Skip to main content
Erschienen in: European Journal of Nutrition 6/2015

01.09.2015 | Original Contribution

Impact of removing iodized salt on the iodine nutrition of children living in areas with variable iodine content in drinking water

verfasst von: Shengmin Lv, Yinglu Zhao, Yanxia Li, Yuchun Wang, Hua Liu, Yang Li, Jun Zhao, Shannon Rutherford

Erschienen in: European Journal of Nutrition | Ausgabe 6/2015

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Excess iodine in drinking water has emerged as a public health issue in China. This study assesses the effectiveness of removing iodized salt on reducing the iodine excess in populations living in high-iodine areas and also to identify the threshold value for safe levels of iodine in water.

Methods

Twelve villages from 5 cities of Hebei Province with iodine content in drinking water ranging from 39 to 313 µg/l were selected to compare the urinary iodine content of children aged 8–10 years before and after removing iodized salt from their diet.

Results

For 3 villages where median water iodine content (MWIC) was below 110 µg/l, following the removal of iodized salt (the intervention), the median urinary iodine content (MUIC) reduced to under 300 µg/l decreasing from 365, 380, 351 to 247, 240, 281 µg/l, respectively. However, the MUIC in the 9 villages with MWIC above 110 µg/l remained higher than 300 µg/l. The children’s MUIC correlated positively with the MWIC in the 12 villages (p ≤ 0.001). The linear regression equation after removing iodized salt was MUIC = 0.6761MWIC + 225.67, indicating that to keep the MUIC below 300 µg/l (the iodine excess threshold recommended by the WHO) requires the MWIC to be under 110 µg/l.

