Skip to main content
Erschienen in: Die Orthopädie 3/2023

28.02.2023 | Leitthema

Noninfectious tissue interactions at periprosthetic interfaces

verfasst von: Dr. Frank Schulze, Giorgio Perino, MD, Anastasia Rakow, MD, Prof. Dr. Georgi Wassilew, Dr. Janosch Schoon

Erschienen in: Die Orthopädie | Ausgabe 3/2023

Einloggen, um Zugang zu erhalten

Abstract

The success of hip arthroplasty is based on modern materials in addition to the continuous development of surgical techniques and clinical experience gained over six decades. The biocompatible implant materials used in hip arthroplasty can be textured or coated with biomimetic surfaces to ensure durable component ingrowth and moderate host response. Material integrity plays a critical role in the durability of the stable interface between implant components and periprosthetic tissues. Inflammation at the interfaces due to the release of degradation products from the implant materials is one of the causes of hip arthroplasty failure. This review summarizes the implant materials currently used in hip arthroplasty, their preclinical testing and the postoperative neogenesis of periprosthetic tissues, and the interactions of periprosthetic bone and the implant materials at the periprosthetic interfaces.
Literatur
1.
Zurück zum Zitat Čolić K, Grbović A, Sedmak A, Legweel K (2018) Application of numerical methods in design and analysis of orthopedic implant integrity. In: Experimental and numerical investigations in materials science and engineering. Springer, Cham, pp 96–111 Čolić K, Grbović A, Sedmak A, Legweel K (2018) Application of numerical methods in design and analysis of orthopedic implant integrity. In: Experimental and numerical investigations in materials science and engineering. Springer, Cham, pp 96–111
2.
Zurück zum Zitat Bistolfi A, Giustra F, Bosco F, Sabatini L, Aprato A, Bracco P, Bellare A (2021) Ultra-high molecular weight polyethylene (UHMWPE) for hip and knee arthroplasty: The present and the future. J Orthop 25:98–106PubMedPubMedCentralCrossRef Bistolfi A, Giustra F, Bosco F, Sabatini L, Aprato A, Bracco P, Bellare A (2021) Ultra-high molecular weight polyethylene (UHMWPE) for hip and knee arthroplasty: The present and the future. J Orthop 25:98–106PubMedPubMedCentralCrossRef
3.
Zurück zum Zitat Naghavi SA, Lin C, Sun C, Tamaddon M, Basiouny M, Garcia-Souto P, Taylor S, Hua J, Li D, Wang L (2022) Stress shielding and bone resorption of press-fit polyether–ether–ketone (PEEK) hip prosthesis: a sawbone model study. Polymers 14(21):4600PubMedPubMedCentralCrossRef Naghavi SA, Lin C, Sun C, Tamaddon M, Basiouny M, Garcia-Souto P, Taylor S, Hua J, Li D, Wang L (2022) Stress shielding and bone resorption of press-fit polyether–ether–ketone (PEEK) hip prosthesis: a sawbone model study. Polymers 14(21):4600PubMedPubMedCentralCrossRef
4.
Zurück zum Zitat Belwanshi M, Jayaswal P, Aherwar A (2022) Mechanical behaviour investigation of PEEK coated titanium alloys for hip arthroplasty using finite element analysis. Mater Today Proc 56:2808–2817CrossRef Belwanshi M, Jayaswal P, Aherwar A (2022) Mechanical behaviour investigation of PEEK coated titanium alloys for hip arthroplasty using finite element analysis. Mater Today Proc 56:2808–2817CrossRef
5.
Zurück zum Zitat Koh Y‑G, Park K‑M, Lee J‑A, Nam J‑H, Lee H‑Y, Kang K‑T (2019) Total knee arthroplasty application of polyetheretherketone and carbon-fiber-reinforced polyetheretherketone: A review. Mater Sci Eng C Mater Biol Appl 100:70–81PubMedCrossRef Koh Y‑G, Park K‑M, Lee J‑A, Nam J‑H, Lee H‑Y, Kang K‑T (2019) Total knee arthroplasty application of polyetheretherketone and carbon-fiber-reinforced polyetheretherketone: A review. Mater Sci Eng C Mater Biol Appl 100:70–81PubMedCrossRef
6.
