Skip to main content

Molecular Pain

Ausgabe 1/2008

Inhalt (67 Artikel)

Open Access Short report

Mutation I136V alters electrophysiological properties of the NaV1.7 channel in a family with onset of erythromelalgia in the second decade

Xiaoyang Cheng, Sulayman D Dib-Hajj, Lynda Tyrrell, Stephen G Waxman

Open Access Short report

The effect of deletion of the orphan G – protein coupled receptor (GPCR) gene MrgE on pain-like behaviours in mice

Peter J Cox, Tom Pitcher, Steven A Trim, Christine H Bell, Wenning Qin, Ross A Kinloch

Open Access Research

Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia

John K Neubert, Andrew J Mannes, Laszlo J Karai, Alan C Jenkins, Lanel Zawatski, Mones Abu-Asab, Michael J Iadarola

Open Access Editorial

Hit a new high

Min Zhuo, Jianguo Gu

Open Access Research

Expression of AMPA receptor subunits at synapses in laminae I–III of the rodent spinal dorsal horn

Erika Polgár, Masahiko Watanabe, Bettina Hartmann, Seth GN Grant, Andrew J Todd

Open Access Short report

Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain

Makoto Inoue, Lin Ma, Junken Aoki, Jerold Chun, Hiroshi Ueda

Open Access Research

Chronic morphine administration enhances nociceptive sensitivity and local cytokine production after incision

DeYong Liang, Xiaoyou Shi, Yanli Qiao, Martin S Angst, David C Yeomans, J David Clark

Open Access Research

Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis model

Hong Yang, Terry A McNearney, Rong Chu, Ying Lu, Yong Ren, David C Yeomans, Steven P Wilson, Karin N Westlund

Open Access Research

Influence of TRPV1 on diabetes-induced alterations in thermal pain sensitivity

Reddy M Pabbidi, Shuang-Quan Yu, Siying Peng, Romesh Khardori, Mary E Pauza, Louis S Premkumar

Open Access Research

Vascularization of the dorsal root ganglia and peripheral nerve of the mouse: Implications for chemical-induced peripheral sensory neuropathies

Juan M Jimenez-Andrade, Monica B Herrera, Joseph R Ghilardi, Marina Vardanyan, Ohannes K Melemedjian, Patrick W Mantyh

Open Access Methodology

A computational model for sex-specific genetic architecture of complex traits in humans: Implications for mapping pain sensitivity

Chenguang Wang, Yun Cheng, Tian Liu, Qin Li, Roger B Fillingim, Margaret R Wallace, Roland Staud, Lee Kaplan, Rongling Wu

Open Access Review

Molecular and cellular limits to somatosensory specificity

Carlos Belmonte, Félix Viana

Open Access Research

Selective activation of microglia in spinal cord but not higher cortical regions following nerve injury in adult mouse

Fuxing Zhang, Kujumon I Vadakkan, Susan S Kim, Long-Jun Wu, Yuze Shang, Min Zhuo

Open Access Research

Nav1.7 expression is increased in painful human dental pulp

Songjiang Luo, Griffin M Perry, S Rock Levinson, Michael A Henry

Open Access Research

Differential activation of p38 and extracellular signal-regulated kinase in spinal cord in a model of bee venom-induced inflammation and hyperalgesia

Xiu-Yu Cui, Yi Dai, Sheng-Lan Wang, Hiroki Yamanaka, Kimiko Kobayashi, Koichi Obata, Jun Chen, Koichi Noguchi

Open Access Research

Oxytocin-induced antinociception in the spinal cord is mediated by a subpopulation of glutamatergic neurons in lamina I-II which amplify GABAergic inhibition

Jean-Didier Breton, Pierre Veinante, Sandra Uhl-Bronner, Angela Maria Vergnano, Marie José Freund-Mercier, Rémy Schlichter, Pierrick Poisbeau

Open Access Short report

Compound heterozygosity in sodium channel Nav1.7 in a family with hereditary erythermalgia

Mark E Samuels, Rene HM te Morsche, Mary E Lynch, Joost PH Drenth

Open Access Research

TRPM8 mechanism of autonomic nerve response to cold in respiratory airway

Hong Xing, Jennifer X Ling, Meng Chen, Richard D Johnson, Makoto Tominaga, Cong-Yi Wang, Jianguo Gu

Open Access Research

Involvement of P311 in the affective, but not in the sensory component of pain

Yan-Gang Sun, Yong-Jing Gao, Zhong-Qiu Zhao, Bing Huang, Jun Yin, Gregory A Taylor, Zhou-Feng Chen

Open Access Short report

Hemispheric lateralization of a molecular signal for pain modulation in the amygdala

Yarimar Carrasquillo, Robert W Gereau IV

Open Access Research

PKA and ERK, but not PKC, in the amygdala contribute to pain-related synaptic plasticity and behavior

Yu Fu, Jeong Han, Titilope Ishola, Michelle Scerbo, Hita Adwanikar, Cara Ramsey, Volker Neugebauer

