Abstract
There are many important considerations in the design, construction, and use of a bioreactor for growing hollow organs such as vessels, gastrointestinal tissue, esophagus, and others. The growth of new organs requires a specialized container that provides sterility and an environment conducive to cell-seeding and attachment onto a three-dimensional bioabsorbable porous scaffold, incubation, maturation, and shipping for implantation. The materials’ selection, dimensions, manufacturing, testing, and use of the bioreactor are all factors that should be considered in designing a bioreactor for the development of hollow organs.
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© 2013 Springer Science+Business Media New York
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Fish, J., Halberstadt, C., McCoy, D.W., Robbins, N. (2013). Bioreactor Design Considerations for Hollow Organs. In: Basu, J., Ludlow, J. (eds) Organ Regeneration. Methods in Molecular Biology, vol 1001. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-363-3_18
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DOI: https://doi.org/10.1007/978-1-62703-363-3_18
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Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-62703-362-6
Online ISBN: 978-1-62703-363-3
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