Zurück zum Zitat Brockett CL, Carbone S, Fisher J, Jennings LM (2017) PEEK and CFR-PEEK as alternative bearing materials to UHMWPE in a fixed bearing total knee replacement: an experimental wear study. Wear 374:86–91PubMedCrossRef Brockett CL, Carbone S, Fisher J, Jennings LM (2017) PEEK and CFR-PEEK as alternative bearing materials to UHMWPE in a fixed bearing total knee replacement: an experimental wear study. Wear 374:86–91PubMedCrossRef
8.
Zurück zum Zitat Ihaddadene R, Affatato S, Zavalloni M, Bouzid S, Viceconti M (2011) Carbon composition effects on wear behaviour and wear mechanisms of metal-on-metal hip prosthesis. Comput Methods Biomech Biomed Engin 14(S1):33–34CrossRef Ihaddadene R, Affatato S, Zavalloni M, Bouzid S, Viceconti M (2011) Carbon composition effects on wear behaviour and wear mechanisms of metal-on-metal hip prosthesis. Comput Methods Biomech Biomed Engin 14(S1):33–34CrossRef
9.
Zurück zum Zitat Keegan GM, Learmonth ID, Case C (2008) A systematic comparison of the actual, potential, and theoretical health effects of cobalt and chromium exposures from industry and surgical implants. Crit Rev Toxicol 38(8):645–674PubMedCrossRef Keegan GM, Learmonth ID, Case C (2008) A systematic comparison of the actual, potential, and theoretical health effects of cobalt and chromium exposures from industry and surgical implants. Crit Rev Toxicol 38(8):645–674PubMedCrossRef
10.
Zurück zum Zitat Ghosh S, Abanteriba S, Wong S, Houshyar S (2018) Selective laser melted titanium alloys for hip implant applications: Surface modification with new method of polymer grafting. J Mech Behav Biomed Mater 87:312–324PubMedCrossRef Ghosh S, Abanteriba S, Wong S, Houshyar S (2018) Selective laser melted titanium alloys for hip implant applications: Surface modification with new method of polymer grafting. J Mech Behav Biomed Mater 87:312–324PubMedCrossRef
11.
Zurück zum Zitat Tang J, Luo J, Huang Y, Sun J, Zhu Z, Xu J, Dargusch M, Yan M (2020) Immunological response triggered by metallic 3D printing powders. Addit Manuf 35:101392 Tang J, Luo J, Huang Y, Sun J, Zhu Z, Xu J, Dargusch M, Yan M (2020) Immunological response triggered by metallic 3D printing powders. Addit Manuf 35:101392
12.
Zurück zum Zitat Kong K, Zhao C, Chang Y, Qiao H, Hu Y, Li H, Zhang J (2022) Use of customized 3D-printed titanium augment with tantalum trabecular cup for large acetabular bone defects in revision total hip arthroplasty: A midterm follow-up study. Front Bioeng Biotechnol. https://doi.org/10.3389/fbioe.2022.900905 Kong K, Zhao C, Chang Y, Qiao H, Hu Y, Li H, Zhang J (2022) Use of customized 3D-printed titanium augment with tantalum trabecular cup for large acetabular bone defects in revision total hip arthroplasty: A midterm follow-up study. Front Bioeng Biotechnol. https://​doi.​org/​10.​3389/​fbioe.​2022.​900905
13.
Zurück zum Zitat Kurtz SM, Kocagöz S, Arnholt C, Huet R, Ueno M, Walter WL (2014) Advances in zirconia toughened alumina biomaterials for total joint replacement. J Mech Behav Biomed Mater 31:107–116PubMedCrossRef Kurtz SM, Kocagöz S, Arnholt C, Huet R, Ueno M, Walter WL (2014) Advances in zirconia toughened alumina biomaterials for total joint replacement. J Mech Behav Biomed Mater 31:107–116PubMedCrossRef
14.
Zurück zum Zitat Carli AV, Patel AR, Cross MB, Mayman DJ, Carroll KM, Pellicci PM, Jerabek SA (2020) Long-term performance of oxidized zirconium on conventional and highly cross-linked polyethylene in total hip arthroplasty. SICOT J 6:10PubMedPubMedCentralCrossRef Carli AV, Patel AR, Cross MB, Mayman DJ, Carroll KM, Pellicci PM, Jerabek SA (2020) Long-term performance of oxidized zirconium on conventional and highly cross-linked polyethylene in total hip arthroplasty. SICOT J 6:10PubMedPubMedCentralCrossRef
15.
