Skip to main content

Clinical and Experimental Medicine

Ausgabe 7/2023

Inhalt (91 Artikel)

Review

Viruses and celiac disease: what do we know ?

Ramon Cohen, Keren Mahlab-Guri, Malka Atali, Daniel Elbirt

Review

Molecular mechanisms of action of metformin: latest advances and therapeutic implications

Hong Zhu, Zhenquan Jia, Yunbo Robert Li, Igor Danelisen

Review

Ubiquitin-specific peptidase 1: assessing its role in cancer therapy

Peng Huang, YuHan Wang, PengFei Zhang, Qiu Li

Review

Interesting effects of interleukins and immune cells on acute respiratory distress syndrome

Najmaldin Saki, Mohammadreza Javan, Bahareh Moghimian-Boroujeni, Richard Eric Kast

Review

Progress in research on mesenchymal stem cells and their extracellular vesicles for treating fibrosis in systemic sclerosis

Yu Xiao, Zhongzhou Huang, Yingyu Wang, Ji Yang, Weiguo Wan, Hejian Zou, Xue Yang

Review

Efficacy and safety of novel biologics in the treatment of lupus nephritis based on registered clinical trials: a systematic review and network meta-analysis

Feigao Li, Wenyan Cui, Guangliang Huang, Yunfei Tian, Xinhui Zhang, Wenjuan He, Qian Sun, Xiaojuan Zhao, Yonghong Zhao, Dan Li, Xizhe Liu, Xiuju Liu

Review

Frontiers of ankylosing spondylitis research: an analysis from the top 100 most influential articles in the field

Xuhao Li, Wenyan Yu, Zhixia Jia, Jinling Li, Yuanxiang Liu, Jiguo Yang

Review

Denosumab for giant cell tumors of bone from 2010 to 2022: a bibliometric analysis

Xiaoqi Tan, Yue Zhang, Daiqing Wei, Yunkang Yang, Feifan Xiang

Review

SRPKs: a promising therapeutic target in cancer

Muhammad Tufail, Changxin Wu

Review

The roles of FHL2 in cancer

Jiawei Zhang, Qun Zeng, Meihua She

Review

JAK/STAT signaling and cellular iron metabolism in hepatocellular carcinoma: therapeutic implications

Bilal Rah, Nada Mazen Farhat, Mawieh Hamad, Jibran Sualeh Muhammad

Review

The benefits of neoadjuvant therapy for patients with resectable pancreatic cancer: an updated systematic review and meta-analysis

Bohan Yang, Kai Chen, Weikang Liu, Di Long, Yingjin Wang, Xinxin Liu, Yongsu Ma, Xiaodong Tian, Yinmo Yang

Open Access Review

A review on the role of HAND2-AS1 in cancer

Soudeh Ghafouri-Fard, Bashdar Mahmud Hussen, Snur Rasool Abdullah, Maryam Dadyar, Mohammad Taheri, Arda Kiani

Review

Immunology and immunotherapy in gastric cancer

Xiaqing Xu, Jiaxing Chen, Wenxing Li, Chenlu Feng, Qian Liu, Wenfang Gao, Meng He

Review

Efficacy of anti-HER2 drugs in the treatment of patients with HER2-mutated cancers: a systematic review and meta-analysis

Yonghui Zheng, Guoshuang Shen, Chengrong Zhang, Xingfa Huo, Yuanfang Xin, Qianqian Fang, Yumei Guan, Fuxing Zhao, Dengfeng Ren, Zhen Liu, Miaozhou Wang, Jiuda Zhao

Review

The impact of antifungal prophylaxis in patients diagnosed with acute leukemias undergoing induction chemotherapy: a systematic review and meta-analysis

Luiz Ricardo Soldi, Yasmin Nascimento Bernardes Coelho, Luiz Renato Paranhos, Marcelo José Barbosa Silva

Open Access Review

A systematic review of the clinical characteristics of influenza-COVID-19 co-infection

Karan Varshney, Preshon Pillay, Ashmit Daiyan Mustafa, Dennis Shen, Jenna Renee Adalbert, Malik Quasir Mahmood

Review

The kinetics of inhibitory immune checkpoints during and post-COVID-19: the knowns and unknowns

Ensiye Torki, Arezou Gharezade, Mehrnoosh Doroudchi, Shima Sheikhi, Davood Mansury, Mark J. M. Sullman, Hamed Fouladseresht

Open Access Review

Autoimmune liver disease and multiple sclerosis: state of the art and future perspectives

Rosanna Villani, Gaetano Serviddio, Carlo Avolio, Tommaso Cassano, Emanuele D’Amico

Review

Ménière’s disease and allergy: Epidemiology, pathogenesis, and therapy

Wandi Xu, Xiaofei Li, Yongdong Song, Ligang Kong, Na Zhang, Jiahui Liu, Guorong Li, Zhaomin Fan, Yafeng Lyu, Daogong Zhang, Haibo Wang, Na Li

Open Access Review

Lipid metabolic vulnerabilities of multiple myeloma

Roberta Torcasio, Maria Eugenia Gallo Cantafio, Raissa Kaori Ikeda, Ludovica Ganino, Giuseppe Viglietto, Nicola Amodio

Research

Predictors of complete 24-month remission and flare in patients with polymyalgia rheumatica

Carlo Perricone, Giacomo Cafaro, Elena Fiumicelli, Roberto Bursi, Dimitrios Bogdanos, Ilenia Riccucci, Roberto Gerli, Elena Bartoloni

Research

Long-term follow-up of Iranian male patients with systemic lupus erythematosus

Abbas Smiley, Mohammad Matinfar, Alimohammad Fatemi

Research

Differences and similarities in cytokine profiles of macrophage activation syndrome in systemic lupus erythematosus and adult-onset Still’s disease

Tomoka Hiyama, Kazuhiro Kurasawa, Anna Hasegawa, Tomoyuki Miyao, Ayae Tanaka, Satoko Arai, Masafumi Arima, Reika Maezawa

Open Access Research

Metabolic profiling of patients with different idiopathic inflammatory myopathy subtypes reveals potential biomarkers in plasma

Qianqian Zhao, Qiu Hu, Shuhui Meng, Qinguo Zhang, Tingting Wang, Cuilian Liu, Dongzhou Liu, Zhenyou Jiang, Xiaoping Hong

Research

Subclinical atherosclerosis in Behcet’s disease and its inverse relation to azathioprine use: an updated meta-analysis

Mira Merashli, Tommaso Bucci, Alessia Arcaro, Fabrizio Gentile, Paul R. J. Ames

Research

Prokineticin 2 as a potential biomarker for the diagnosis of Kawasaki disease

Li Zeng, Cai Wang, Zhixin Song, Qian Liu, Dapeng Chen, Xiaoyan Yu

Open Access Research

Clinical significance of serum antinuclear antibodies in patients with autoimmune hepatitis and comorbidity

Hui Liu, Yuqi Wang, Peng Wang, Xin Wang, Yunyun Yi, Xin Li

Research

SIRT1 slows the progression of lupus nephritis by regulating the NLRP3 inflammasome through ROS/TRPM2/Ca2+ channel

Jihua Tian, Taiping Huang, Jingshu Chen, Jing Wang, Sijia Chang, Huanyu Xu, Xiaoshuang Zhou, Jia Yang, Yuan Xue, Tingting Zhang, Weiping Fan, Yanhong Wang

Open Access Research

IL-6-induced response of human osteoblasts from patients with rheumatoid arthritis after inhibition of the signaling pathway

Marie-Luise Sellin, Annett Klinder, Philipp Bergschmidt, Rainer Bader, Anika Jonitz-Heincke

Open Access Research

The efficacy of aspirin to inhibit platelet aggregation in patients hospitalised with a severe infection: a multicentre, open-label, randomised controlled trial

Lieve Mees van Zijverden, Moya Henriëtte Schutte, Milou Cecilia Madsen, Tobias Nicolaas Bonten, Yvo Michiel Smulders, Chantal Maria Wiepjes, Jeske Joanna Katarina van Diemen, Abel Thijs

Research

NSAIDs use history: impact on the genome-wide DNA methylation profile and possible mechanisms of action

Pedro S. Marra, Yoshitaka Nishizawa, Takehiko Yamanashi, Eleanor J. Sullivan, Katie R. Comp, Kaitlyn J. Crutchley, Nadia E. Wahba, Kazuki Shibata, Tsuyoshi Nishiguchi, Kyosuke Yamanishi, Nicolas O. Noiseux, Matthew D. Karam, Gen Shinozaki

Open Access Research

Type 2 cytokines and scleroderma interstitial lung disease

Chiara Pellicano, Lorenzo Vantaggio, Amalia Colalillo, Krizia Pocino, Valerio Basile, Mariapaola Marino, Umberto Basile, Edoardo Rosato

Research

Clinical features and relapse risks factors of IgG4 related disease: a single-center retrospective study

Xinhe Zhang, Zilu Zeng, Haoyu Tian, Ningning Wang, Ying Wang, Jing Tong, Bing Chang, Xiuli Jin, Die Huang, Yanmeng Wang, Huipeng Cui, Lin Guan, Yiling Li

