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European Journal of Nutrition

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03.12.2021 | Original Contribution

Associations of dietary, lifestyle, other participant characteristics, and oxidative balance scores with plasma F₂-isoprostanes concentrations in a pooled cross-sectional study

verfasst von: Ziling Mao, Roberd M. Bostick

Erschienen in: European Journal of Nutrition | Ausgabe 3/2022

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Abstract

Purpose

Plasma F₂-isoprostanes (FiP) concentration, a reliably measured, valid, systemic oxidative stress biomarker, has been associated with multiple health-related outcomes; however, associations of most individual dietary and lifestyle exposures with FiP are unclear, and there is no reported oxidative balance score (OBS) comprising multiple dietary and/or lifestyle components weighted by their associations with FiP.

Methods

To investigate cross-sectional associations of dietary and lifestyle characteristics with plasma FiP concentrations, we used multivariable general linear models to compare adjusted mean FiP concentrations across categories of dietary nutrient and whole-food intakes and lifestyle characteristics in two pooled cross-sectional studies (n = 386). We also developed equal-weight and weighted OBS (nutrient- and foods-based dietary OBS, lifestyle OBS, and total OBS), and compared adjusted mean FiP concentrations across OBS tertiles.

Results

Among men and women combined, adjusted mean FiP concentrations were statistically significantly, proportionately 28.1% higher among those who were obese relative to those who were normal weight; among those in the highest relative to the lowest total nutrient intake tertiles, FiP concentrations were statistically significantly lower by 9.8% for carotenes, 13.6% for lutein/zeaxanthin, 10.9% for vitamin C, 12.2% for vitamin E, 11.5% for glucosinolates, and 5% for calcium. Of the various OBS, the weighted OBS that combined total nutrient intakes and lifestyle exposures was most strongly associated with FiP concentrations: among those in the highest relative to the lowest total OBS, mean FiP concentrations were statistically significantly 29.7% lower (P < 0.001).

Conclusion

Multiple dietary and lifestyle characteristics, individually, and especially collectively, may contribute to systemic oxidative stress.

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Sies H (1997) Oxidative stress: oxidants and antioxidants. Exp Physiol Transl Integr 82:291–295CrossRef

Storz G, Imlayt JA (1999) Oxidative stress. Curr Opin Microbiol 2:188–194CrossRefPubMed

Sies H (2000) What is oxidative stress? Oxidative stress and vascular disease. Springer, New York, pp 1–8

Schottker B, Brenner H, Jansen EH et al (2015) Evidence for the free radical/oxidative stress theory of ageing from the CHANCES consortium: a meta-analysis of individual participant data. BMC Med 13:300. https://doi.org/10.1186/s12916-015-0537-7CrossRefPubMedPubMedCentral

Salminen A, Ojala J, Kaarniranta K et al (2012) Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases. Cell Mol Life Sci 69:2999–3013. https://doi.org/10.1007/s00018-012-0962-0CrossRefPubMed

Schottker B, Saum KU, Jansen EH et al (2015) Oxidative stress markers and all-cause mortality at older age: a population-based cohort study. J Gerontol A Biol Sci Med Sci 70:518–524. https://doi.org/10.1093/gerona/glu111CrossRefPubMed

Montuschi P, Barnes PJ, Roberts LJ 2nd (2004) Isoprostanes: markers and mediators of oxidative stress. Faseb j 18:1791–1800. https://doi.org/10.1096/fj.04-2330revCrossRefPubMed

Milne GL, Musiek ES, Morrow JD (2005) F2-isoprostanes as markers of oxidative stress in vivo: an overview. Biomarkers 10(Suppl 1):S10-23. https://doi.org/10.1080/13547500500216546CrossRefPubMed

Liu T, Stern A, Roberts LJ et al (1999) The isoprostanes: novel prostaglandin-like products of the free radical-catalyzed peroxidation of arachidonic acid. J Biomed Sci 6:226–235. https://doi.org/10.1007/bf02253564CrossRefPubMed

10.

