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Endoscopy 2008; 40(4): 343-346
DOI: 10.1055/s-2007-995365
Case report

© Georg Thieme Verlag KG Stuttgart · New York

Primary follicular lymphoma of the gastrointestinal tract: a retrospective case series

M.  Kodama1 , Y.  Kitadai1 , T.  Shishido1 , M.  Shimamoto1 , A.  Fukumoto1 , H.  Masuda1 , S.  Tanaka2 , M.  Yoshihara3 , A.  Sakai4 , H.  Nakayama5 , K.  Chayama1
  • 1Department of Medicine and Molecular Science, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan
  • 2Department of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan
  • 3Health Service Center, Hiroshima University, Higashi-Hiroshima, Japan
  • 4Department of Hematology and Oncology, RIRBM Hiroshima University, Hiroshima, Japan
  • 5Department of Molecular Pathology, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan
Further Information

Publication History

submitted 14 August 2007

accepted after revision 7 November 2007

Publication Date:
07 December 2007 (online)

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Little is known about the clinicopathologic characteristics of primary follicular lymphoma of the gastrointestinal tract (PFLGI). We report our experience with double-balloon enteroscopy (DBE) in patients with PFLGI. Between January 2001 and December 2006, thirteen patients with PFLGI (nine men and four women; mean age, 53.4 years) visited Hiroshima University Hospital. We performed DBE in 11 PFLGI patients to examine the entire small bowel. DBE showed new lesions in the third portion of the duodenum, jejunum, or ileum in nine of these 11 patients (81.8 %). The endoscopic finding was nodularity of the involved mucosal surface (small whitish polyps or whitish granules). Seven patients were treated with rituximab plus CHOP chemotherapy (R-CHOP). A complete response was obtained in all patients who received R-CHOP, and no recurrence was seen (mean follow-up period, 22.5 months).

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Y. Kitadai, MD

Hiroshima University Graduate School of Biomedical Sciences

1-2-3 Kasumi

Minami-ku

Hiroshima 734-8551

Japan

Fax: + 81-82-2575194

Email: kitadai@hiroshima-u.ac.jp

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