Associations between Metabolic Syndrome and Its Components and Alcohol Drinking

 

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Abstract

Aims: The relationship between alcohol drinking and metabolic syndrome (MetS) and its components are not fully confirmed, we examined relationship between alcohol drinking and MetS and its components.

Methods: 2 538 Mongolian people aged 20 or more were included in this study. The data for demographic characteristics, lifestyle factors, family history of hypertension, blood pressure (BP) measurements and physical examination were obtained, and fasting plasma glucose (FPG) and lipids examined for all participants. Associations between MetS and its components and alcohol drinking were analyzed with Logistic regression.

Results: The risks of MetS associated with alcohol drinking and various drinking volume were not significant after adjustment for other variables. Alcohol drinking was significantly and positively associated with high BP and high TG, the multivariate adjusted OR (95% CI) of high BP and high TG for drinking were 1.399(1.109, 1.764) and 2.464(1.866, 3.252), respectively, compared with no drinking. However, drinking was inversely associated with low HDL-C, the multivariate adjusted OR (95% CI) of low HDL-C was 0.597(0.479, 0.745) for alcohol drinking compared with no drinking.

Conclusions: Alcohol drinking was significantly and positively associated with high BP and high TG, while alcohol drinking inversely associated with low HDL-C.

References

• 1 Arif AA, Rohrer JE. Patterns of alcohol drinking and its association with obesity: data from the Third National Health and Nutrition Examination Survey, 1988–1994.  BMC Public Health. 2005;  5 126
  Google Scholar
• 2 Athyros VG, Liberopoulos EN, Mikhailidis DP. et al . Association of drinking pattern and alcohol beverage type with the prevalence of metabolic syndrome, diabetes, coronary heart disease, stroke, and peripheral arterial disease in a Mediterranean cohort.  Angiology. 2007;  58 689-697
  Google Scholar
• 3 Baik I, Shin C. Prospective study of alcohol consumption and metabolic syndrome.  Am J Clin Nutr. 2008;  87 1455-1463
  Google Scholar
• 4 Chew LD, Nelson KM, Young BA. et al . Association between alcohol consumption and diabetes preventive practices.  Fam Med. 2005;  37 589-594
  Google Scholar
• 5 Fan AZ, Russell M, Dorn J. et al . Lifetime alcohol drinking pattern is related to the prevalence of metabolic syndrome. The Western New York Health Study (WNYHS).  Eur J Epidemiol. 2006;  21 129-138
  Google Scholar
• 6 Fan JG, Cai XB, Li L. et al . Alcohol consumption and metabolic syndrome among Shanghai adults: a randomized multistage stratified cluster sampling investigation.  World J Gastroenterol. 2008;  14 2418-2424
  Google Scholar
• 7 Gordon T, Kannel WB. Drinking habits and cardiovascular disease: the Framingham Study.  Am Heart J. 1983;  105 667-673
  Google Scholar
• 8 Kato I, Kiyohara Y, Kubo M. et al . Insulin-mediated effects of alcohol intake on serum lipid levels in a general population: the Hisayama Study.  J Clin Epidemiol. 2003;  56 196-204
  Google Scholar
• 9 Klatsky AL, Koplik S, Gunderson E. et al . Sequelae of systemic hypertension in alcohol abstainers, light drinkers, and heavy drinkers.  Am J Cardiol. 2006;  98 1063-1068
  Google Scholar
• 10 Lip GY, Beevers DG. Alcohol and cardiovascular disease – more than one paradox to consider. Alcohol and hypertension – does it matter? (no!).  J Cardiovasc Risk. 2003;  10 11-14
  Google Scholar
• 11 Miyao M, Furuta M, Kondo T. et al . The relationship of high-density lipoprotein cholesterol to obesity, drinking and smoking habits.  Nagoya J Med Sci. 1993;  55 65-70
  Google Scholar
• 12 Moore RD, Levine DM, Southard J. et al . Alcohol consumption and blood pressure in the 1982 Maryland Hypertension Survey.  Am J Hypertens. 1990;  3 1-7
  Google Scholar
• 13 Pacholczyk M, Ferenc T, Kowalski J. The metabolic syndrome. Part I: definitions and diagnostic criteria for its identification. Epidemiology and relationship with cardiovascular and type 2 diabetes risk.  Postepy Hig Med Dosw (Online). 2008;  62 530-542
  Google Scholar
• 14 Perry IJ, Wannamethee SG, Walker MK. et al . Prospective study of risk factors for development of non-insulin dependent diabetes in middle aged British men.  BMJ. 1995;  310 560-564
  Google Scholar
• 15 Reaven GM. Role of insulin resistance in human disease (syndrome X): an expanded definition.  Annu Rev Med. 1993;  44 121-131
  Google Scholar
• 16 Rimm EB, Chan J, Stampfer MJ. et al . Prospective study of cigarette smoking, alcohol use, and the risk of diabetes in men.  BMJ. 1995;  310 555-559
  Google Scholar
• 17 Saito Y. Secondary hyperlipidemia due to obesity and alcohol drinking.  Nippon Naika Gakkai Zasshi. 1992;  81 1784-1787
  Google Scholar
• 18 Seike N, Noda M, Kadowaki T. Alcohol consumption and risk of type 2 diabetes mellitus in Japanese: a systematic review.  Asia Pac J Clin Nutr. 2008;  17 545-551
  Google Scholar
• 19 Stranges S, Wu T, Dorn JM. et al . Relationship of alcohol drinking pattern to risk of hypertension: a population-based study.  Hypertension. 2004;  44 813-819
  Google Scholar
• 20 Wang JY, Zhang LJ, Shui LM. et al . Study on the relationship between smoking, alcohol intake and hyperlipidemia in fishermen.  Zhonghua Liu Xing Bing Xue Za Zhi. 2003;  24 1115-1117
  Google Scholar
• 21 Zhang S, Tong W, Wang G. et al . Impaired fasting glucose and cardiovascular risk factor clustering among Mongolian population in rural and animal husbandry area, Inner Mongolia, China.  Diabetes Res Clin Pract. 2010;  89 282-287
  Google Scholar

Correspondence

Y. ZhangMD, PhD 

Department of Epidemiology

School of Radiation Medicine

and Public Health

Medical College of Soochow

University

199 Renai Road

Industrial Park District

215123 Suzhou

China

Phone: +86/512/6588 0078

Fax: +86/512/6588 0052

Email: yhzhang@suda.edu.cn

J. ZhaoPhD 

Department of Epidemiology

School of Public Health

Harbin Medical University

150086 Harbin

China

Phone:

Fax:

Email: