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Erschienen in: Der Urologe 7/2014

01.07.2014 | Leitthema

Die radikale Prostatektomie

Intra- und postoperative Komplikationen erkennen und behandeln

verfasst von: Dr. M. Saar, C.H. Ohlmann, M. Janssen, M. Stöckle, S. Siemer

Erschienen in: Die Urologie | Ausgabe 7/2014

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Zusammenfassung

Die chirurgische Entfernung der Prostata mittels radikaler Prostatektomie ist für das organbegrenzte Prostatakarzinom das häufigste Therapieverfahren. Der Eingriff gewährleistet bei komplikationslosem Verlauf eine komplette Entfernung des Tumorgewebes und somit vollständige Heilung des Patienten. Die Operationsmethoden wurden in den letzten Jahrzehnten stetig modernisiert und die Invasivität durch neue Technologien reduziert. Des Weiteren konnte ein optimiertes perioperatives Management die Hospitalisationszeit verkürzen. In diesem Zusammenhang ist das frühzeitige Erkennen intraoperativer und postoperativer Komplikationen von großer Relevanz, um die regelhafte Genesung des Patienten nicht zu gefährden. In diesem Artikel werden die verschiedenen Komplikationsmöglichkeiten während und nach der Operation beschrieben und mögliche Lösungsansätze aufgezeigt.
Literatur
1.
Zurück zum Zitat Andonian S, Okeke Z, Okeke DA et al (2008) Device failures associated with patient injuries during robot-assisted laparoscopic surgeries: a comprehensive review of FDA MAUDE database. Can J Urol 15:3912–3916PubMed Andonian S, Okeke Z, Okeke DA et al (2008) Device failures associated with patient injuries during robot-assisted laparoscopic surgeries: a comprehensive review of FDA MAUDE database. Can J Urol 15:3912–3916PubMed
2.
Zurück zum Zitat Anheuser P, Treiyer A, Stark E et al (2010) Lymphoceles after radical retropubic prostatectomy. A treatment algorithm. Urologe A 49:832–836PubMedCrossRef Anheuser P, Treiyer A, Stark E et al (2010) Lymphoceles after radical retropubic prostatectomy. A treatment algorithm. Urologe A 49:832–836PubMedCrossRef
3.
Zurück zum Zitat Augustin H, Hammerer P, Graefen M et al (2003) Intraoperative and perioperative morbidity of contemporary radical retropubic prostatectomy in a consecutive series of 1243 patients: results of a single center between 1999 and 2002. Eur Urol 43:113–118PubMedCrossRef Augustin H, Hammerer P, Graefen M et al (2003) Intraoperative and perioperative morbidity of contemporary radical retropubic prostatectomy in a consecutive series of 1243 patients: results of a single center between 1999 and 2002. Eur Urol 43:113–118PubMedCrossRef
4.
Zurück zum Zitat Badani KK, Kaul S, Menon M (2007) Evolution of robotic radical prostatectomy: assessment after 2766 procedures. Cancer 110:1951–1958PubMedCrossRef Badani KK, Kaul S, Menon M (2007) Evolution of robotic radical prostatectomy: assessment after 2766 procedures. Cancer 110:1951–1958PubMedCrossRef
5.
Zurück zum Zitat Bill-Axelson A, Holmberg L, Filen F et al (2008) Radical prostatectomy versus watchful waiting in localized prostate cancer: the Scandinavian prostate cancer group-4 randomized trial. J Natl Cancer Inst 100:1144–1154PubMedCentralPubMedCrossRef Bill-Axelson A, Holmberg L, Filen F et al (2008) Radical prostatectomy versus watchful waiting in localized prostate cancer: the Scandinavian prostate cancer group-4 randomized trial. J Natl Cancer Inst 100:1144–1154PubMedCentralPubMedCrossRef
6.
Zurück zum Zitat Catalona WJ, Carvalhal GF, Mager DE et al (1999) Potency, continence and complication rates in 1,870 consecutive radical retropubic prostatectomies. J Urol 162:433–438PubMedCrossRef Catalona WJ, Carvalhal GF, Mager DE et al (1999) Potency, continence and complication rates in 1,870 consecutive radical retropubic prostatectomies. J Urol 162:433–438PubMedCrossRef
7.
Zurück zum Zitat Challacombe B, Dasgupta P (2007) Reconstruction of the lower urinary tract by laparoscopic and robotic surgery. Curr Opin Urol 17:390–395PubMedCrossRef Challacombe B, Dasgupta P (2007) Reconstruction of the lower urinary tract by laparoscopic and robotic surgery. Curr Opin Urol 17:390–395PubMedCrossRef
8.