Open Access Research

Cytotoxic NK cells phenotype and activated lymphocytes are the main characteristics of patients with alcohol-associated liver disease

Coral Zurera-Egea, Aina Teniente-Serra, Daniel Fuster, Eva Martínez-Cáceres, Roberto Muga, Paola Zuluaga

Open Access Research

Knowledge mapping of COVID-19 and autoimmune diseases: a visual and bibliometric analysis

Youao Zhang, Zixuan Jia, Xu Xia, Jieyan Wang

Research

Sex disparities in clinicopathological features and outcomes of patients with myeloperoxidase-ANCA-associated vasculitis: a retrospective study of 366 cases in a single Chinese center

Ting Meng, Peng Zhu, Chanjuan Shen, Joshua D. Ooi, Peter Eggenhuizen, Ya-Ou Zhou, Hui Luo, Jin-Biao Chen, Wei Lin, Qi Xiong, Yizi Gong, Rong Tang, Xiang Ao, Weisheng Peng, Zhou Xiao, Ping Xiao, Xiangcheng Xiao, Yong Zhong

Research

Pattern and clinical correlates of renal iron deposition in adult beta-thalassemia major patients

Antonella Meloni, Luigi Barbuto, Vincenzo Positano, Laura Pistoia, Anna Spasiano, Tommaso Casini, Francesco Massei, Crocetta Argento, Piera Giovangrossi, Angelica Barone, Luigia Romano, Filippo Cademartiri

Research

Clinical characteristics, diagnosis and management of Sweet syndrome induced by azathioprine

Zhiqiang Fan, Yang He, Wei Sun, Zuojun Li, Chao Ye, Chunjiang Wang

Research

Increased serum soluble interleukin-2 receptor levels in dermatomyositis are associated with Th17/Treg immune imbalance

Yuhuan Xie, Tingting Zhang, Rui Su, Lu Liu, Lei Jiang, Hongwei Xue, Chong Gao, Xiaofeng Li, Caihong Wang

Research

ATPergic signaling disruption in human sepsis as a potential source of biomarkers for clinical use

R. O. Leite, P. O. de Souza, C. B. Haas, F. da Silveira, K. R. Mohr, A. P. S. Bertoni, M. S. Soares, J. H. Azambuja, M. Dal Prá, L. L. P. da Cruz, N. E. Gelsleichter, K. Begnini, G. Hasko, M. R. Wink, R. M. Spanevello, E. Braganhol

Research

Five cluster classifications of long COVID and their background factors: A cross-sectional study in Japan

Tomoya Tsuchida, Naohito Yoshimura, Kosuke Ishizuka, Kohta Katayama, Yoko Inoue, Masanori Hirose, Yu Nakagama, Yasutoshi Kido, Hiroki Sugimori, Takahide Matsuda, Yoshiyuki Ohira

Research

Side effects of COVID-19 vaccinations in patients treated for breast cancer

Brooke C. Juhel, Cheryl L. Brunelle, Madison C. Bernstein, Louisa H. Smith, Amanda W. Jung, Hazim S. Ababneh, Elizabeth K. Hausman, Loryn K. Bucci, Tess Bernstein, George E. Naoum, Alphonse G. Taghian

Open Access Research

Interleukin-62/lymphocyte as a proposed predictive index for COVID-19 patients treated with monoclonal antibodies

Salvatore Rotundo, Massimo Borelli, Vincenzo Scaglione, Rosaria Lionello, Flavia Biamonte, Vincenzo Olivadese, Angela Quirino, Helen Linda Morrone, Giovanni Matera, Francesco Saverio Costanzo, Alessandro Russo, Enrico Maria Trecarichi, Carlo Torti, Francesca Serapide, Bruno Tassone, Paolo Fusco, Chiara Davoli, Valentina La Gamba, Helen Linda Morrone, Lavinia Berardelli, Maria Teresa Tassone, Riccardo Serraino, Chiara Costa, Daniela Patrizia Foti, Federico Longhini, Andrea Bruni, Eugenio Garofalo, Eugenio Biamonte, Domenico Laganà, Maria Petullà, Bernardo Bertucci, Giorgio Settimo Barreca, Aida Giancotti, Luigia Gallo, Angelo Lamberti, Maria Carla Liberto, Nadia Marascio, Adele Emanuela De Francesco

Open Access Research

90K/LGALS3BP expression is upregulated in COVID-19 but may not restrict SARS-CoV-2 infection

