Erschienen in:
01.12.2012 | Original Contribution
Prevalence of hypovitaminosis D and folate deficiency in healthy young female Austrian students in a health care profession
verfasst von:
Stefan T. Kaehler, Holger Baumgartner, Martina Jeske, Markus Anliker, Harald Schennach, Peter Marschang, Anna Ratt, Anna C. Colvin, Jennifer Falk, Astrid Gasser, Julia Kirchebner, Christine Scherer, Anna E. Purtscher, Andrea Griesmacher, Jörg Striessnig
Erschienen in:
European Journal of Nutrition
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Ausgabe 8/2012
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Abstract
Purpose
We performed a single-day cross-sectional study to assess the prevalence of vitamin D deficiency as well as folate status in healthy young female volunteers well educated with respect to health information.
Methods
We assessed dietary intake of vitamin D and calcium, serum concentrations of 25-OH-vitamin D3, folate, red blood cell folate and other dietary, laboratory, and lifestyle parameters in 215 young healthy women (age 18–30 years) on a single day at the end of the winter months. Primary aim was to investigate the prevalence of hypovitaminosis D. Folic acid status was a secondary study aim.
Results
Mean daily ingestion of vitamin D was 2.25 μg/day with a daily calcium intake of 749 mg/day. 6.9% had hypovitaminosis D (25-OH-vitamin D3 <30 nmol/L) and 89.3% were vitamin D insufficient (<75 nmol/L). Preplanned subpopulation comparison (lower vs. upper quartile) revealed a significant negative correlation (P = 0.048) between plasma PTH and 25-OH-vitamin D3 levels. Fifteen individuals (6.9%) were folic acid deficient (<140 ng/mL RBC folate). Only 9.3% reached RBC folate concentrations regarded as optimal for the prevention of fetal neural tube defects (>400 ng/mL).
Conclusions
The prevalence of hypovitaminosis D in healthy young women trained in health care professions is low but 89.3% can be classified as vitamin D insufficient in spring. Folate status can also be considered not sufficient. Considering the emerging role of higher vitamin D plasma levels for many health conditions, a timely correction of vitamin D status in the general Austrian population appears appropriate.