Morrow JD, Roberts LJ (1997) The isoprostanes: unique bioactive products of lipid peroxidation. Prog Lipid Res 36:1–21. https://doi.org/10.1016/s0163-7827(97)00001-5CrossRefPubMed

11.

Roberts LJ, Morrow JD (2000) Measurement of F(2)-isoprostanes as an index of oxidative stress in vivo. Free Radic Biol Med 28:505–513. https://doi.org/10.1016/s0891-5849(99)00264-6CrossRefPubMed

12.

Morrow JD, Roberts LJ 2nd (1999) Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress. Methods Enzymol 300:3–12. https://doi.org/10.1016/s0076-6879(99)00106-8CrossRefPubMed

13.

Morrow JD, Zackert WE, Yang JP et al (1999) Quantification of the major urinary metabolite of 15–F2t-isoprostane (8-iso-PGF2alpha) by a stable isotope dilution mass spectrometric assay. Anal Biochem 269:326–331. https://doi.org/10.1006/abio.1999.4008CrossRefPubMed

14.

Morrow JD (2000) The isoprostanes: their quantification as an index of oxidant stress status in vivo. Drug Metab Rev 32:377–385. https://doi.org/10.1081/dmr-100102340CrossRefPubMed

15.

Block G, Dietrich M, Norkus EP et al (2002) Factors associated with oxidative stress in human populations. Am J Epidemiol 156:274–285. https://doi.org/10.1093/aje/kwf029CrossRefPubMed

16.

Keaney JF Jr, Larson MG, Vasan RS et al (2003) Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study. Arterioscler Thromb Vasc Biol 23:434–439. https://doi.org/10.1161/01.Atv.0000058402.34138.11CrossRefPubMed

17.

Helmersson J, Larsson A, Vessby B et al (2005) Active smoking and a history of smoking are associated with enhanced prostaglandin F(2alpha), interleukin-6 and F2-isoprostane formation in elderly men. Atherosclerosis 181:201–207. https://doi.org/10.1016/j.atherosclerosis.2004.11.026CrossRefPubMed

18.

Tomey KM, Sowers MR, Li X et al (2007) Dietary fat subgroups, zinc, and vegetable components are related to urine F2a-isoprostane concentration, a measure of oxidative stress, in midlife women. J Nutr 137:2412–2419. https://doi.org/10.1093/jn/137.11.2412CrossRefPubMed

19.

Basu S, Helmersson J, Jarosinska D et al (2009) Regulatory factors of basal F(2)-isoprostane formation: population, age, gender and smoking habits in humans. Free Radic Res 43:85–91. https://doi.org/10.1080/10715760802610851CrossRefPubMed

20.

Sakano N, Takahashi N, Wang DH et al (2009) Plasma 3-nitrotyrosine, urinary 8-isoprostane and 8-OHdG among healthy Japanese people. Free Radic Res 43:183–192. https://doi.org/10.1080/10715760802663124CrossRefPubMed

21.

Sakano N, Wang DH, Takahashi N et al (2009) Oxidative stress biomarkers and lifestyles in Japanese healthy people. J Clin Biochem Nutr 44:185–195. https://doi.org/10.3164/jcbn.08-252CrossRefPubMedPubMedCentral

22.

Vetrani C, Costabile G, Di Marino L et al (2013) Nutrition and oxidative stress: a systematic review of human studies. Int J Food Sci Nutr 64:312–326. https://doi.org/10.3109/09637486.2012.738651CrossRefPubMed

23.

Boyapati SM, Bostick RM, McGlynn KA et al (2003) Calcium, vitamin D, and risk for colorectal adenoma: dependency on vitamin D receptor BsmI polymorphism and nonsteroidal anti-inflammatory drug use? Cancer Epidemiol Biomarkers Prev 12:631–637PubMed

24.

Daniel CR, Bostick RM, Flanders WD et al (2009) TGF-alpha expression as a potential biomarker of risk within the normal-appearing colorectal mucosa of patients with and without incident sporadic adenoma. Cancer Epidemiol Biomarkers Prev 18:65–73. https://doi.org/10.1158/1055-9965.Epi-08-0732CrossRefPubMedPubMedCentral

25.