Laure Bosquillon de Jarcy, Bengisu Akbil, Baxolele Mhlekude, Johanna Leyens, Dylan Postmus, Greta Harnisch, Jenny Jansen, Marie L. Schmidt, Annette Aigner, Fabian Pott, Robert Lorenz Chua, Lilian Krist, Roberta Gentile, Barbara Mühlemann, Terence C. Jones, Daniela Niemeyer, Julia Fricke, Thomas Keil, Tobias Pischon, Jürgen Janke, Christian Conrad, Stefano Iacobelli, Christian Drosten, Victor M. Corman, Markus Ralser, Roland Eils, Florian Kurth, Leif Sander, Christine Goffinet

Research

Remdesivir in pregnant women with moderate to severe coronavirus disease 2019 (COVID-19): a retrospective cohort study

Taraneh Arbabzadeh, Maryam Masoumi Shahrbabak, Parichehr Pooransari, Mahdi Khatuni, Masoumeh Mirzamoradi, Soraya Saleh Gargari, Zahra Naeiji, Nayereh Rahmati, Samaneh Omidi, Faridadin Ebrahimi Meimand

Research

Interactions and clinical implications of serological and respiratory variables 3 months after acute COVID-19

Ophir Freund, Anna Breslavsky, Sabrina Fried, Rotem Givoli-Vilensky, Shira Cohen-Rubin, Nadav Zacks, Eyal Kleinhendler, Avraham Unterman, Shir Frydman, Ori Wand, Natalya Bilenko, Amir Bar-Shai

Research

MicroRNA expression in osteoarthritis: a meta-analysis

Huachen Liu, Lei Yan, Xiaoke Li, Dijun Li, Guishan Wang, Nan-Nan Shen, Jiao Jiao Li, Bin Wang

Research

Beta2-microglobulin is a valuable marker and identifies a poor-prognosis subgroup among intermediate-risk patients with diffuse large B cell lymphoma

Ning-Chun Chen, Hung Chang, Hsiao-Wen Kao, Che-Wei Ou, Ming-Chung Kuo, Po-Nan Wang, Tung-Liang Lin, Jin-Hou Wu, Yu-Shin Hung, Yi-Jiun Su, Yuen-Chin Ong, Hsuan-Jen Shih

Research

An HPK1 inhibitor enhanced the tumour response to anti-PD-1 immunotherapy in non-Hodgkin’s lymphoma

Lin Yang, Qiuling Zhao, Ting Chen, Wenbin Liu, Xiuliang Qiu, Jincan Chen, Shengqiang Huang, Ruyi Huang, Liangliang Dong

Research

A novel angiogenesis-related scoring model predicts prognosis risk and treatment responsiveness in diffuse large B-cell lymphoma

Yu Liu, Jinhua Wang, Xiaochen Shen, Li Li, Ning Zhang, Xiaobo Wang, Bo Tang

Research

The role of comorbidity indices and histochemical markers in surgically resected and non-resected primary central nervous system lymphoma

Chia-En Wong, Wei-An Liao, Yu Chang, Po-Hsuan Lee, Chi-Chen Huang, Kung-Chao Chang, Jung-Shun Lee

Research

Thrombosis events in Chinese patients with newly diagnosed multiple myeloma

Panpan Li, Bei Xu, Jiadai Xu, Yawen Wang, Yang Yang, Wenjing Wang, Aiziguli Maihemaiti, Jing Li, Tianhong Xu, Liang Ren, Tianwei Lan, Chi Zhou, Pu Wang, Peng Liu

Research

Characterizing dry mass and volume changes in human multiple myeloma cells upon treatment with proteotoxic and genotoxic drugs

Xili Liu, Maria Moscvin, Seungeun Oh, Tianzeng Chen, Wonshik Choi, Benjamin Evans, Sean M. Rowell, Omar Nadeem, Clifton C. Mo, Adam S. Sperling, Kenneth C. Anderson, Zahid Yaqoob, Giada Bianchi, Yongjin Sung

Research

Multi-omics analysis of multiple myeloma patients with differential response to first-line treatment

Bo Zheng, Ke Yi, Yajun Zhang, Tongfang Pang, Jieyi Zhou, Jie He, Hongyan Lan, Hongming Xian, Rong Li

Research

In silico analysis of differentially expressed-aberrantly methylated genes in breast cancer for prognostic and therapeutic targets

Ashita Gadwal, Purvi Purohit, Manoj Khokhar, Jeewan Ram Vishnoi, Puneet Pareek, Ramkaran Choudhary, Poonam Elhence, Mithu Banerjee, Praveen Sharma

Open Access Research

Association of serum cortisol and cortisone levels and risk of recurrence after endocrine treatment in breast cancer