Zurück zum Zitat Sabokbar A, Athanasou NA, Murray DW (2001) Osteolysis induced by radio-opaque agents, bone cements and cementing technique. Springer, Berlin, Heidelberg, pp 149–161CrossRef Sabokbar A, Athanasou NA, Murray DW (2001) Osteolysis induced by radio-opaque agents, bone cements and cementing technique. Springer, Berlin, Heidelberg, pp 149–161CrossRef
16.
Zurück zum Zitat Cooper HJ, Ranawat AS, Potter HG, Foo LF, Jawetz ST, Ranawat CS (2009) Magnetic resonance imaging in the diagnosis and management of hip pain after total hip arthroplasty. J Arthroplasty 24(5):661–667PubMedCrossRef Cooper HJ, Ranawat AS, Potter HG, Foo LF, Jawetz ST, Ranawat CS (2009) Magnetic resonance imaging in the diagnosis and management of hip pain after total hip arthroplasty. J Arthroplasty 24(5):661–667PubMedCrossRef
17.
Zurück zum Zitat Monopoli MP, Åberg C, Salvati A, Dawson KA (2012) Biomolecular coronas provide the biological identity of nanosized materials. Nat Nanotechnol 7(12):779–786PubMedCrossRef Monopoli MP, Åberg C, Salvati A, Dawson KA (2012) Biomolecular coronas provide the biological identity of nanosized materials. Nat Nanotechnol 7(12):779–786PubMedCrossRef
18.
Zurück zum Zitat Perino G, De Martino I, Zhang L, Xia Z, Gallo J, Natu S, Langton D, Huber M, Rakow A, Schoon J (2021) The contribution of the histopathological examination to the diagnosis of adverse local tissue reactions in arthroplasty. EFORT Open Rev 6(6):399–419PubMedPubMedCentralCrossRef Perino G, De Martino I, Zhang L, Xia Z, Gallo J, Natu S, Langton D, Huber M, Rakow A, Schoon J (2021) The contribution of the histopathological examination to the diagnosis of adverse local tissue reactions in arthroplasty. EFORT Open Rev 6(6):399–419PubMedPubMedCentralCrossRef
19.
Zurück zum Zitat Xia Z, Ricciardi BF, Liu Z, von Ruhland C, Ward M, Lord A, Hughes L, Goldring SR, Purdue E, Murray D (2017) Nano-analyses of wear particles from metal-on-metal and non-metal-on-metal dual modular neck hip arthroplasty. Nanomed Nanotechnol Biol Med 13(3):1205–1217CrossRef Xia Z, Ricciardi BF, Liu Z, von Ruhland C, Ward M, Lord A, Hughes L, Goldring SR, Purdue E, Murray D (2017) Nano-analyses of wear particles from metal-on-metal and non-metal-on-metal dual modular neck hip arthroplasty. Nanomed Nanotechnol Biol Med 13(3):1205–1217CrossRef
20.
Zurück zum Zitat Johanson NA, Bullough PG, JR Wilson PD, Salvati EA, Ranawat CS (1987) The microscopic anatomy of the bone-cement interface in failed total hip arthroplasties. Clin Orthop Relat Res 218:123–135CrossRef Johanson NA, Bullough PG, JR Wilson PD, Salvati EA, Ranawat CS (1987) The microscopic anatomy of the bone-cement interface in failed total hip arthroplasties. Clin Orthop Relat Res 218:123–135CrossRef
21.
Zurück zum Zitat Xue T, Attarilar S, Liu S, Liu J, Song X, Li L, Zhao B, Tang Y (2020) Surface modification techniques of titanium and its alloys to functionally optimize their biomedical properties: thematic review. Front Bioeng Biotechnol 8:603072PubMedPubMedCentralCrossRef Xue T, Attarilar S, Liu S, Liu J, Song X, Li L, Zhao B, Tang Y (2020) Surface modification techniques of titanium and its alloys to functionally optimize their biomedical properties: thematic review. Front Bioeng Biotechnol 8:603072PubMedPubMedCentralCrossRef
22.
Zurück zum Zitat Van Der Straeten C, Calistri A, Grammatopoulos G, De Smet K (2020) Radiographic evaluation of hip resurfacing: the role of x‑rays in the diagnosis of a problematic resurfaced hip. HIP Int 30(2):167–175PubMedCrossRef Van Der Straeten C, Calistri A, Grammatopoulos G, De Smet K (2020) Radiographic evaluation of hip resurfacing: the role of x‑rays in the diagnosis of a problematic resurfaced hip. HIP Int 30(2):167–175PubMedCrossRef
23.
Zurück zum Zitat Krenn V, Perino G (2017) Histological diagnosis of implant-associated pathologies, Histological diagnosis of implant-associated pathologies. Springer, Berlin, Heidelberg, pp 1–44 Krenn V, Perino G (2017) Histological diagnosis of implant-associated pathologies, Histological diagnosis of implant-associated pathologies. Springer, Berlin, Heidelberg, pp 1–44
