Clinical Research in Cardiology OnlineFirst articles

Open Access 25.03.2024 | Original Paper

Global longitudinal strain in long-term risk prediction after acute coronary syndrome: an investigation of added prognostic value to ejection fraction

Global longitudinal strain (GLS) by speckle tracking echocardiography is a sensitive marker of global systolic left ventricular (LV) function [ 1 ]. The bulk of literature in support of GLS as a predictor of adverse outcome in heart disease has …

verfasst von:: Joel Lenell, Bertil Lindahl, David Erlinge, Tomas Jernberg, Jonas Spaak, Tomasz Baron

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20.03.2024 | Original Paper

Short- and long-term outcomes of patients with active cancer presenting with an acute coronary syndrome

Improved survival among cancer patients in recent years resulted in larger numbers of patients having concomitant diagnoses of both cancer and cardiovascular disease (CVD). Moreover, patients with cancer are at increased risk for an acute coronary …

verfasst von:: Inbar Nardi Agmon, Ori Rahat, Roy Beigel, Tal Ovdat, Manhal Habib, Oran Tzuman, Limor Ilan Bushari, Ran Kornowski, Katia Orvin

Open Access 18.03.2024 | Editorial

Age- and sex-specific physiological cardiac remodeling: the search for the Fountain of Youth

verfasst von:: Philipp Markwirth, Bernhard Haring

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14.03.2024 | Original Paper

Lower revascularization rates after high-speed rotational atherectomy compared to modified balloons in calcified coronary lesions: 5-year outcomes of the randomized PREPARE-CALC trial

In contemporary percutaneous coronary intervention (PCI) practice, dealing with coronary artery calcification remains a challenge. The current PCI population includes predominantly older individuals with a higher incidence of comorbidities, making …

verfasst von:: Nader Mankerious, Gert Richardt, Abdelhakim Allali, Volker Geist, Adnan Kastrati, Mohamed El-Mawardy, Tobias Rheude, Dmitriy Sulimov, Ralph Toelg, Mohamed Abdel-Wahab

Open Access 13.03.2024 | Original Paper

Balloon technologies for pulmonary vein isolation—12-month outcome and comparison of the novel radiofrequency balloon with the cryoballoon in patients with paroxysmal atrial fibrillation

Pulmonary vein isolation (PVI), being more effective at maintaining sinus rhythm than medical therapy, has become the key therapy in the treatment of symptomatic AF [ 1 – 3 ].

verfasst von:: Jan-Hendrik van den Bruck, Jonas Wörmann, Arian Sultan, Karlo Filipovic, Katharina Seuthe, Susanne Erlhöfer, Cornelia Scheurlen, Sebastian Dittrich, Jan-Hendrik Schipper, Jakob Lüker, Daniel Steven

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13.03.2024 | Original Paper

Aortic regurgitation is associated with African American and Asian race, smoking, renal disease, and numerous autoimmune diseases in addition to traditional cardiovascular risk factors but has lower risk with alcohol intake

Aortic regurgitation (AR) also called aortic insufficiency has many underlying causes, including inflammation, age, and genetic disposition. The prevalence of AR has been estimated to be as high as 4.9%, with incidence and severity increasing with …

verfasst von:: Brandon Timmerman, Mehrtash Hashemzadeh, Mohammad Reza Movahed

11.03.2024 | Letter to the Editors

Systematic underestimation of myocardial perfusion reserve by regadenoson stress perfusion CMR—when haste makes waste

verfasst von:: Georgios Moutzoukis, Marie K. Lorenz, Thomas Schroeder, Benedict Schulte-Steinberg, Kelvin Chow, Peter Kellman, Raffi Bekeredjian, Nico Schmid, Heiko Mahrholdt, Andreas Seitz

Open Access 11.03.2024 | Original Paper

Sex-specific structural and functional cardiac remodeling during healthy aging assessed by cardiovascular magnetic resonance

The prevalence of cardiovascular diseases increases with rising age [ 1 , 2 ]. Global demographic change will likely impact not just patient’s health but also lead to an increasing burden on healthcare resources [ 2 ]. Therefore, research into the …

verfasst von:: Leonhard Grassow, Jan Gröschel, Hadil Saad, Leo Dyke Krüger, Johanna Kuhnt, Maximilian Müller, Thomas Hadler, Edyta Blaszczyk, Jeanette Schulz-Menger

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Open Access 11.03.2024 | Original Paper

Transcatheter aortic valve implantation in patients with significant septal hypertrophy

Transcatheter aortic valve implantation (TAVI) is a well-established therapy for severe aortic stenosis (AS) across all risk strata according to current guidelines for the management of valvular heart disease [ 1 , 2 ]. Multiple clinical risk …

verfasst von:: Martin Beyer, Till Joscha Demal, Oliver D. Bhadra, Matthias Linder, Sebastian Ludwig, David Grundmann, Lisa Voigtlaender-Buschmann, Lara Waldschmidt, Johannes Schirmer, Niklas Schofer, Simon Pecha, Stefan Blankenberg, Hermann Reichenspurner, Lenard Conradi, Moritz Seiffert, Andreas Schaefer

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Open Access 07.03.2024 | Original Paper

Ultra-long-term efficacy and safety of catheter-based renal denervation in resistant hypertension: 10-year follow-up outcomes

Despite the availability of various effective treatment modalities such as lifestyle modification and antihypertensive drugs, a significant proportion of patients remains above guideline-recommended blood pressure (BP) treatment targets [ 1 – 3 ].