Zurück zum Zitat Dillioglugil O, Leibman BD, Leibman NS et al (1997) Risk factors for complications and morbidity after radical retropubic prostatectomy. J Urol 157:1760–1767PubMedCrossRef Dillioglugil O, Leibman BD, Leibman NS et al (1997) Risk factors for complications and morbidity after radical retropubic prostatectomy. J Urol 157:1760–1767PubMedCrossRef
9.
Zurück zum Zitat Ficarra V, Novara G, Artibani W et al (2009) Retropubic, laparoscopic, and robot-assisted radical prostatectomy: a systematic review and cumulative analysis of comparative studies. Eur Urol 55:1037–1063PubMedCrossRef Ficarra V, Novara G, Artibani W et al (2009) Retropubic, laparoscopic, and robot-assisted radical prostatectomy: a systematic review and cumulative analysis of comparative studies. Eur Urol 55:1037–1063PubMedCrossRef
10.
Zurück zum Zitat Gillitzer R, Melchior SW, Hampel C et al (2004) Specific complications of radical perineal prostatectomy: a single institution study of more than 600 cases. J Urol 172:124–128PubMedCrossRef Gillitzer R, Melchior SW, Hampel C et al (2004) Specific complications of radical perineal prostatectomy: a single institution study of more than 600 cases. J Urol 172:124–128PubMedCrossRef
11.
Zurück zum Zitat Groenman FA, Peters LW, Rademaker BM et al (2008) Embolism of air and gas in hysteroscopic procedures: pathophysiology and implication for daily practice. J Min Invas Gynecol 15:241–247CrossRef Groenman FA, Peters LW, Rademaker BM et al (2008) Embolism of air and gas in hysteroscopic procedures: pathophysiology and implication for daily practice. J Min Invas Gynecol 15:241–247CrossRef
12.
Zurück zum Zitat Guillonneau B, Gupta R, El Fettouh H et al (2003) Laparoscopic [correction of laproscopic] management of rectal injury during laparoscopic [correction of laproscopic] radical prostatectomy. J Urol 169:1694–1696PubMedCrossRef Guillonneau B, Gupta R, El Fettouh H et al (2003) Laparoscopic [correction of laproscopic] management of rectal injury during laparoscopic [correction of laproscopic] radical prostatectomy. J Urol 169:1694–1696PubMedCrossRef
13.
Zurück zum Zitat Guillonneau B, Rozet F, Cathelineau X et al (2002) Perioperative complications of laparoscopic radical prostatectomy: the Montsouris 3-year experience. J Urol 167:51–56PubMedCrossRef Guillonneau B, Rozet F, Cathelineau X et al (2002) Perioperative complications of laparoscopic radical prostatectomy: the Montsouris 3-year experience. J Urol 167:51–56PubMedCrossRef
14.
Zurück zum Zitat Harlan LC, Potosky A, Gilliland FD et al (2001) Factors associated with initial therapy for clinically localized prostate cancer: prostate cancer outcomes study. J Natl Cancer Inst 93:1864–1871PubMedCrossRef Harlan LC, Potosky A, Gilliland FD et al (2001) Factors associated with initial therapy for clinically localized prostate cancer: prostate cancer outcomes study. J Natl Cancer Inst 93:1864–1871PubMedCrossRef
15.
Zurück zum Zitat Hu JC, Gold KF, Pashos CL et al (2003) Role of surgeon volume in radical prostatectomy outcomes. J Clin Oncol 21:401–405PubMedCrossRef Hu JC, Gold KF, Pashos CL et al (2003) Role of surgeon volume in radical prostatectomy outcomes. J Clin Oncol 21:401–405PubMedCrossRef
16.
Zurück zum Zitat Hu JC, Nelson RA, Wilson TG et al (2006) Perioperative complications of laparoscopic and robotic assisted laparoscopic radical prostatectomy. J Urol 175:541–546PubMedCrossRef Hu JC, Nelson RA, Wilson TG et al (2006) Perioperative complications of laparoscopic and robotic assisted laparoscopic radical prostatectomy. J Urol 175:541–546PubMedCrossRef
17.
Zurück zum Zitat Hu JC, Wang Q, Pashos CL et al (2008) Utilization and outcomes of minimally invasive radical prostatectomy. J Clin Oncol 26:2278–2284PubMedCrossRef Hu JC, Wang Q, Pashos CL et al (2008) Utilization and outcomes of minimally invasive radical prostatectomy. J Clin Oncol 26:2278–2284PubMedCrossRef
18.