24.
Zurück zum Zitat Salib CG, Lewallen EA, Paradise CR, Tibbo ME, Robin JX, Trousdale WH, Morrey LM, Xiao J, Turner TW, Limberg AK (2019) Molecular pathology of adverse local tissue reaction caused by metal-on-metal implants defined by RNA-seq. Genomics 111(6):1404–1411PubMedCrossRef Salib CG, Lewallen EA, Paradise CR, Tibbo ME, Robin JX, Trousdale WH, Morrey LM, Xiao J, Turner TW, Limberg AK (2019) Molecular pathology of adverse local tissue reaction caused by metal-on-metal implants defined by RNA-seq. Genomics 111(6):1404–1411PubMedCrossRef
25.
Zurück zum Zitat Vaculova J, Gallo J, Hurnik P, Motyka O, Goodman SB, Dvorackova J (2018) Low intrapatient variability of histomorphological findings in periprosthetic tissues from revised metal/ceramic on polyethylene joint arthroplasties. J Biomed Mater Res 106(5):2008–2018CrossRef Vaculova J, Gallo J, Hurnik P, Motyka O, Goodman SB, Dvorackova J (2018) Low intrapatient variability of histomorphological findings in periprosthetic tissues from revised metal/ceramic on polyethylene joint arthroplasties. J Biomed Mater Res 106(5):2008–2018CrossRef
26.
Zurück zum Zitat Nich C, Takakubo Y, Pajarinen J, Ainola M, Salem A, Sillat T, Rao AJ, Raska M, Tamaki Y, Takagi M (2013) Macrophages—Key cells in the response to wear debris from joint replacements. J Biomed Mater Res A 101(10):3033–3045PubMedPubMedCentralCrossRef Nich C, Takakubo Y, Pajarinen J, Ainola M, Salem A, Sillat T, Rao AJ, Raska M, Tamaki Y, Takagi M (2013) Macrophages—Key cells in the response to wear debris from joint replacements. J Biomed Mater Res A 101(10):3033–3045PubMedPubMedCentralCrossRef
27.
28.
Zurück zum Zitat Behzadi S, Serpooshan V, Tao W, Hamaly MA, Alkawareek MY, Dreaden EC, Brown D, Alkilany AM, Farokhzad OC, Mahmoudi M (2017) Cellular uptake of nanoparticles: journey inside the cell. Chem Soc Rev 46(14):4218–4244PubMedPubMedCentralCrossRef Behzadi S, Serpooshan V, Tao W, Hamaly MA, Alkawareek MY, Dreaden EC, Brown D, Alkilany AM, Farokhzad OC, Mahmoudi M (2017) Cellular uptake of nanoparticles: journey inside the cell. Chem Soc Rev 46(14):4218–4244PubMedPubMedCentralCrossRef
29.
Zurück zum Zitat Kumari S, Mg S, Mayor S (2010) Endocytosis unplugged: multiple ways to enter the cell. Cell Res 20(3):256–275PubMedCrossRef Kumari S, Mg S, Mayor S (2010) Endocytosis unplugged: multiple ways to enter the cell. Cell Res 20(3):256–275PubMedCrossRef
30.
Zurück zum Zitat Scharf B, Clement CC, Zolla V, Perino G, Yan B, Elci SG, Purdue E, Goldring S, Macaluso F, Cobelli N (2014) Molecular analysis of chromium and cobalt-related toxicity. Sci Rep 4(1):1–12CrossRef Scharf B, Clement CC, Zolla V, Perino G, Yan B, Elci SG, Purdue E, Goldring S, Macaluso F, Cobelli N (2014) Molecular analysis of chromium and cobalt-related toxicity. Sci Rep 4(1):1–12CrossRef
31.
Zurück zum Zitat Xu H, Guo C, Gao Z, Wang C, Zhang H, Lv C, Yin Z, Wang Y (2018) Micrometer-sized titanium particles induce aseptic loosening in rabbit knee. Biomed Res Int 2018:1–11 Xu H, Guo C, Gao Z, Wang C, Zhang H, Lv C, Yin Z, Wang Y (2018) Micrometer-sized titanium particles induce aseptic loosening in rabbit knee. Biomed Res Int 2018:1–11
32.
Zurück zum Zitat Hall DJ, Pourzal R, Jacobs JJ, Urban RM (2019) Metal wear particles in hematopoietic marrow of the axial skeleton in patients with prior revision for mechanical failure of a hip or knee arthroplasty. J Biomed Mater Res B Appl Biomater 107(6):1930–1936PubMedCrossRef Hall DJ, Pourzal R, Jacobs JJ, Urban RM (2019) Metal wear particles in hematopoietic marrow of the axial skeleton in patients with prior revision for mechanical failure of a hip or knee arthroplasty. J Biomed Mater Res B Appl Biomater 107(6):1930–1936PubMedCrossRef
33.
