Erschienen in:
01.08.2006 | Review
Aspects of early arthritis. Definition of disease states in early arthritis: remission versus minimal disease activity
verfasst von:
Annette HM van der Helm-van Mil, Ferdinand C Breedveld, Tom WJ Huizinga
Erschienen in:
Arthritis Research & Therapy
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Ausgabe 4/2006
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Abstract
With regard to rheumatoid arthritis, remission as currently used in the literature can have two meanings: either a state with persistent absence of clinical and radiological signs of disease activity without being treated for a specific time period, or it may point to a disease state with minimal disease activity during antirheumatic treatment. A risk factor for the first is absence of autoantibodies, with the anti-CCP-antibodies as best predictors, whereas risk factors for achieving a drug-induced state of minimal disease activity are not well defined. These definitions of remission refer to different disease states; therefore, we propose that the term remission is reserved for patients that are not treated with antirheumatic drugs.