Erschienen in:
01.06.2006 | ORIGINAL CONTRIBUTION
Current comorbidity among consecutive adolescent psychiatric outpatients with DSM-IV mood disorders
verfasst von:
Linnea Karlsson, MD, PhD, Mirjami Pelkonen, Phd, Titta Ruuttu, MA, Olli Kiviruusu, BSocSc, Hannele Heilä, MD, PhD, Matti Holi, MD, PhD, Kirsi Kettunen, MD, Virpi Tuisku, MSocSc, Annamari Tuulio-Henriksson, PhD, Johanna Törrönen, MD, Mauri Marttunen, MD, PhD
Erschienen in:
European Child & Adolescent Psychiatry
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Ausgabe 4/2006
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Abstract
Objective
To compare selected characteristics (age, sex, age of onset for depression, impairment, severity of depression, somatic comorbidity, and treatment status) of adolescents with currently comorbid and non-comorbid depression.
Method
A sample of 218 consecutive adolescent (13–19 years) psychiatric outpatients with depressive disorders, and 200 age- and sex-matched school-attending controls were interviewed for DSM-IV Axis I and Axis II diagnoses.
Results
Current comorbidity, most commonly with anxiety disorders, was equally frequent (>70%) in outpatients and depressed controls. Younger age (OR 0.20; 95% CI 0.08, 0.51) and male gender (OR 0.02; 95% CI 0.09, 0.55) were associated with concurrent disruptive disorders. Current comorbidity with substance use disorders (SUD) was independent of age (OR 1.13; 95% CI 0.51, 2.49) and sex (OR 0.51; 95% CI 0.22, 1.17). Personality disorders associated with older age (OR 2.06; 95% CI 1.10, 3.86). In multivariable logistic regression analysis, impairment (GAF ≤60) was associated with current comorbidity (OR 3.13; 95% CI 1.53, 6.45), while severity of depression and lifetime age of onset for depression were not.
Conclusions
Adolescent depression presents with age- and sex-dependent patterns of multiple co-occurring problem areas. While many clinical characteristics of adolescent depression are not affected by comorbidity, comorbidity associates with increased impairment.