Zurück zum Zitat Jain N, Moeller J, Vogel V (2019) Mechanobiology of macrophages: how physical factors coregulate macrophage plasticity and phagocytosis. Annu Rev Biomed Eng 21:267–297PubMedCrossRef Jain N, Moeller J, Vogel V (2019) Mechanobiology of macrophages: how physical factors coregulate macrophage plasticity and phagocytosis. Annu Rev Biomed Eng 21:267–297PubMedCrossRef
34.
Zurück zum Zitat Matthies AK, Skinner JA, Osmani H, Henckel J, Hart AJ (2012) Pseudotumors are common in well-positioned low-wearing metal-on-metal hips. Clin Orthop Relat Res 470(7):1895–1906PubMedCrossRef Matthies AK, Skinner JA, Osmani H, Henckel J, Hart AJ (2012) Pseudotumors are common in well-positioned low-wearing metal-on-metal hips. Clin Orthop Relat Res 470(7):1895–1906PubMedCrossRef
35.
Zurück zum Zitat Van Goethem E, Poincloux R, Gauffre F, Maridonneau-Parini I, Le Cabec V (2010) Matrix architecture dictates three-dimensional migration modes of human macrophages: differential involvement of proteases and podosome-like structures. J Immunol 184(2):1049–1061PubMedCrossRef Van Goethem E, Poincloux R, Gauffre F, Maridonneau-Parini I, Le Cabec V (2010) Matrix architecture dictates three-dimensional migration modes of human macrophages: differential involvement of proteases and podosome-like structures. J Immunol 184(2):1049–1061PubMedCrossRef
36.
Zurück zum Zitat Galluzzi L, Kepp O, Chan FK‑M, Kroemer G (2017) Necroptosis: mechanisms and relevance to disease. Annu Rev Pathol 12:103PubMedCrossRef Galluzzi L, Kepp O, Chan FK‑M, Kroemer G (2017) Necroptosis: mechanisms and relevance to disease. Annu Rev Pathol 12:103PubMedCrossRef
37.
Zurück zum Zitat Huber M, Reinisch G, Zenz P, Zweymüller K, Lintner F (2010) Postmortem study of femoral osteolysis associated with metal-on-metal articulation in total hip replacement: an analysis of nine cases. JBJS 92(8):1720–1731CrossRef Huber M, Reinisch G, Zenz P, Zweymüller K, Lintner F (2010) Postmortem study of femoral osteolysis associated with metal-on-metal articulation in total hip replacement: an analysis of nine cases. JBJS 92(8):1720–1731CrossRef
38.
Zurück zum Zitat Jiang H, Wang Y, Deng Z, Jin J, Meng J, Chen S, Wang J, Qiu Y, Guo T, Zhao J (2018) Construction and evaluation of a murine calvarial osteolysis model by exposure to cocrmo particles in aseptic loosening. J Vis Exp 13(2):e56276 Jiang H, Wang Y, Deng Z, Jin J, Meng J, Chen S, Wang J, Qiu Y, Guo T, Zhao J (2018) Construction and evaluation of a murine calvarial osteolysis model by exposure to cocrmo particles in aseptic loosening. J Vis Exp 13(2):e56276
39.
Zurück zum Zitat Koreny T, Tunyogi-Csapó M, Gál I, Vermes C, Jacobs JJ, Glant TT (2006) The role of fibroblasts and fibroblast-derived factors in periprosthetic osteolysis. Arthritis Rheum 54(10):3221–3232PubMedCrossRef Koreny T, Tunyogi-Csapó M, Gál I, Vermes C, Jacobs JJ, Glant TT (2006) The role of fibroblasts and fibroblast-derived factors in periprosthetic osteolysis. Arthritis Rheum 54(10):3221–3232PubMedCrossRef
41.
Zurück zum Zitat Takemoto M, Fujibayashi S, Neo M, Suzuki J, Kokubo T, Nakamura T (2005) Mechanical properties and osteoconductivity of porous bioactive titanium. Biomaterials 26(30):6014–6023PubMedCrossRef Takemoto M, Fujibayashi S, Neo M, Suzuki J, Kokubo T, Nakamura T (2005) Mechanical properties and osteoconductivity of porous bioactive titanium. Biomaterials 26(30):6014–6023PubMedCrossRef
42.
Zurück zum Zitat Lakstein D, Kopelovitch W, Barkay Z, Bahaa M, Hendel D, Eliaz N (2009) Enhanced osseointegration of grit-blasted, NaOH-treated and electrochemically hydroxyapatite-coated Ti–6Al–4V implants in rabbits. Acta Biomater 5(6):2258–2269PubMedCrossRef Lakstein D, Kopelovitch W, Barkay Z, Bahaa M, Hendel D, Eliaz N (2009) Enhanced osseointegration of grit-blasted, NaOH-treated and electrochemically hydroxyapatite-coated Ti–6Al–4V implants in rabbits. Acta Biomater 5(6):2258–2269PubMedCrossRef
