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Arthritis Research & Therapy

Ausgabe 5/2011

Inhalt (55 Artikel)

Review

Dupuytren's: a systems biology disease

Samrina Rehman, Royston Goodacre, Philip J Day, Ardeshir Bayat, Hans V Westerhoff

Review

Celecoxib: considerations regarding its potential disease-modifying properties in osteoarthritis

Manon C Zweers, Tineke N de Boer, Joël van Roon, Johannes WJ Bijlsma, Floris PJG Lafeber, Simon C Mastbergen

Review

Osteoimmunology and osteoporosis

Piet Geusens, Willem F Lems

Editorial

Bisphosphonates for osteoarthritis

David A Walsh, Victoria Chapman

Open Access Research article

Ossification process involving the human thoracic ligamentum flavum: role of transcription factors

Kenzo Uchida, Takafumi Yayama, Hong-Xin Cai, Hideaki Nakajima, Daisuke Sugita, Alexander Rodríguez Guerrero, Shigeru Kobayashi, Ai Yoshida, Ke-Bing Chen, Hisatoshi Baba

Open Access Research article

Biomechanical signals and the C-type natriuretic peptide counteract catabolic activities induced by IL-1β in chondrocyte/agarose constructs

Manoj Ramachandran, Prim Achan, Donald M Salter, Dan L Bader, Tina T Chowdhury

Open Access Research article

A new category of autoinflammatory disease associated with NOD2 gene mutations

Qingping Yao, Lan Zhou, Philip Cusumano, Nilanjana Bose, Melissa Piliang, Bijal Jayakar, Le-Chu Su, Bo Shen

Editorial

Pus: the Rodney Dangerfield of immunology

David S Pisetsky

Open Access Research article

Binding immunoglobulin protein resolves rheumatoid synovitis: a xenogeneic study using rheumatoid arthritis synovial membrane transplants in SCID mice

Kaoru Yoshida, Akira Ochiai, Hiroaki Matsuno, Gabriel S Panayi, Valerie M Corrigall

Open Access Research article

Integrated safety in tocilizumab clinical trials

Michael H Schiff, Joel M Kremer, Angelika Jahreis, Emma Vernon, John D Isaacs, Ronald F van Vollenhoven

Open Access Research article

Prostaglandin E2 receptor type 2-selective agonist prevents the degeneration of articular cartilage in rabbit knees with traumatic instability

Hiroto Mitsui, Tomoki Aoyama, Moritoshi Furu, Kinya Ito, Yonghui Jin, Takayuki Maruyama, Toshiya Kanaji, Shinsei Fujimura, Hikaru Sugihara, Akio Nishiura, Takanobu Otsuka, Takashi Nakamura, Junya Toguchida

Open Access Research article

Improved responsiveness and reduced sample size requirements of PROMIS physical function scales with item response theory

James F Fries, Eswar Krishnan, Matthias Rose, Bharathi Lingala, Bonnie Bruce

Open Access Research article

A validity-driven approach to the understanding of the personal and societal burden of low back pain: development of a conceptual and measurement model

Rachelle Buchbinder, Roy Batterham, Gerald Elsworth, Clermont E Dionne, Emma Irvin, Richard H Osborne

Open Access Research article

Aberrant splicing of the hRasGRP4 transcript and decreased levels of this signaling protein in the peripheral blood mononuclear cells in a subset of patients with rheumatoid arthritis

Toko Hashimoto, Shinsuke Yasuda, Hideyuki Koide, Hiroshi Kataoka, Tetsuya Horita, Tatsuya Atsumi, Takao Koike

Open Access Research article

Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus

Sebastian Dolff, Wayel H Abdulahad, Johanna Westra, Berber Doornbos-van der Meer, Pieter C Limburg, Cees GM Kallenberg, Marc Bijl

Open Access Research article

Chemerin activates fibroblast-like synoviocytes in patients with rheumatoid arthritis

Kayoko Kaneko, Yoshishige Miyabe, Aiko Takayasu, Shin Fukuda, Chie Miyabe, Masashi Ebisawa, Waka Yokoyama, Kaori Watanabe, Toshio Imai, Kenzo Muramoto, Yuya Terashima, Takahiko Sugihara, Kouji Matsushima, Nobuyuki Miyasaka, Toshihiro Nanki