Open Access Research

Brain derived neurotrophic factor (BDNF) contributes to the pain hypersensitivity following surgical incision in the rats

Chang-Qi Li, Jun-Mei Xu, Dan Liu, Jian-Yi Zhang, Ru-Ping Dai

Open Access Review

Histamine-induced itch and its relationship with pain

Won-Sik Shim, Uhtaek Oh

Open Access Research

Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1

Lillian Cruz-Orengo, Ajay Dhaka, Robert J Heuermann, Timothy J Young, Michael C Montana, Eric J Cavanaugh, Donghee Kim, Gina M Story

Open Access Research

Modulation of chloride homeostasis by inflammatory mediators in dorsal root ganglion neurons

Katharina Funk, Anne Woitecki, Christina Franjic-Würtz, Thomas Gensch, Frank Möhrlen, Stephan Frings

Open Access Research

Proteomic profiling of neuromas reveals alterations in protein composition and local protein synthesis in hyper-excitable nerves

Hong-Lei Huang, Cruz-Miguel Cendan, Carolina Roza, Kenji Okuse, Rainer Cramer, John F Timms, John N Wood

Open Access Research

Anticipation of pain enhances the nociceptive transmission and functional connectivity within pain network in rats

Jin-Yan Wang, Han-Ti Zhang, Jing-Yu Chang, Donald J Woodward, Luiz A Baccalá, Fei Luo

Open Access Research

The role of cation-dependent chloride transporters in neuropathic pain following spinal cord injury

Samuel W Cramer, Christopher Baggott, John Cain, Jessica Tilghman, Bradley Allcock, Gurwattan Miranpuri, Sharad Rajpal, Dandan Sun, Daniel Resnick

Open Access Research

Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable

Sulayman D Dib-Hajj, Mark Estacion, Brian W Jarecki, Lynda Tyrrell, Tanya Z Fischer, Mark Lawden, Theodore R Cummins, Stephen G Waxman

Open Access Research

The chemokine CXCL1/growth related oncogene increases sodium currents and neuronal excitability in small diameter sensory neurons

Jun-Gang Wang, Judith A Strong, Wenrui Xie, Rui-Hua Yang, Dennis E Coyle, Dayna M Wick, Ericka D Dorsey, Jun-Ming Zhang

Open Access Research

Enhancement of presynaptic glutamate release and persistent inflammatory pain by increasing neuronal cAMP in the anterior cingulate cortex

Long-Jun Wu, Hendrik W Steenland, Susan S Kim, Carolina Isiegas, Ted Abel, Bong-Kiun Kaang, Min Zhuo

Open Access Research

Differential regulation of morphine antinociceptive effects by endogenous enkephalinergic system in the forebrain of mice

Tsung-Chieh Chen, Ying-Ying Cheng, Wei-Zen Sun, Bai-Chuang Shyu

Open Access Research

Direct activation of Transient Receptor Potential Vanilloid 1(TRPV1) by Diacylglycerol (DAG)

Dong Ho Woo, Sung Jun Jung, Mei Hong Zhu, Chul-Kyu Park, Yong Ho Kim, Seog Bae Oh, C Justin Lee

Open Access Research

Characterization of mouse orofacial pain and the effects of lesioning TRPV1-expressing neurons on operant behavior

John K Neubert, Christopher King, Wendi Malphurs, Fong Wong, James P Weaver, Alan C Jenkins, Heather L Rossi, Robert M Caudle

Open Access Research

A preliminary fMRI study of analgesic treatment in chronic back pain and knee osteoarthritis

Marwan N Baliki, Paul Y Geha, Rami Jabakhanji, Norm Harden, Thomas J Schnitzer, A Vania Apkarian

Open Access Research

HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity

Samer R Eid, Eric D Crown, Eric L Moore, Hongyu A Liang, Kar-Chan Choong, Shelley Dima, Darrell A Henze, Stefanie A Kane, Mark O Urban

Open Access Research

Cutaneous tactile allodynia associated with microvascular dysfunction in muscle

Andre Laferrière, Magali Millecamps, Dimitris N Xanthos, Wen Hua Xiao, Chiang Siau, Marissa de Mos, Christelle Sachot, J Vaigunda Ragavendran, Frank JPM Huygen, Gary J Bennett, Terence J Coderre

Open Access Review

Effects of general anesthetics on visceral pain transmission in the spinal cord

Yun Wang, Jing Wu, Qing Lin, HJ Nauta, Yun Yue, Li Fang

Open Access Research

Quantitative Real-Time PCR detection of TRPV1–4 gene expression in human leukocytes from healthy and hyposensitive subjects

Giacomo Spinsanti, Raffaella Zannolli, Cristina Panti, Ilaria Ceccarelli, Letizia Marsili, Valeria Bachiocco, Francesco Frati, Anna Maria Aloisi

Open Access Short report

Prolonged gabapentin analgesia in an experimental mouse model of fibromyalgia

Michiko Nishiyori, Hiroshi Ueda

Open Access Research

Sumatriptan inhibits synaptic transmission in the rat midbrain periaqueductal grey

