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01.05.2014 | Original article

Using fiducial markers in the prostate bed in postprostatectomy external beam radiation therapy improves accuracy over surgical clips

verfasst von: I. Fortin, MD, MSc, J.-F. Carrier, PhD, M.-C. Beauchemin, MD, D. Béliveau-Nadeau, MSc, G. Delouya, MD, D. Taussky, MD

Erschienen in: Strahlentherapie und Onkologie | Ausgabe 5/2014

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Abstract

Background and purpose

The purpose of this work was to assess the stability of fiducial markers in the prostate bed and compared their use to surgical clips.

Patients and methods

In this study, 3–4 gold fiducial markers were transrectally implanted in the prostate bed of 14 patients. The stability of the fiducial markers position (fiducial markers fixity) over an EBRT course was assessed. Furthermore, the advantages of the fiducial markers compared to the surgical clips were assessed and the interobserver variation between the two technologies was compared.

Results

The mean fiducial marker migration during a course of EBRT was small with 1.2 mm (SD ± 0.8 mm). Compared to fiducial markers, the matches with surgical clips were mismatched ≥ 2 mm in 68 % of treatments. This discrepancy of > 2 mm was on average 3.7 ± 1.3 mm. There was less interobserver variability for matching of fiducial markers (0.8 ± 0.7 mm) than for surgical clips (2.0 ± 1.6 mm).

Conclusion

Fiducial markers showed less interobserver variability in matching and less variation in position than surgical clips. Fiducial markers could ultimately help in reducing treatment margins.

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Titel: Using fiducial markers in the prostate bed in postprostatectomy external beam radiation therapy improves accuracy over surgical clips
verfasst von: I. Fortin, MD, MSc
J.-F. Carrier, PhD
M.-C. Beauchemin, MD
D. Béliveau-Nadeau, MSc
G. Delouya, MD
D. Taussky, MD
Publikationsdatum: 01.05.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: Strahlentherapie und Onkologie / Ausgabe 5/2014
Print ISSN: 0179-7158
Elektronische ISSN: 1439-099X
DOI: https://doi.org/10.1007/s00066-014-0631-3

Springer Medizin

Using fiducial markers in the prostate bed in postprostatectomy external beam radiation therapy improves accuracy over surgical clips