verfasst von:: Hussam Al Ghorani, Saarraaken Kulenthiran, Lucas Lauder, Michael Johannes Maria Recktenwald, Juliane Dederer, Michael Kunz, Felix Götzinger, Sebastian Ewen, Christian Ukena, Michael Böhm, Felix Mahfoud

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07.03.2024 | Review

Effect of supervised exercise training on cardiovascular function in patients with intermittent claudication: a systematic review and meta-analysis of randomized controlled trials

This study aimed to determine the effect of supervised exercise training (SET) on cardiovascular function in patients with intermittent claudication (IC). A systematic search in MEDLINE, Embase, and Cochrane Central Register of Controlled Trials …

verfasst von:: Yu-Chen Xiao, Wan-Yang Li, Lei Zhang, Jie-Fu Fan, Wei-Zhong Wang, Yang-Kai Wang

Open Access 06.03.2024 | Original Paper

Deferral of non-emergency cardiac interventions is associated with increased emergency hospitalizations up to 24 months post-procedure

During the first phase of the COVID-19 crises in spring 2020, hospitals were forced to reduce their numbers of treatments to provide the capacity in anticipation of a demand surge for hospital beds from patients suffering from SARS-CoV-2 and to …

verfasst von:: Stefanie Andreß, Dominik Felbel, Dominik Buckert, Wolfgang Rottbauer, Armin Imhof, Tilman Stephan

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Open Access 06.03.2024 | Original Paper

Clinical value of a comprehensive clinical- and echocardiography-based risk score on predicting cardiovascular outcomes in ischemic heart failure patients with reduced ejection fraction

The prevalence of heart failure (HF) rises with the aging population and improved survival rates among patients with heart diseases due to modern treatment innovation [ 1 ]. Ischemic heart disease plays a significant role in contributing to HF and …

verfasst von:: Dan Liu, Kai Hu, Camilla Wagner, Björn Daniel Lengenfelder, Georg Ertl, Stefan Frantz, Peter Nordbeck

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06.03.2024 | Original Paper

Incidence and predictors of left atrial thrombus in patients with atrial fibrillation under anticoagulation therapy

Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice, and its incidence has significantly increased with the aging of the general population. Hemodynamic changes associated with AF, such as the loss of atrial …

verfasst von:: Joong Min Lee, Myung-Jin Cha, Gi-Byoung Nam, Kee-Joon Choi, Byung Joo Sun, Dae-Hee Kim, Jong-Min Song, Duk-Hyun Kang, Jae-Kwan Song, Min Soo Cho

06.03.2024 | Letter to the Editors

Unravelling gender differences in coronary artery disease: are we equal?

verfasst von:: Kyriakos Dimitriadis, Panayiotis Iliakis, Nikolaos Pyrpyris, Konstantinos Tsioufis

Open Access 06.03.2024 | Original Paper

Risk of death, thrombotic and hemorrhagic events in anticoagulated patients with atrial fibrillation and systemic autoimmune diseases: an analysis from a global federated dataset

Growing evidence shows that patients with systemic autoimmune diseases (SADs) have a high risk of incident atrial fibrillation (AF) [ 1 , 2 ]. Indeed, the dysregulated inflammatory response that characterizes SAD can contribute to the electrical …

verfasst von:: Tommaso Bucci, Chiara Cardamone, Massimo Triggiani, Paul R. J. Ames, Gregory Y. H. Lip

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Open Access 06.03.2024 | Original Paper

Role of preexisting right ventricular remodeling in symptoms and prognosis after transcatheter tricuspid valve repair

Tricuspid regurgitation (TR) is one of the most prevalent valvular diseases in the elderly population and significantly worsens clinical outcomes and survival in patients with heart failure [ 1 ]. With an aging population, the prevalence of TR is …

verfasst von:: Marc-André Ehrenfels, Caroline Fretter, Jennifer von Stein, Maria Isabel Körber, Hendrik Wienemann, Stephan Baldus, Roman Pfister, Christos Iliadis

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06.03.2024 | Letter to the Editors

Clinical benefit and limitations of CT imaging substrate visualization technology for VT ablation

verfasst von:: Naoya Kataoka, Teruhiko Imamura

Open Access 04.03.2024 | Original Paper

Non-femoral focused transaxillary access in TAVI: GARY data analysis and future trends

As transcatheter aortic valve implantation (TAVI) continues to expand to a broader and lower risk patient population and operator experiences increase constantly, the use of the transfemoral (TF) access is becoming even more dominant [ 1 , 2 ]. The …

verfasst von:: Max M. Meertens, Matti Adam, Andreas Beckmann, Stephan Ensminger, Christian Frerker, Moritz Seiffert, Jan-Malte Sinning, Raffi Bekeredjian, Thomas Walther, Friedhelm Beyersdorf, Helge Möllmann, Ümniye Balaban, Kaveh Eghbalzadeh, Tanja K. Rudolph, Sabine Bleiziffer

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Open Access 26.02.2024 | Original Paper

Prognostic implication of heart failure stage and left ventricular ejection fraction for patients with in-hospital cardiac arrest: a 16-year retrospective cohort study

An estimated 292,000 patients in the United States experience in-hospital cardiac arrest (IHCA) each year [ 1 ]. Approximately 18.8% of patients with IHCA survive to hospital discharge, and only about 12.9% of these patients have favorable …

verfasst von:: Chih-Hung Wang, Li-Ting Ho, Meng-Che Wu, Cheng-Yi Wu, Joyce Tay, Pei-I. Su, Min-Shan Tsai, Yen-Wen Wu, Wei-Tien Chang, Chien-Hua Huang, Wen-Jone Chen

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