MacIntosh DL, Williams PL, Hunter DJ et al (1997) Evaluation of a food frequency questionnaire-food composition approach for estimating dietary intake of inorganic arsenic and methylmercury. Cancer Epidemiol Biomarkers Prev 6:1043–1050PubMed

26.

Willett WC, Sampson L, Stampfer MJ et al (1985) Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol 122:51–65. https://doi.org/10.1093/oxfordjournals.aje.a114086CrossRefPubMed

27.

Paffenbarger RS Jr, Blair SN, Lee IM et al (1993) Measurement of physical activity to assess health effects in free-living populations. Med Sci Sports Exerc 25:60–70. https://doi.org/10.1249/00005768-199301000-00010CrossRefPubMed

28.

Dash C, Bostick RM, Goodman M et al (2015) Oxidative balance scores and risk of incident colorectal cancer in a US prospective cohort study. Am J Epidemiol 181:584–594. https://doi.org/10.1093/aje/kwu318CrossRefPubMed

29.

Dash C, Goodman M, Flanders WD et al (2013) Using pathway-specific comprehensive exposure scores in epidemiology: application to oxidative balance in a pooled case-control study of incident, sporadic colorectal adenomas. Am J Epidemiol 178:610–624. https://doi.org/10.1093/aje/kwt007CrossRefPubMedPubMedCentral

30.

Morrow JD, Roberts LJ 2nd (1994) Mass spectrometry of prostanoids: F2-isoprostanes produced by non-cyclooxygenase free radical-catalyzed mechanism. Methods Enzymol 233:163–174. https://doi.org/10.1016/s0076-6879(94)33019-0CrossRefPubMed

31.

Bieri JG, Brown ED, Smith JC Jr (1985) Determination of individual carotenoids in human plasma by high performance liquid chromatography. J Liq Chromatogr 8:473–484CrossRef

32.

Craft NE, Brown ED, Smith JC Jr (1988) Effects of storage and handling conditions on concentrations of individual carotenoids, retinol, and tocopherol in plasma. Clin Chem 34:44–48CrossRefPubMed

33.

Gross MD, Prouty CB, Jacobs DR Jr (1995) Stability of carotenoids and alpha-tocopherol during blood collection and processing procedures. Clin Chem 41:943–944CrossRefPubMed

34.

Lee D-H, Gross MD, Jacobs DR Jr (2004) Association of serum carotenoids and tocopherols with γ-glutamyltransferase: the Cardiovascular Risk Development in Young Adults (CARDIA) study. Clin Chem 50:582–588CrossRefPubMed

35.

Byrd DA, Judd SE, Flanders WD et al (2019) Development and Validation of Novel Dietary and Lifestyle Inflammation Scores. J Nutr 149:2206–2218. https://doi.org/10.1093/jn/nxz165CrossRefPubMedPubMedCentral

36.

Mao Z, Prizment AE, Lazovich D et al (2020) Dietary and Lifestyle Oxidative Balance Scores and Incident Colorectal Cancer Risk among Older Women; the Iowa Women’s Health Study. Nutr Cancer. https://doi.org/10.1080/01635581.2020.1821904CrossRefPubMed

37.

Reuter S, Gupta SC, Chaturvedi MM et al (2010) Oxidative stress, inflammation, and cancer: how are they linked? Free Radic Biol Med 49:1603–1616. https://doi.org/10.1016/j.freeradbiomed.2010.09.006CrossRefPubMedPubMedCentral

38.

Burton G, Ingold K (1989) Vitamin E as an in vitro and in vivo antioxidant. Ann N Y Acad Sci 570:7–22CrossRefPubMed

39.

Kojo S (2004) Vitamin C: basic metabolism and its function as an index of oxidative stress. Curr Med Chem 11:1041–1064. https://doi.org/10.2174/0929867043455567CrossRefPubMed

40.

Juge N, Mithen RF, Traka M (2007) Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cell Mol Life Sci 64:1105–1127. https://doi.org/10.1007/s00018-007-6484-5CrossRefPubMed

41.