Zurück zum Zitat Jhaveri JK, Penna FJ, Diaz-Insua M et al (2014) Ureteral injuries sustained during robot-assisted radical prostatectomy. J Endurol 28:318–324CrossRef Jhaveri JK, Penna FJ, Diaz-Insua M et al (2014) Ureteral injuries sustained during robot-assisted radical prostatectomy. J Endurol 28:318–324CrossRef
19.
Zurück zum Zitat Khemees TA, Novak R, Abaza R (2013) Risk and prevention of acute urinary retention after robotic prostatectomy. J Urol 189:1432–1436PubMedCrossRef Khemees TA, Novak R, Abaza R (2013) Risk and prevention of acute urinary retention after robotic prostatectomy. J Urol 189:1432–1436PubMedCrossRef
20.
Zurück zum Zitat Khoder WY, Trottmann M, Buchner A et al (2011) Risk factors for pelvic lymphoceles post-radical prostatectomy. Int J Urol 18:638–643PubMed Khoder WY, Trottmann M, Buchner A et al (2011) Risk factors for pelvic lymphoceles post-radical prostatectomy. Int J Urol 18:638–643PubMed
21.
Zurück zum Zitat Lance RS, Freidrichs PA, Kane C et al (2001) A comparison of radical retropubic with perineal prostatectomy for localized prostate cancer within the Uniformed Services Urology Research Group. BJU Int 87:61–65PubMedCrossRef Lance RS, Freidrichs PA, Kane C et al (2001) A comparison of radical retropubic with perineal prostatectomy for localized prostate cancer within the Uniformed Services Urology Research Group. BJU Int 87:61–65PubMedCrossRef
22.
Zurück zum Zitat Lavery HJ, Thaly R, Albala D et al (2008) Robotic equipment malfunction during robotic prostatectomy: a multi-institutional study. J Endurol 22:2165–2168CrossRef Lavery HJ, Thaly R, Albala D et al (2008) Robotic equipment malfunction during robotic prostatectomy: a multi-institutional study. J Endurol 22:2165–2168CrossRef
23.
Zurück zum Zitat Lee DK, Montgomery DP, Porter JR (2013) Concurrent transperitoneal repair for incidentally detected inguinal hernias during robotically assisted radical prostatectomy. Urology 82:1320–1322PubMedCrossRef Lee DK, Montgomery DP, Porter JR (2013) Concurrent transperitoneal repair for incidentally detected inguinal hernias during robotically assisted radical prostatectomy. Urology 82:1320–1322PubMedCrossRef
24.
Zurück zum Zitat Lepor H, Kaci L (2003) Contemporary evaluation of operative parameters and complications related to open radical retropubic prostatectomy. Urology 62:702–706PubMedCrossRef Lepor H, Kaci L (2003) Contemporary evaluation of operative parameters and complications related to open radical retropubic prostatectomy. Urology 62:702–706PubMedCrossRef
25.
Zurück zum Zitat Lepor H, Nieder AM, Ferrandino MN (2001) Intraoperative and postoperative complications of radical retropubic prostatectomy in a consecutive series of 1,000 cases. J Urol 166:1729–1733PubMedCrossRef Lepor H, Nieder AM, Ferrandino MN (2001) Intraoperative and postoperative complications of radical retropubic prostatectomy in a consecutive series of 1,000 cases. J Urol 166:1729–1733PubMedCrossRef
26.
Zurück zum Zitat Liatsikos E, Rabenalt R, Burchardt M et al (2008) Prevention and management of perioperative complications in laparoscopic and endoscopic radical prostatectomy. World J Urol 26:571–580PubMedCrossRef Liatsikos E, Rabenalt R, Burchardt M et al (2008) Prevention and management of perioperative complications in laparoscopic and endoscopic radical prostatectomy. World J Urol 26:571–580PubMedCrossRef
27.
Zurück zum Zitat Loppenberg B, Noldus J, Palisaar J (2011) Complications of radical retropubic prostatectomies based on the Martin criteria. Urologe A 50:1403–1411PubMedCrossRef Loppenberg B, Noldus J, Palisaar J (2011) Complications of radical retropubic prostatectomies based on the Martin criteria. Urologe A 50:1403–1411PubMedCrossRef
28.
Zurück zum Zitat Menon M, Tewari A, Baize B et al (2002) Prospective comparison of radical retropubic prostatectomy and robot-assisted anatomic prostatectomy: the Vattikuti Urology Institute experience. Urology 60:864–868PubMedCrossRef Menon M, Tewari A, Baize B et al (2002) Prospective comparison of radical retropubic prostatectomy and robot-assisted anatomic prostatectomy: the Vattikuti Urology Institute experience. Urology 60:864–868PubMedCrossRef
29.