Conclusion

Removing iodized salt could only correct the iodine excess in the population living in the areas with MWIC below 110 µg/l. In the areas with water iodine above 110 µg/l, interventions should be focused on seeking water with lower iodine content. This study suggests a threshold value of 110 µg/l of iodine in drinking water to maintain a safe level of dietary iodine.
Literatur
1.
Zurück zum Zitat Lv SM, Xie LJ, Zhou RH et al (2009) Control of iodine deficiency disorders following 10-year universal salt iodization in Hebei province of China. Biomed Environ Sci 22:472–479CrossRef Lv SM, Xie LJ, Zhou RH et al (2009) Control of iodine deficiency disorders following 10-year universal salt iodization in Hebei province of China. Biomed Environ Sci 22:472–479CrossRef
2.
Zurück zum Zitat Yu ZH, Zhu HM, Chen CY et al (1999) Proceedings on endemic goiter induced by high iodine. Chin J Endem 18:301–305 (in Chinese) Yu ZH, Zhu HM, Chen CY et al (1999) Proceedings on endemic goiter induced by high iodine. Chin J Endem 18:301–305 (in Chinese)
3.
Zurück zum Zitat Ministry of Health (2003) National criteria for classifying high iodine regions. MOH, Beijing Ministry of Health (2003) National criteria for classifying high iodine regions. MOH, Beijing
4.
Zurück zum Zitat Zhao JK, Chen ZP, Maberly G (1998) Iodine-rich drinking water of natural origin in China. Lancet 352:2024CrossRef Zhao JK, Chen ZP, Maberly G (1998) Iodine-rich drinking water of natural origin in China. Lancet 352:2024CrossRef
5.
Zurück zum Zitat Shen HM, Liu SJ, Sun DJ et al (2011) Geographical distribution of drinking-water with high iodine level and association between high iodine level in drinking-water and goitre: a Chinese national investigation. Br J Nutr 106:243–247CrossRef Shen HM, Liu SJ, Sun DJ et al (2011) Geographical distribution of drinking-water with high iodine level and association between high iodine level in drinking-water and goitre: a Chinese national investigation. Br J Nutr 106:243–247CrossRef
6.
Zurück zum Zitat Burgi H (2010) Iodine excess. Best Pract Res Clin Endoc Met 25:107–115CrossRef Burgi H (2010) Iodine excess. Best Pract Res Clin Endoc Met 25:107–115CrossRef
7.
Zurück zum Zitat Wang Y, Zheng HM, Wang CG et al (2005) Epidemiological investigation on water-sourced high level iodine goiter in Yellow river delta in Henan province. Chin J Endem 23:231–233 (in Chinese) Wang Y, Zheng HM, Wang CG et al (2005) Epidemiological investigation on water-sourced high level iodine goiter in Yellow river delta in Henan province. Chin J Endem 23:231–233 (in Chinese)
8.
Zurück zum Zitat Zhang XD, Jia QZ, Wang ZH et al (2007) Epidemiological survey of inland water- borne high iodine in drinking water in Shanxi Province. Chin Tropl Med 17:679–681 (in Chinese) Zhang XD, Jia QZ, Wang ZH et al (2007) Epidemiological survey of inland water- borne high iodine in drinking water in Shanxi Province. Chin Tropl Med 17:679–681 (in Chinese)
9.
Zurück zum Zitat Zhang ZZ, Fan J, Guo HY et al (2007) Distribution and goiter status of areas with high iodine in Inner Mongolia. J Baotou Med 23:566–568 (in Chinese) Zhang ZZ, Fan J, Guo HY et al (2007) Distribution and goiter status of areas with high iodine in Inner Mongolia. J Baotou Med 23:566–568 (in Chinese)
10.
Zurück zum Zitat Lv S, Xu D, Wang Y et al (2014) Goitre prevalence and epidemiological features in children living in areas with mildly excessive iodine in drinking-water. Br J Nutr 111:186–192CrossRef Lv S, Xu D, Wang Y et al (2014) Goitre prevalence and epidemiological features in children living in areas with mildly excessive iodine in drinking-water. Br J Nutr 111:186–192CrossRef
11.
Zurück zum Zitat WHO/UNICEF/ICCIDD (2007) Assessment of iodine deficiency disorders and monitoring their elimination, 3rd ed. WHO, Geneva WHO/UNICEF/ICCIDD (2007) Assessment of iodine deficiency disorders and monitoring their elimination, 3rd ed. WHO, Geneva
12.
Zurück zum Zitat Lv SM, Zhao J, Xu D et al (2012) An epidemiological survey of children’s iodine nutrition and goitre status in regions with mildly excessive iodine in drinking water in Hebei Province, China. Public Health Nutr 15:1168–1173CrossRef Lv SM, Zhao J, Xu D et al (2012) An epidemiological survey of children’s iodine nutrition and goitre status in regions with mildly excessive iodine in drinking water in Hebei Province, China. Public Health Nutr 15:1168–1173CrossRef
13.
Zurück zum Zitat Pino S, Fang SL, Braverman LE (1998) Ammonium persulfate: a new and safe method for measuring urinary iodine by ammonium persulfate oxidation. Exp Clin Endocrinol Diabetes 106(Suppl 3):S22–S27CrossRef Pino S, Fang SL, Braverman LE (1998) Ammonium persulfate: a new and safe method for measuring urinary iodine by ammonium persulfate oxidation. Exp Clin Endocrinol Diabetes 106(Suppl 3):S22–S27CrossRef
14.
Zurück zum Zitat United Nations Children’s Fund (UNICEF) ROSCA (1998) The use of iodised salt in the prevention of iodine deficiency disorders—a handbook of monitoring and quality control. UNICEF ROSCA, New Delhi United Nations Children’s Fund (UNICEF) ROSCA (1998) The use of iodised salt in the prevention of iodine deficiency disorders—a handbook of monitoring and quality control. UNICEF ROSCA, New Delhi
15.
Zurück zum Zitat Ministry of Health (2007) National surveillance plan for iodine deficiency disorders. MOH, Beijing (in Chinese) Ministry of Health (2007) National surveillance plan for iodine deficiency disorders. MOH, Beijing (in Chinese)
16.
Zurück zum Zitat Ministry of Health (2006) The standard test method for drinking water. MOH, Beijing (in Chinese) Ministry of Health (2006) The standard test method for drinking water. MOH, Beijing (in Chinese)
17.
Zurück zum Zitat Guo XW, Qin QL, Liu CJ et al (2007) Study on iodine nutritional status of target population due to different iodine concentrations in drinking water after stopping iodized salt. J Hyg Res 36:427–431 (in Chinese) Guo XW, Qin QL, Liu CJ et al (2007) Study on iodine nutritional status of target population due to different iodine concentrations in drinking water after stopping iodized salt. J Hyg Res 36:427–431 (in Chinese)
18.
Zurück zum Zitat Li SM, Zhang GH, Gu YY et al (2009) Study on changing of iodine nutrition level of the people with unexcessive iodine drinking water in iodine excess area s after stopping supplies of iodized salt. Chin J Ctrl Endem Dis 24:107–109 (in Chinese) Li SM, Zhang GH, Gu YY et al (2009) Study on changing of iodine nutrition level of the people with unexcessive iodine drinking water in iodine excess area s after stopping supplies of iodized salt. Chin J Ctrl Endem Dis 24:107–109 (in Chinese)
19.
Zurück zum Zitat Lv SM, Wang YC, Xu D et al (2013) Drinking water contributes to excessive iodine intake among children in Hebei, China. Eur J Clin Nutr 67:961–965CrossRef Lv SM, Wang YC, Xu D et al (2013) Drinking water contributes to excessive iodine intake among children in Hebei, China. Eur J Clin Nutr 67:961–965CrossRef
20.
Zurück zum Zitat Guo XW, Qin QL, Chen ZP et al (2007) Iodine nutrition status of population in the areas with different iodine concentrations of drinking water. Acta Nutr Sin 29:526–530 (in Chinese) Guo XW, Qin QL, Chen ZP et al (2007) Iodine nutrition status of population in the areas with different iodine concentrations of drinking water. Acta Nutr Sin 29:526–530 (in Chinese)
Metadaten
Titel
Impact of removing iodized salt on the iodine nutrition of children living in areas with variable iodine content in drinking water
verfasst von
Shengmin Lv
Yinglu Zhao
Yanxia Li
Yuchun Wang
Hua Liu
Yang Li
Jun Zhao
Shannon Rutherford
Publikationsdatum
01.09.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Nutrition / Ausgabe 6/2015
Print ISSN: 1436-6207
Elektronische ISSN: 1436-6215
DOI
https://doi.org/10.1007/s00394-014-0767-z

Weitere Artikel der Ausgabe 6/2015

European Journal of Nutrition 6/2015 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.