Rao AV, Rao LG (2007) Carotenoids and human health. Pharmacol Res 55:207–216. https://doi.org/10.1016/j.phrs.2007.01.012CrossRefPubMed

42.

Anderson C, Milne GL, Sandler DP et al (2016) Oxidative stress in relation to diet and physical activity among premenopausal women. Br J Nutr 116:1416–1424. https://doi.org/10.1017/s0007114516003226CrossRefPubMedPubMedCentral

43.

Thomson CA, Stendell-Hollis NR, Rock CL et al (2007) Plasma and dietary carotenoids are associated with reduced oxidative stress in women previously treated for breast cancer. Cancer Epidemiol Biomarkers Prev 16:2008–2015. https://doi.org/10.1158/1055-9965.Epi-07-0350CrossRefPubMedPubMedCentral

44.

Cocate PG, Natali AJ, Alfenas RC et al (2015) Carotenoid consumption is related to lower lipid oxidation and DNA damage in middle-aged men. Br J Nutr 114:257–264. https://doi.org/10.1017/s0007114515001622CrossRefPubMed

45.

Helmersson J, Arnlöv J, Larsson A et al (2009) Low dietary intake of beta-carotene, alpha-tocopherol and ascorbic acid is associated with increased inflammatory and oxidative stress status in a Swedish cohort. Br J Nutr 101:1775–1782. https://doi.org/10.1017/s0007114508147377CrossRefPubMed

46.

Thompson HJ, Heimendinger J, Gillette C et al (2005) In vivo investigation of changes in biomarkers of oxidative stress induced by plant food rich diets. J Agric Food Chem 53:6126–6132. https://doi.org/10.1021/jf050493xCrossRefPubMed

47.

Thompson HJ, Heimendinger J, Sedlacek S et al (2005) 8-Isoprostane F2alpha excretion is reduced in women by increased vegetable and fruit intake. Am J Clin Nutr 82:768–776. https://doi.org/10.1093/ajcn/82.4.768CrossRefPubMed

48.

Cocate PG, Natali AJ, Oliveira A et al (2014) Fruit and vegetable intake and related nutrients are associated with oxidative stress markers in middle-aged men. Nutrition 30:660–665. https://doi.org/10.1016/j.nut.2013.10.015CrossRefPubMed

49.

Thompson HJ, Heimendinger J, Haegele A et al (1999) Effect of increased vegetable and fruit consumption on markers of oxidative cellular damage. Carcinogenesis 20:2261–2266. https://doi.org/10.1093/carcin/20.12.2261CrossRefPubMed

50.

Furukawa S, Fujita T, Shimabukuro M et al (2004) Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Investig 114:1752–1761. https://doi.org/10.1172/jci21625CrossRefPubMedPubMedCentral

51.

Wagner G, Lindroos-Christensen J, Einwallner E et al (2017) HO-1 inhibits preadipocyte proliferation and differentiation at the onset of obesity via ROS dependent activation of Akt2. Sci Rep 7:40881. https://doi.org/10.1038/srep40881CrossRefPubMedPubMedCentral

52.

Fernandez-Sanchez A, Madrigal-Santillan E, Bautista M et al (2011) Inflammation, oxidative stress, and obesity. Int J Mol Sci 12:3117–3132. https://doi.org/10.3390/ijms12053117CrossRefPubMedPubMedCentral

53.

Manna P, Jain SK (2015) Obesity, Oxidative Stress, Adipose Tissue Dysfunction, and the Associated Health Risks: Causes and Therapeutic Strategies. Metab Syndr Relat Disord 13:423–444. https://doi.org/10.1089/met.2015.0095CrossRefPubMedPubMedCentral

54.

Alkazemi D, Egeland GM, Roberts LJ 2nd et al (2012) Isoprostanes and isofurans as non-traditional risk factors for cardiovascular disease among Canadian Inuit. Free Radic Res 46:1258–1266. https://doi.org/10.3109/10715762.2012.702900CrossRefPubMed

55.