Zurück zum Zitat Mitropoulos D, Artibani W, Graefen M et al (2012) Reporting and grading of complications after urologic surgical procedures: an ad hoc EAU guidelines panel assessment and recommendations. Eur Urol 61:341–349PubMedCrossRef Mitropoulos D, Artibani W, Graefen M et al (2012) Reporting and grading of complications after urologic surgical procedures: an ad hoc EAU guidelines panel assessment and recommendations. Eur Urol 61:341–349PubMedCrossRef
30.
Zurück zum Zitat Montorsi F, Wilson TG, Rosen RC et al (2012) Best practices in robot-assisted radical prostatectomy: recommendations of the Pasadena Consensus Panel. Eur Urol 62:368–381PubMedCrossRef Montorsi F, Wilson TG, Rosen RC et al (2012) Best practices in robot-assisted radical prostatectomy: recommendations of the Pasadena Consensus Panel. Eur Urol 62:368–381PubMedCrossRef
31.
Zurück zum Zitat Mottrie A, Ficarra V (2010) Can robot-assisted radical prostatectomy still be considered a new technology pushed by marketers? The IDEAL evaluation. Eur Urol 58:525–527PubMedCrossRef Mottrie A, Ficarra V (2010) Can robot-assisted radical prostatectomy still be considered a new technology pushed by marketers? The IDEAL evaluation. Eur Urol 58:525–527PubMedCrossRef
32.
Zurück zum Zitat Murphy DG, Bjartell A, Ficarra V et al (2010) Downsides of robot-assisted laparoscopic radical prostatectomy: limitations and complications. Eur Urol 57:735–746PubMedCrossRef Murphy DG, Bjartell A, Ficarra V et al (2010) Downsides of robot-assisted laparoscopic radical prostatectomy: limitations and complications. Eur Urol 57:735–746PubMedCrossRef
33.
Zurück zum Zitat Nam RK, Cheung P, Herschorn S et al (2014) Incidence of complications other than urinary incontinence or erectile dysfunction after radical prostatectomy or radiotherapy for prostate cancer: a population-based cohort study. Lancet Oncol 15:223–231PubMedCrossRef Nam RK, Cheung P, Herschorn S et al (2014) Incidence of complications other than urinary incontinence or erectile dysfunction after radical prostatectomy or radiotherapy for prostate cancer: a population-based cohort study. Lancet Oncol 15:223–231PubMedCrossRef
34.
Zurück zum Zitat Patel VR, Sivaraman A, Coelho RF et al (2011) Pentafecta: a new concept for reporting outcomes of robot-assisted laparoscopic radical prostatectomy. Eur Urol 59:702–707PubMedCrossRef Patel VR, Sivaraman A, Coelho RF et al (2011) Pentafecta: a new concept for reporting outcomes of robot-assisted laparoscopic radical prostatectomy. Eur Urol 59:702–707PubMedCrossRef
35.
Zurück zum Zitat Rabbani F, Yunis LH, Pinochet R et al (2010) Comprehensive standardized report of complications of retropubic and laparoscopic radical prostatectomy. Eur Urol 57:371–386PubMedCrossRef Rabbani F, Yunis LH, Pinochet R et al (2010) Comprehensive standardized report of complications of retropubic and laparoscopic radical prostatectomy. Eur Urol 57:371–386PubMedCrossRef
36.
Zurück zum Zitat Rassweiler J, Hruza M, Teber D et al (2006) Laparoscopic and robotic assisted radical prostatectomy – critical analysis of the results. Eur Urol 49:612–624PubMedCrossRef Rassweiler J, Hruza M, Teber D et al (2006) Laparoscopic and robotic assisted radical prostatectomy – critical analysis of the results. Eur Urol 49:612–624PubMedCrossRef
37.
Zurück zum Zitat Swindle P, Eastham JA, Ohori M et al (2005) Do margins matter? The prognostic significance of positive surgical margins in radical prostatectomy specimens. J Urol 174:903–907PubMedCrossRef Swindle P, Eastham JA, Ohori M et al (2005) Do margins matter? The prognostic significance of positive surgical margins in radical prostatectomy specimens. J Urol 174:903–907PubMedCrossRef
38.
Zurück zum Zitat Teber D, Gozen AS, Cresswell J et al (2009) Prevention and management of ureteral injuries occurring during laparoscopic radical prostatectomy: the Heilbronn experience and a review of the literature. World J Urol 27:613–618PubMedCrossRef Teber D, Gozen AS, Cresswell J et al (2009) Prevention and management of ureteral injuries occurring during laparoscopic radical prostatectomy: the Heilbronn experience and a review of the literature. World J Urol 27:613–618PubMedCrossRef
39.