Review

Lupus nephritis: current update

Ramesh Saxena, Tina Mahajan, Chandra Mohan

Review

Mechanisms of B cell autoimmunity in SLE

Thomas Dörner, Claudia Giesecke, Peter E Lipsky

Review

Integrins and their ligands in rheumatoid arthritis

Torsten Lowin, Rainer H Straub

Open Access Research article

RETRACTED ARTICLE: Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium

Jolien Suurmond, Annemarie L Dorjée, Mariëtte R Boon, Edward F Knol, Tom WJ Huizinga, René EM Toes, Annemie JM Schuerwegh

Open Access Research article

Texture analysis of cartilage T2 maps: individuals with risk factors for OA have higher and more heterogeneous knee cartilage MR T2 compared to normal controls - data from the osteoarthritis initiative

Gabby B Joseph, Thomas Baum, Julio Carballido-Gamio, Lorenzo Nardo, Warapat Virayavanich, Hamza Alizai, John A Lynch, Charles E McCulloch, Sharmila Majumdar, Thomas M Link

Open Access Research article

Human epidermal growth factor receptor bispecific ligand trap RB200: abrogation of collagen-induced arthritis in combination with tumour necrosis factor blockade

Luke L Gompels, Nasser M Malik, Leigh Madden, Pei Jin, Marc Feldmann, H Michael Shepard, Ewa M Paleolog

Open Access Research article

Bone destruction by receptor activator of nuclear factor κB ligand-expressing T cells in chronic gouty arthritis

Sung-Ji Lee, Kwang-Il Nam, Hye-Mi Jin, Young-Nan Cho, Song-Eun Lee, Tae-Jong Kim, Shin-Seok Lee, Seung-Jung Kee, Keun-Bae Lee, Nacksung Kim, Yong-Wook Park

Open Access Research article

Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes in systemic sclerosis: association with interstitial lung disease

Marie-Elise Truchetet, Nicolò C Brembilla, Elisa Montanari, Yannick Allanore, Carlo Chizzolini

Open Access Research article

Effectiveness of cognitive behaviour therapy for the treatment of catastrophisation in patients with fibromyalgia: a randomised controlled trial

Marta Alda, Juan V Luciano, Eva Andrés, Antoni Serrano-Blanco, Baltasar Rodero, Yolanda López del Hoyo, Miquel Roca, Sergio Moreno, Rosa Magallón, Javier García-Campayo

Open Access Research article

A five-year prospective study of fatigue in primary Sjögren's syndrome

Karstein Haldorsen, Ingvar Bjelland, Anne Isine Bolstad, Roland Jonsson, Johan Gorgas Brun

Open Access Research article

Fragment of tegument protein pp65 of human cytomegalovirus induces autoantibodies in BALB/c mice

Ao-Ho Hsieh, Yí-Jyun Jhou, Chung-Ting Liang, Mingi Chang, Shih-Lien Wang

Open Access Research article

The rat intervertebral disk degeneration pain model: relationships between biological and structural alterations and pain

Jae-Sung Kim, Jeffrey S Kroin, Xin Li, Howard S An, Asokumar Buvanendran, Dongyao Yan, Kenneth J Tuman, Andre J van Wijnen, Di Chen, Hee-Jeong Im

Open Access Research article

Associations of educational attainment, occupation and community poverty with knee osteoarthritis in the Johnston County (North Carolina) osteoarthritis project

Leigh F Callahan, Rebecca J Cleveland, Jack Shreffler, Todd A Schwartz, Britta Schoster, Randy Randolph, Jordan B Renner, Joanne M Jordan

Open Access Research article

Regulatory mechanisms for the production of BAFF and IL-6 are impaired in monocytes of patients of primary Sjögren's syndrome

Keiko Yoshimoto, Maiko Tanaka, Masako Kojima, Yumiko Setoyama, Hideto Kameda, Katsuya Suzuki, Kensei Tsuzaka, Yoko Ogawa, Kazuo Tsubota, Tohru Abe, Tsutomu Takeuchi

Open Access Research article

Impact of interleukin-21 in the pathogenesis of primary Sjogren's syndrome: increased serum levels of interleukin-21 and its expression in the labial salivary glands

Kwi Young Kang, Hyun-Ok Kim, Seung-Ki Kwok, Ji Hyeon Ju, Kyung-Su Park, Dong-Il Sun, Joo Yeon Jhun, Hye Jwa Oh, Sung-Hwan Park, Ho-Youn Kim

Open Access Research article

Can anti-cyclic citrullinated peptide antibody-negative RA be subdivided into clinical subphenotypes?

