Association between Toxoplasma gondii Infection and Type-1 Diabetes Mellitus: A Systematic Review and Meta-Analysis
Abstract
:1. Introduction
2. Methods
2.1. Information Source and Search Strategy
2.2. Article Selection Criteria
2.3. Data Extraction
2.4. Data Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
References
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Author, Ref. | T1DM Group | Control Group | p Value | ||||||
---|---|---|---|---|---|---|---|---|---|
Cases, n | Female | Mean Age, Years | T. gondii Seropositive, n | Cases, n | Female | Mean Age, Years | T. gondii. Seropositive, n | ||
Krause et al. [22] | 57 | 57.9% | 16 | 3 | 140 | - | - | 56 | 0.001 |
Xia and Huang [23] | 337 | 37.7% | 40 | 61 | 337 | - | - | 15 | <0.01 |
Soltani et al. [9] | 36 | 47.2% | - | 25 | 50 | 50% | - | 17 | 0.001 |
Li et al. [24] | 400 | 48.2% | - | 66 | 400 | 44.8% | - | 46 | 0.042 |
Nassief Beshay et al. [14] | 44 | 59.1% | 25 | 38 | 30 | 56.7% | 29 | 18 | 0.027 |
Asgari et al. [8] | 91 | 59.3% | - | 26 | 91 | 63.7% | - | 7 | 0.001 |
Khalili et al. [25] | 100 | 50% | - | 69 | 100 | 50% | - | 59 | NS |
Gokce et al. [26] | 85 | 47.1% | 42 | 48 | 85 | 43.5% | 42 | 19 | <0.05 |
Molan and Ismail [27] | 69 | 52.2% | 37 | 52 | 203 | 49.3% | 47 | 68 | 0.009 |
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Catchpole, A.; Zabriskie, B.N.; Bassett, P.; Embley, B.; White, D.; Gale, S.D.; Hedges, D. Association between Toxoplasma gondii Infection and Type-1 Diabetes Mellitus: A Systematic Review and Meta-Analysis. Int. J. Environ. Res. Public Health 2023, 20, 4436. https://doi.org/10.3390/ijerph20054436
Catchpole A, Zabriskie BN, Bassett P, Embley B, White D, Gale SD, Hedges D. Association between Toxoplasma gondii Infection and Type-1 Diabetes Mellitus: A Systematic Review and Meta-Analysis. International Journal of Environmental Research and Public Health. 2023; 20(5):4436. https://doi.org/10.3390/ijerph20054436
Chicago/Turabian StyleCatchpole, Ashley, Brinley N. Zabriskie, Pierce Bassett, Bradley Embley, David White, Shawn D. Gale, and Dawson Hedges. 2023. "Association between Toxoplasma gondii Infection and Type-1 Diabetes Mellitus: A Systematic Review and Meta-Analysis" International Journal of Environmental Research and Public Health 20, no. 5: 4436. https://doi.org/10.3390/ijerph20054436