Feng Wang, Guro F. Giskeødegård, Sissel Skarra, Monica J. Engstrøm, Lars Hagen, Jürgen Geisler, Tomi S. Mikkola, Matti J. Tikkanen, Julia Debik, Randi J. Reidunsdatter, Tone F. Bathen

Open Access Research

Fecal levels of SCFA and BCFA during capecitabine in patients with metastatic or unresectable colorectal cancer

Janine Ziemons, Romy Aarnoutse, Anne Heuft, Lars Hillege, Janneke Waelen, Judith de Vos-Geelen, Liselot Valkenburg-van Iersel, Irene E. G. van Hellemond, Geert-Jan M. Creemers, Arnold Baars, Johanna H. M. J. Vestjens, John Penders, Koen Venema, Marjolein L. Smidt

Research

A meta-analysis of circulating tumor DNA as a survival indicator in small cell lung cancer patients

Jie Li, Liqun Wang, Zhouhuan Dong, Qi Song, Zhanbo Wang

Research

Pulmonary large cell neuroendocrine carcinoma (LCNEC): a population-based study addressing recent molecular-genetic advances and emerging therapeutic approaches

Jaffar Khan, Abdul Qahar Khan Yasinzai, Sabrina Matosz, Marjan Khan, Saleh Heneidi, Hector Mesa, Aman Chauhan, Jaydira Del Rivero, Nagla Abdel Karim, Asad Ullah

Research

Distribution and survival outcomes of primary head and neck hematolymphoid neoplasms in older people: a population-based study

Yan-Hua Zheng, Biao Tian, Wei-Wei Qin, Qing-Wen Zhu, Juan Feng, Wu-Yue Hu, Ren-An Chen, Li Liu

Research

Research in the genetics of pheochromocytoma and paraganglioma: a bibliometric analysis from 2002 to 2022

Lei Li, Lihua Guan, Yueming Tang, Yutong Zou, Jian Zhong, Ling Qiu

Open Access Research

Survival impact of immediate complete lymph node dissection for Chinese acral and cutaneous melanoma with micrometastasis in sentinel nodes: a retrospective study

Jingqin Zhong, Zijian Zou, Tu Hu, Wei Sun, Chunmeng Wang, Wangjun Yan, Zhiguo Luo, Xin Liu, Yu Xu, Yong Chen

Research

Combination of vonoprazan and amoxicillin as the first-line Helicobacter pylori eradication therapy: a multicenter, prospective, randomized, parallel-controlled study

Xiang Peng, Huang-wei Chen, Yu Wan, Pei-zhu Su, Jing Yu, Jun-jun Liu, Yi Lu, Min Zhang, Jia-Yin Yao, Min Zhi

Correspondence

Side effects of COVID-19 vaccination and breast cancer

Amnuay Kleebayoon, Viroj Wiwanitkit

Correspondence

Reduction in Rubicon by cigarette smoke is associated with impaired phagocytosis and occurs through lysosomal degradation pathway

Patrick F. Asare, Plinio R. Hurtado, Hai B. Tran, Griffith B. Perkins, Eugene Roscioli, Sandra Hodge

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Erhebliches Risiko für Kehlkopfkrebs bei mäßiger Dysplasie

29.05.2024 Larynxkarzinom Nachrichten

Fast ein Viertel der Personen mit mäßig dysplastischen Stimmlippenläsionen entwickelt einen Kehlkopftumor. Solche Personen benötigen daher eine besonders enge ärztliche Überwachung.

Nach Herzinfarkt mit Typ-1-Diabetes schlechtere Karten als mit Typ 2?

29.05.2024 Herzinfarkt Nachrichten

Bei Menschen mit Typ-2-Diabetes sind die Chancen, einen Myokardinfarkt zu überleben, in den letzten 15 Jahren deutlich gestiegen – nicht jedoch bei Betroffenen mit Typ 1.

15% bedauern gewählte Blasenkrebs-Therapie

29.05.2024 Urothelkarzinom Nachrichten

Ob Patienten und Patientinnen mit neu diagnostiziertem Blasenkrebs ein Jahr später Bedauern über die Therapieentscheidung empfinden, wird einer Studie aus England zufolge von der Radikalität und dem Erfolg des Eingriffs beeinflusst.

Costims – das nächste heiße Ding in der Krebstherapie?

28.05.2024 Onkologische Immuntherapie Nachrichten

„Kalte“ Tumoren werden heiß – CD28-kostimulatorische Antikörper sollen dies ermöglichen. Am besten könnten diese in Kombination mit BiTEs und Checkpointhemmern wirken. Erste klinische Studien laufen bereits.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.