43.
Zurück zum Zitat Huang G, Pan S‑T, Qiu J‑X (2021) The clinical application of porous tantalum and its new development for bone tissue engineering. Materials 14(10):2647PubMedPubMedCentralCrossRef Huang G, Pan S‑T, Qiu J‑X (2021) The clinical application of porous tantalum and its new development for bone tissue engineering. Materials 14(10):2647PubMedPubMedCentralCrossRef
44.
Zurück zum Zitat Kohli N, Stoddart JC, van Arkel RJ (2021) The limit of tolerable micromotion for implant osseointegration: a systematic review. Sci Rep 11(1):1–11CrossRef Kohli N, Stoddart JC, van Arkel RJ (2021) The limit of tolerable micromotion for implant osseointegration: a systematic review. Sci Rep 11(1):1–11CrossRef
45.
Zurück zum Zitat Rakow A, Schoon J, Dienelt A, John T, Textor M, Duda G, Perka C, Schulze F, Ode A (2016) Influence of particulate and dissociated metal-on-metal hip endoprosthesis wear on mesenchymal stromal cells in vivo and in vitro. Biomaterials 98:31–40PubMedCrossRef Rakow A, Schoon J, Dienelt A, John T, Textor M, Duda G, Perka C, Schulze F, Ode A (2016) Influence of particulate and dissociated metal-on-metal hip endoprosthesis wear on mesenchymal stromal cells in vivo and in vitro. Biomaterials 98:31–40PubMedCrossRef
46.
Zurück zum Zitat Schoon J, Hesse B, Tucoulou R, Geissler S, Ort M, Duda GN, Perka C, Wassilew GI, Perino G, Rakow A (2022) Synchrotron-based characterization of arthroprosthetic CoCrMo particles in human bone marrow. J Mater Sci Mater Med 33(6):54PubMedPubMedCentralCrossRef Schoon J, Hesse B, Tucoulou R, Geissler S, Ort M, Duda GN, Perka C, Wassilew GI, Perino G, Rakow A (2022) Synchrotron-based characterization of arthroprosthetic CoCrMo particles in human bone marrow. J Mater Sci Mater Med 33(6):54PubMedPubMedCentralCrossRef
47.
Zurück zum Zitat Schoon J, Hesse B, Rakow A, Ort MJ, Lagrange A, Jacobi D, Winter A, Huesker K, Reinke S, Cotte M, Tucoulou R, Marx U, Perka C, Duda GN, Geissler S (2020) Metal-specific biomaterial accumulation in human peri-implant bone and bone marrow. Adv Sci (Weinh) 7(20):2000412PubMedPubMedCentralCrossRef Schoon J, Hesse B, Rakow A, Ort MJ, Lagrange A, Jacobi D, Winter A, Huesker K, Reinke S, Cotte M, Tucoulou R, Marx U, Perka C, Duda GN, Geissler S (2020) Metal-specific biomaterial accumulation in human peri-implant bone and bone marrow. Adv Sci (Weinh) 7(20):2000412PubMedPubMedCentralCrossRef
48.
Zurück zum Zitat Handorn B (2021) Die Medizinprodukte-Verordnung (EU) 2017/745: Ein Leitfaden für Wirtschaftsakteure zur MDR. Beuth, Berlin Handorn B (2021) Die Medizinprodukte-Verordnung (EU) 2017/745: Ein Leitfaden für Wirtschaftsakteure zur MDR. Beuth, Berlin
49.
Zurück zum Zitat Thangaraju P, Varthya SB (2022) ISO 10993: biological evaluation of medical devices. In: Medical device guidelines and regulations handbook. Springer, Cham, pp 163–187CrossRef Thangaraju P, Varthya SB (2022) ISO 10993: biological evaluation of medical devices. In: Medical device guidelines and regulations handbook. Springer, Cham, pp 163–187CrossRef
50.
Zurück zum Zitat Matharu GS, Pynsent PB, Dunlop DJ (2014) Revision of metal-on-metal hip replacements and resurfacings for adverse reaction to metal debris: a systematic review of outcomes. HIP Int 24(4):311–320PubMedCrossRef Matharu GS, Pynsent PB, Dunlop DJ (2014) Revision of metal-on-metal hip replacements and resurfacings for adverse reaction to metal debris: a systematic review of outcomes. HIP Int 24(4):311–320PubMedCrossRef
51.
Zurück zum Zitat Martiniakova M, Grosskopf B, Omelka R, Vondrakova M, Bauerova M (2006) Differences among species in compact bone tissue microstructure of mammalian skeleton: use of a discriminant function analysis for species identification. J Forensic Sci 51(6):1235–1239PubMedCrossRef Martiniakova M, Grosskopf B, Omelka R, Vondrakova M, Bauerova M (2006) Differences among species in compact bone tissue microstructure of mammalian skeleton: use of a discriminant function analysis for species identification. J Forensic Sci 51(6):1235–1239PubMedCrossRef