Hyo-Jin Jeong, David Chenu, Emma E Johnson, Mark Connor, Christopher W Vaughan

Open Access Research

FMRI connectivity analysis of acupuncture effects on an amygdala-associated brain network

Wei Qin, Jie Tian, Lijun Bai, Xiaohong Pan, Lin Yang, Peng Chen, Jianping Dai, Lin Ai, Baixiao Zhao, Qiyong Gong, Wei Wang, Karen M von Deneen, Yijun Liu

Open Access Short report

Autonomic fiber sprouting in the skin in chronic inflammation

Lina Almarestani, Geraldine Longo, Alfredo Ribeiro-da-Silva

Open Access Research

Single dose of morphine produced a prolonged effect on dopamine neuron activities

Die Zhang, Hai Zhang, Guo-zhang Jin, Kehong Zhang, Xuechu Zhen

Open Access Research

Does the pain-protective GTP cyclohydrolase haplotype significantly alter the pattern or severity of pain in humans with chronic pancreatitis?

Mark Lazarev, Janette Lamb, M Michael Barmada, Feng Dai, Michelle A Anderson, Mitchell B Max, David C Whitcomb

Open Access Research

Mechanisms involved in an increment of multimodal excitability of medullary and upper cervical dorsal horn neurons following cutaneous capsaicin treatment

Kuniya Honda, Junichi Kitagawa, Barry J Sessle, Masahiro Kondo, Yoshiyuki Tsuboi, Yoshiyuki Yonehara, Koichi Iwata

Open Access Research

Targeted mutation of EphB1 receptor prevents development of neuropathic hyperalgesia and physical dependence on morphine in mice

Yuan Han, Xue-Song Song, Wen-Tao Liu, Mark Henkemeyer, Xue-Jun Song

Open Access Research

Origins, actions and dynamic expression patterns of the neuropeptide VGF in rat peripheral and central sensory neurones following peripheral nerve injury

Andrew Moss, Rachel Ingram, Stephanie Koch, Andria Theodorou, Lucie Low, Mark Baccei, Gareth J Hathway, Michael Costigan, Stephen R Salton, Maria Fitzgerald

Open Access Research

Long-term actions of interleukin-1β on delay and tonic firing neurons in rat superficial dorsal horn and their relevance to central sensitization

Sabrina L Gustafson-Vickers, Van B Lu, Aaron Y Lai, Kathryn G Todd, Klaus Ballanyi, Peter A Smith

Open Access Research

Genetic variation in the Catechol-O-Methyltransferase (COMT) gene and morphine requirements in cancer patients with pain

Trude T Rakvåg, Joy R Ross, Hiroe Sato, Frank Skorpen, Stein Kaasa, Pål Klepstad

Open Access Research

Gene transfer of GLT-1, a glial glutamate transporter, into the spinal cord by recombinant adenovirus attenuates inflammatory and neuropathic pain in rats

Sanae Maeda, Ai Kawamoto, Yumi Yatani, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kaneko

Open Access Research

Altered ATP release and metabolism in dorsal root ganglia of neuropathic rats

Yoshizo Matsuka, Takeshi Ono, Hirotate Iwase, Somsak Mitrirattanakul, Kevin S Omoto, Ting Cho, Yan Yan N Lam, Bradley Snyder, Igor Spigelman

Open Access Research

Role of spinal cord alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in complete Freund's adjuvant-induced inflammatory pain

Jang-Su Park, Myron Yaster, Xiaowei Guan, Ji-Tian Xu, Ming-Hung Shih, Yun Guan, Srinivasa N Raja, Yuan-Xiang Tao

Mehr Frauen im OP – weniger postoperative Komplikationen

21.05.2024 Allgemeine Chirurgie Nachrichten

Ein Frauenanteil von mindestens einem Drittel im ärztlichen Op.-Team war in einer großen retrospektiven Studie aus Kanada mit einer signifikanten Reduktion der postoperativen Morbidität assoziiert.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

Delir bei kritisch Kranken – Antipsychotika versus Placebo

16.05.2024 Delir Nachrichten

Um die Langzeitfolgen eines Delirs bei kritisch Kranken zu mildern, wird vielerorts auf eine Akuttherapie mit Antipsychotika gesetzt. Eine US-amerikanische Forschungsgruppe äußert jetzt erhebliche Vorbehalte gegen dieses Vorgehen. Denn es gibt neue Daten zum Langzeiteffekt von Haloperidol bzw. Ziprasidon versus Placebo.

Klinikreform soll zehntausende Menschenleben retten

15.05.2024 Klinik aktuell Nachrichten

Gesundheitsminister Lauterbach hat die vom Bundeskabinett beschlossene Klinikreform verteidigt. Kritik an den Plänen kommt vom Marburger Bund. Und in den Ländern wird über den Gang zum Vermittlungsausschuss spekuliert.

Update AINS

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.