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European Child & Adolescent Psychiatry

Erschienen in:

01.03.2010 | Review

Genetics of developmental dyslexia

verfasst von: Thomas S. Scerri, Gerd Schulte-Körne

Erschienen in: European Child & Adolescent Psychiatry | Ausgabe 3/2010

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Abstract

Developmental dyslexia is a highly heritable disorder with a prevalence of at least 5% in school-aged children. Linkage studies have identified numerous loci throughout the genome that are likely to harbour candidate dyslexia susceptibility genes. Association studies and the refinement of chromosomal translocation break points in individuals with dyslexia have resulted in the discovery of candidate genes at some of these loci. A key function of many of these genes is their involvement in neuronal migration. This complements anatomical abnormalities discovered in dyslexic brains, such as ectopias, that may be the result of irregular neuronal migration.

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Titel: Genetics of developmental dyslexia
verfasst von: Thomas S. Scerri
Gerd Schulte-Körne
Publikationsdatum: 01.03.2010
Verlag: Springer-Verlag
Erschienen in: European Child & Adolescent Psychiatry / Ausgabe 3/2010
Print ISSN: 1018-8827
Elektronische ISSN: 1435-165X
DOI: https://doi.org/10.1007/s00787-009-0081-0

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Genetics of developmental dyslexia

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