52.
Zurück zum Zitat Trommer RM, Maru MM (2017) Importance of preclinical evaluation of wear in hip implant designs using simulator machines. Rev Bras Ortop 52(3):251–259PubMedCrossRef Trommer RM, Maru MM (2017) Importance of preclinical evaluation of wear in hip implant designs using simulator machines. Rev Bras Ortop 52(3):251–259PubMedCrossRef
53.
Zurück zum Zitat Czekanska EM, Stoddart MJ, Ralphs JR, Richards RG, Hayes JS (2014) A phenotypic comparison of osteoblast cell lines versus human primary osteoblasts for biomaterials testing. J Biomed Mater Res A 102(8):2636–2643PubMedCrossRef Czekanska EM, Stoddart MJ, Ralphs JR, Richards RG, Hayes JS (2014) A phenotypic comparison of osteoblast cell lines versus human primary osteoblasts for biomaterials testing. J Biomed Mater Res A 102(8):2636–2643PubMedCrossRef
54.
Zurück zum Zitat Schweitzer L, Cunha A, Pereira T, Mika K, Botelho do Rego AM, Ferraria AM, Kieburg H, Geissler S, Uhlmann E, Schoon J (2020) Preclinical in vitro assessment of submicron-scale laser surface texturing on Ti6Al4V. Materials (Basel) 13(23):5342PubMedCrossRef Schweitzer L, Cunha A, Pereira T, Mika K, Botelho do Rego AM, Ferraria AM, Kieburg H, Geissler S, Uhlmann E, Schoon J (2020) Preclinical in vitro assessment of submicron-scale laser surface texturing on Ti6Al4V. Materials (Basel) 13(23):5342PubMedCrossRef
55.
Zurück zum Zitat Andrzejewska A, Catar R, Schoon J, Qazi TH, Sass FA, Jacobi D, Blankenstein A, Reinke S, Kruger D, Streitz M, Schlickeiser S, Richter S, Souidi N, Beez C, Kamhieh-Milz J, Kruger U, Zemojtel T, Jurchott K, Strunk D, Reinke P, Duda G, Moll G, Geissler S (2019) Multi-parameter analysis of biobanked human bone marrow stromal cells shows little influence for donor age and mild comorbidities on phenotypic and functional properties. Front Immunol 10:2474PubMedPubMedCentralCrossRef Andrzejewska A, Catar R, Schoon J, Qazi TH, Sass FA, Jacobi D, Blankenstein A, Reinke S, Kruger D, Streitz M, Schlickeiser S, Richter S, Souidi N, Beez C, Kamhieh-Milz J, Kruger U, Zemojtel T, Jurchott K, Strunk D, Reinke P, Duda G, Moll G, Geissler S (2019) Multi-parameter analysis of biobanked human bone marrow stromal cells shows little influence for donor age and mild comorbidities on phenotypic and functional properties. Front Immunol 10:2474PubMedPubMedCentralCrossRef
56.
Zurück zum Zitat Grotenhuis N, Vd Toom HF, Kops N, Bayon Y, Deerenberg EB, Mulder IM, van Osch GJ, Lange JF, Bastiaansen-Jenniskens YM (2014) In vitro model to study the biomaterial-dependent reaction of macrophages in an inflammatory environment. Br J Surg 101(8):983–992PubMedCrossRef Grotenhuis N, Vd Toom HF, Kops N, Bayon Y, Deerenberg EB, Mulder IM, van Osch GJ, Lange JF, Bastiaansen-Jenniskens YM (2014) In vitro model to study the biomaterial-dependent reaction of macrophages in an inflammatory environment. Br J Surg 101(8):983–992PubMedCrossRef
57.
Zurück zum Zitat Kodzius R, Schulze F, Gao X, Schneider MR (2017) Organ-on-chip technology: current state and future developments. Genes (Basel) 8(10):266PubMedCrossRef Kodzius R, Schulze F, Gao X, Schneider MR (2017) Organ-on-chip technology: current state and future developments. Genes (Basel) 8(10):266PubMedCrossRef
Metadaten
Titel
Noninfectious tissue interactions at periprosthetic interfaces
verfasst von
Dr. Frank Schulze
Giorgio Perino, MD
Anastasia Rakow, MD
Prof. Dr. Georgi Wassilew
Dr. Janosch Schoon
Publikationsdatum
28.02.2023
Verlag
Springer Medizin
Erschienen in
Die Orthopädie / Ausgabe 3/2023
Print ISSN: 2731-7145
Elektronische ISSN: 2731-7153
DOI
https://doi.org/10.1007/s00132-023-04352-y

