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Erschienen in: European Journal of Nutrition 3/2015

01.04.2015 | Original Contribution

Dietary glycemic index, glycemic load and risk of age-related cataract extraction: a case–control study in Italy

verfasst von: Federica Turati, Maria Filomeno, Carlotta Galeone, Diego Serraino, Ettore Bidoli, Carlo La Vecchia

Erschienen in: European Journal of Nutrition | Ausgabe 3/2015

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Abstract

Purpose

Although a role of glycemic index (GI) and glycemic load (GL) in age-related cataract development is plausible, a few studies, all conducted in USA or Australia, provided results on this issue. The aim of the present study was to provide new original data from a Mediterranean population.

Methods

We analyzed data from an Italian case–control study including 761 cases with cataract extraction and 1,522 hospital controls, frequency-matched with cases by center, sex, and age. Multivariate odds ratios (ORs) for GI and GL intakes were obtained from logistic regression models after allowance for major confounding factors, including non carbohydrate energy intake, smoking, and diabetes.

Results

The ORs of cataract extraction for the highest versus the lowest tertile were 1.20 (95 % confidence interval, CI 0.91–1.57) for GI and 1.57 (95 % CI 1.16–2.13) for GL, with a statistically significant trend in risk for GL (p < 0.01). Results were materially unchanged when diabetics were excluded from the analysis. No heterogeneity emerged across strata of sex, age, education, smoking habits and body mass index.

Conclusions

The present study supports a positive association between dietary GL and the risk of cataract extraction, independently from diabetes, and a lack of association for GI.
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Metadaten
Titel
Dietary glycemic index, glycemic load and risk of age-related cataract extraction: a case–control study in Italy
verfasst von
Federica Turati
Maria Filomeno
Carlotta Galeone
Diego Serraino
Ettore Bidoli
Carlo La Vecchia
Publikationsdatum
01.04.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Nutrition / Ausgabe 3/2015
Print ISSN: 1436-6207
Elektronische ISSN: 1436-6215
DOI
https://doi.org/10.1007/s00394-014-0731-y

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