Diederik PC De Rooy, Annemiek Willemze, Bart Mertens, Tom WJ Huizinga, Annette HM Van der Helm-van Mil

Open Access Research article

Seropositivity is associated with insulin resistance in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register (NOAR): an observational study

Hoda Mirjafari, Tracey M Farragher, Suzanne MM Verstappen, Allen Yates, Diane Bunn, Tarnya Marshall, Mark Lunt, Deborah PM Symmons, Ian N Bruce

Open Access Research article

Aberrant axial mineralization precedes spinal ankylosis: a molecular imaging study in ank/ankmice

Facundo Las Heras, Ralph S DaCosta, Kenneth PH Pritzker, Nigil Haroon, George Netchev, Hing Wo Tsui, Basil Chiu, W Mark Erwin, Florence WL Tsui, Robert D Inman

Open Access Research article

An organ culture system to model early degenerative changes of the intervertebral disc

Ravi K Ponnappan, Dessislava Z Markova, Paul JD Antonio, Hallie B Murray, Alexander R Vaccaro, Irving M Shapiro, D Greg Anderson, Todd J Albert, Makarand V Risbud

Open Access Research article

Soluble receptor activator of nuclear factor κB ligand/osteoprotegerin ratio is increased in systemic lupus erythematosus patients

Diana Carmona-Fernandes, Maria José Santos, Inês Pedro Perpétuo, João Eurico Fonseca, Helena Canhão

Open Access Research article

Quantification of the whole-body burden of radiographic osteoarthritis using factor analysis

Amanda E Nelson, Robert F DeVellis, Jordan B Renner, Todd A Schwartz, Philip G Conaghan, Virginia B Kraus, Joanne M Jordan

Open Access Research article

The use, safety, and effectiveness of herpes zoster vaccination in individuals with inflammatory and autoimmune diseases: a longitudinal observational study

Jie Zhang, Elizabeth Delzell, Fenglong Xie, John W Baddley, Claire Spettell, Raechele M Mcmahan, Joaquim Fernandes, Lang Chen, Kevin Winthrop, Jeffrey R Curtis

Open Access Research article

MTRX1011A, a humanized anti-CD4 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a Phase I randomized, double-blind, placebo-controlled study incorporating pharmacodynamic biomarker assessments

Heleen Scheerens, Zheng Su, Bryan Irving, Michael J Townsend, Yanan Zheng, Eric Stefanich, Vishala Chindalore, Clifton O Bingham III, John C Davis Jr

Open Access Research article

Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis

Jeffrey R Curtis, John W Baddley, Shuo Yang, Nivedita Patkar, Lang Chen, Elizabeth Delzell, Ted R Mikuls, Kenneth G Saag, Jasvinder Singh, Monika Safford, Grant W Cannon

Open Access Research article

Frequency of disease-associated and other nuclear autoantibodies in patients of the German network for systemic scleroderma: correlation with characteristic clinical features

Rudolf Mierau, Pia Moinzadeh, Gabriela Riemekasten, Inga Melchers, Michael Meurer, Frank Reichenberger, Michael Buslau, Margitta Worm, Norbert Blank, Rüdiger Hein, Ulf Müller-Ladner, Annegret Kuhn, Cord Sunderkötter, Aaron Juche, Christiane Pfeiffer, Christoph Fiehn, Michael Sticherling, Percy Lehmann, Rudolf Stadler, Eckhard Schulze-Lohoff, Cornelia Seitz, Ivan Foeldvari, Thomas Krieg, Ekkehard Genth, Nicolas Hunzelmann

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