Weitere Artikel der Ausgabe 3/2023

Die Orthopädie 3/2023 Zur Ausgabe

CME Zertifizierte Fortbildung

Osteoporose: Diagnostik und Behandlung

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Mehr Frauen im OP – weniger postoperative Komplikationen

21.05.2024 Allgemeine Chirurgie Nachrichten

Ein Frauenanteil von mindestens einem Drittel im ärztlichen Op.-Team war in einer großen retrospektiven Studie aus Kanada mit einer signifikanten Reduktion der postoperativen Morbidität assoziiert.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

Klinikreform soll zehntausende Menschenleben retten

15.05.2024 Klinik aktuell Nachrichten

Gesundheitsminister Lauterbach hat die vom Bundeskabinett beschlossene Klinikreform verteidigt. Kritik an den Plänen kommt vom Marburger Bund. Und in den Ländern wird über den Gang zum Vermittlungsausschuss spekuliert.

TEP mit Roboterhilfe führt nicht zu größerer Zufriedenheit

15.05.2024 Knie-TEP Nachrichten

Der Einsatz von Operationsrobotern für den Einbau von Totalendoprothesen des Kniegelenks hat die Präzision der Eingriffe erhöht. Für die postoperative Zufriedenheit der Patienten scheint das aber unerheblich zu sein, wie eine Studie zeigt.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.