Zurück zum Zitat Tewari A, Sooriakumaran P, Bloch DA et al (2012) Positive surgical margin and perioperative complication rates of primary surgical treatments for prostate cancer: a systematic review and meta-analysis comparing retropubic, laparoscopic, and robotic prostatectomy. Eur Urol 62:1–15PubMedCrossRef Tewari A, Sooriakumaran P, Bloch DA et al (2012) Positive surgical margin and perioperative complication rates of primary surgical treatments for prostate cancer: a systematic review and meta-analysis comparing retropubic, laparoscopic, and robotic prostatectomy. Eur Urol 62:1–15PubMedCrossRef
40.
Zurück zum Zitat Touijer K, Eastham JA, Secin FP et al (2008) Comprehensive prospective comparative analysis of outcomes between open and laparoscopic radical prostatectomy conducted in 2003 to 2005. J Urol 179:1811–1817PubMedCentralPubMedCrossRef Touijer K, Eastham JA, Secin FP et al (2008) Comprehensive prospective comparative analysis of outcomes between open and laparoscopic radical prostatectomy conducted in 2003 to 2005. J Urol 179:1811–1817PubMedCentralPubMedCrossRef
41.
Zurück zum Zitat Trinh QD, Sammon J, Sun M et al (2012) Perioperative outcomes of robot-assisted radical prostatectomy compared with open radical prostatectomy: results from the nationwide inpatient sample. Eur Urol 61:679–685PubMedCrossRef Trinh QD, Sammon J, Sun M et al (2012) Perioperative outcomes of robot-assisted radical prostatectomy compared with open radical prostatectomy: results from the nationwide inpatient sample. Eur Urol 61:679–685PubMedCrossRef
42.
Zurück zum Zitat Tyritzis SI, Katafigiotis I, Constantinides CA (2012) All you need to know about urethrovesical anastomotic urinary leakage following radical prostatectomy. J Urol 188:369–376PubMedCrossRef Tyritzis SI, Katafigiotis I, Constantinides CA (2012) All you need to know about urethrovesical anastomotic urinary leakage following radical prostatectomy. J Urol 188:369–376PubMedCrossRef
43.
Zurück zum Zitat Van Hemelrijck M, Garmo H, Holmberg L et al (2013) Thromboembolic events following surgery for prostate cancer. Eur Urol 63:354–363CrossRef Van Hemelrijck M, Garmo H, Holmberg L et al (2013) Thromboembolic events following surgery for prostate cancer. Eur Urol 63:354–363CrossRef
44.
Zurück zum Zitat Wedmid A, Mendoza P, Sharma S et al (2011) Rectal injury during robot-assisted radical prostatectomy: incidence and management. J Urol 186:1928–1933PubMedCrossRef Wedmid A, Mendoza P, Sharma S et al (2011) Rectal injury during robot-assisted radical prostatectomy: incidence and management. J Urol 186:1928–1933PubMedCrossRef
45.
Zurück zum Zitat Weldon VE, Tavel FR, Neuwirth H (1997) Continence, potency and morbidity after radical perineal prostatectomy. J Urol 158:1470–1475PubMedCrossRef Weldon VE, Tavel FR, Neuwirth H (1997) Continence, potency and morbidity after radical perineal prostatectomy. J Urol 158:1470–1475PubMedCrossRef
46.
Zurück zum Zitat Wen T, Deibert CM, Siringo F et al (2014) Positioning-related complications of minimally-invasive radical prostatectomies. J Endourol 28(4):481–486CrossRef Wen T, Deibert CM, Siringo F et al (2014) Positioning-related complications of minimally-invasive radical prostatectomies. J Endourol 28(4):481–486CrossRef
47.
Zurück zum Zitat Zhu S, Zhang H, Xie L et al (2013) Risk factors and prevention of inguinal hernia after radical prostatectomy: a systematic review and meta-analysis. J Urol 189:884–890PubMedCrossRef Zhu S, Zhang H, Xie L et al (2013) Risk factors and prevention of inguinal hernia after radical prostatectomy: a systematic review and meta-analysis. J Urol 189:884–890PubMedCrossRef
Metadaten
Titel
Die radikale Prostatektomie
Intra- und postoperative Komplikationen erkennen und behandeln
verfasst von
Dr. M. Saar
C.H. Ohlmann
M. Janssen
M. Stöckle
S. Siemer
Publikationsdatum
01.07.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
Die Urologie / Ausgabe 7/2014
Print ISSN: 2731-7064
Elektronische ISSN: 2731-7072
DOI
https://doi.org/10.1007/s00120-014-3500-x

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