Loft S, Vistisen K, Ewertz M et al (1992) Oxidative DNA damage estimated by 8-hydroxydeoxyguanosine excretion in humans: influence of smoking, gender and body mass index. Carcinogenesis 13:2241–2247. https://doi.org/10.1093/carcin/13.12.2241CrossRefPubMed

56.

Irie M, Tamae K, Iwamoto-Tanaka N et al (2005) Occupational and lifestyle factors and urinary 8-hydroxydeoxyguanosine. Cancer Sci 96:600–606. https://doi.org/10.1111/j.1349-7006.2005.00083.xCrossRefPubMed

57.

Tamae K, Kawai K, Yamasaki S et al (2009) Effect of age, smoking and other lifestyle factors on urinary 7-methylguanine and 8-hydroxydeoxyguanosine. Cancer Sci 100:715–721. https://doi.org/10.1111/j.1349-7006.2009.01088.xCrossRefPubMed

58.

Dorjgochoo T, Gao YT, Chow WH et al (2011) Obesity, age, and oxidative stress in middle-aged and older women. Antioxid Redox Signal 14:2453–2460. https://doi.org/10.1089/ars.2010.3337CrossRefPubMedPubMedCentral

59.

Black CN, Bot M, Scheffer PG et al (2016) Sociodemographic and Lifestyle Determinants of Plasma Oxidative Stress Markers 8-OHdG and F2-Isoprostanes and Associations with Metabolic Syndrome. Oxid Med Cell Longev 2016:7530820. https://doi.org/10.1155/2016/7530820CrossRefPubMedPubMedCentral

60.

Harman SM, Liang L, Tsitouras PD et al (2003) Urinary excretion of three nucleic acid oxidation adducts and isoprostane F(2)alpha measured by liquid chromatography-mass spectrometry in smokers, ex-smokers, and nonsmokers. Free Radic Biol Med 35:1301–1309. https://doi.org/10.1016/j.freeradbiomed.2003.07.003CrossRefPubMed

61.

Duggan C, Tapsoba JD, Wang CY et al (2016) Dietary weight loss, exercise, and oxidative stress in postmenopausal women: a randomized controlled trial. Cancer Prev Res (Phila) 9:835–843. https://doi.org/10.1158/1940-6207.CAPR-16-0163CrossRef

62.

Ide T, Tsutsui H, Ohashi N et al (2002) Greater oxidative stress in healthy young men compared with premenopausal women. Arterioscler Thromb Vasc Biol 22:438–442. https://doi.org/10.1161/hq0302.104515CrossRefPubMed

63.

Schisterman EF, Gaskins AJ, Mumford SL et al (2010) Influence of endogenous reproductive hormones on F2-isoprostane levels in premenopausal women: the BioCycle Study. Am J Epidemiol 172:430–439. https://doi.org/10.1093/aje/kwq131CrossRefPubMedPubMedCentral

64.

Sowers M, McConnell D, Jannausch ML et al (2008) Oestrogen metabolites in relation to isoprostanes as a measure of oxidative stress. Clin Endocrinol (Oxf) 68:806–813. https://doi.org/10.1111/j.1365-2265.2007.03108.xCrossRef

65.

Hernandez-Ruiz A, Garcia-Villanova B, Guerra-Hernandez E et al (2019) A review of a priori defined oxidative balance scores relative to their components and impact on health outcomes. Nutrients. https://doi.org/10.3390/nu11040774CrossRefPubMedPubMedCentral

Titel: Associations of dietary, lifestyle, other participant characteristics, and oxidative balance scores with plasma F2-isoprostanes concentrations in a pooled cross-sectional study
verfasst von: Ziling Mao
Roberd M. Bostick
Publikationsdatum: 03.12.2021
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Nutrition / Ausgabe 3/2022
Print ISSN: 1436-6207
Elektronische ISSN: 1436-6215
DOI: https://doi.org/10.1007/s00394-021-02754-2

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Associations of dietary, lifestyle, other participant characteristics, and oxidative balance scores with plasma F₂-isoprostanes concentrations in a pooled cross-sectional study

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