36 | 1.35–1.37 | <0.001 |
Female | 1.41 | 1.40–1.42 | <0.001 |
Age(year) | |||
18–64 | 1.28 | 1.28–1.29 | <0.001 |
≥65 | 1.59 | 1.58–1.60 | <0.001 |
Season | |||
Cool | 0.75 | 0.74–0.76 | <0.001 |
Warm | 2.76 | 2.75–2.78 | <0.001 |
Variable | df | Percentage Change | 95% Confidence Interval | p Value |
---|---|---|---|---|
Calendar time | 6 | 1.40 | 1.39–1.40 | <0.001 |
7 * | 1.41 | 1.40–1.41 | <0.001 | |
8 | 1.25 | 1.24–1.25 | <0.001 | |
9 | 1.25 | 1.24–1.26 | <0.001 | |
Temperature | 5 | 1.44 | 1.43–1.45 | <0.001 |
6 * | 1.41 | 1.40–1.41 | <0.001 | |
7 | 1.33 | 1.32–1.33 | <0.001 | |
8 | 1.37 | 1.36–1.37 | <0.001 | |
Relative humidity | 3 * | 1.41 | 1.40–1.41 | <0.001 |
4 | 1.42 | 1.41–1.42 | <0.001 | |
5 | 1.42 | 1.41–1.42 | <0.001 | |
6 | 1.42 | 1.41–1.43 | <0.001 |
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Chen, H.; Wu, J.; Wang, M.; Wang, S.; Wang, J.; Yu, H.; Hu, Y.; Shang, S. Impact of Exposure to Ambient Fine Particulate Matter Pollution on Adults with Knee Osteoarthritis. Int. J. Environ. Res. Public Health 2021, 18, 9644. https://doi.org/10.3390/ijerph18189644
Chen H, Wu J, Wang M, Wang S, Wang J, Yu H, Hu Y, Shang S. Impact of Exposure to Ambient Fine Particulate Matter Pollution on Adults with Knee Osteoarthritis. International Journal of Environmental Research and Public Health. 2021; 18(18):9644. https://doi.org/10.3390/ijerph18189644
Chicago/Turabian StyleChen, Hongbo, Junhui Wu, Mengying Wang, Siyue Wang, Jiating Wang, Huan Yu, Yonghua Hu, and Shaomei Shang. 2021. "Impact of Exposure to Ambient Fine Particulate Matter Pollution on Adults with Knee Osteoarthritis" International Journal of Environmental Research and Public Health 18, no. 18: 9644. https://doi.org/10.3390/ijerph18189644