Open Access, Peer-reviewed
pISSN 2287-2434
eISSN 2287-447X
    Asian Oncol Nurs. 2015 Dec;15(4):203-210. Korean.
    Published online Dec 31, 2015.
    https://doi.org/10.5388/aon.2015.15.4.203
    © 2015 Korean Oncology Nursing Society
    Original Article

    Influence of Sleep Disturbance and Depression on Quality of Life in Ovarian Cancer Patients during Chemotherapy

    Sun-Young Yu,1 and Ju-Hee Nho2
      • 1Department of Nursing, Asan Medical Center, Seoul, Korea.
      • 2College of Nursing, Chonnam National University, Gwangju, Korea.
    • Address reprint requests to: Nho, Ju-Hee. College of Nursing, Chonnam National University, 160 Baekseo-ro, Dong-gu, Gwangju 61469, Korea. Tel: +82-62-530-4949, Fax: +82-62-227-4009, Email: jhnho@jnu.ac.kr
    Received August 30, 2015; Revised October 08, 2015; Accepted November 10, 2015.

    This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

    Abstract

    Purpose

    The purpose of this study was to examine the relationships among sleep disturbance, depression, and quality of life in ovarian cancer during chemotherapy and to identify the influencing effect on quality of life.

    Methods

    A cross-sectional survey was conducted to measure sleep disturbance, depression and quality of life of 152 ovarian cancer patients between May and July, 2015. The data were analyzed with t-tests, ANOVA, post-hoc comparison (Scheffé), Pearson's correlation coefficients, and multiple regression analysis.

    Results

    The mean age of the participants was 54.2, and most of them were married. 61.8% of the patients were recurrent, and 50.0% had a performance status of ≤1. The prevalence of poor sleepers was 63.8%, and depression among patients was 52.6%. Sleep disturbance and depression were significantly negatively correlated with quality of life. As a result of stepwise multiple regression analysis, depression, sleep disturbance, monthly income and recurrence were discovered to account for 52.0% of variance. Depression and sleep disturbance were the most important influential factors.

    Conclusion

    The results of the study indicate that sleep disturbance and depression should be integrated when developing and implementing psychosocial, behavioral intervention to improve quality of life among ovarian cancer patients during chemotherapy.

    Keywords
    Sleep; Depression; Quality of Life; Ovarian Neoplasm

    Tables

    Table 1
    Demographic, Clinical, Psychological Characteristics in Patients with Ovarian Cancer (N =152)

    Table 2
    Descriptive Statistics for Sleep Disturbance, Depression and Quality of Life (N =152)

    Table 3
    Comparison of Sleep Disturbance, Depression, and Quality of Life according to Patients Characteristics (N =152)

    Table 4
    Correlation between Sleep Disturbance, Depression and Quality of Life (N =152)

    Table 5
    Influencing Factors on Quality of Life

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    MeSH Terms
    Cross-Sectional Studies
    Depression*
    Drug Therapy*
    Humans
    Ovarian Neoplasms*
    Prevalence
    Quality of Life*
    Recurrence
    Metrics
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