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6502 Suchergebnisse für:

Dermatomyositis 

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  1. Open Access 01.12.2023 | OriginalPaper

    Rapid and sustained response to JAK inhibition in a child with severe MDA5 + juvenile dermatomyositis

    Juvenile dermatomyositis (jDM) is the most common idiopathic inflammatory myopathy of childhood [ 1 ]. This systemic autoimmune disease is associated with typical changes in the skin, vasculopathy, and muscle weakness that is usually trunk …

  2. 02.08.2023 | OriginalPaper

    Increased serum soluble interleukin-2 receptor levels in dermatomyositis are associated with Th17/Treg immune imbalance

    Dermatomyositis (DM) represents a multifaceted chronic inflammatory myopathy, primarily manifesting as progressive deterioration of muscular and cutaneous tissues. Despite an incomplete comprehension of DM's etiology and pathogenesis, current …

  3. 31.08.2023 | Online First

    Anti-TIF-1γ Positive Juvenile Dermatomyositis Diagnosed with Atopic Dermatitis

  4. 12.05.2023 | DDG-Tagung 2023 | Nachrichten | Online-Artikel
    Neue Therapien

    Dermatomyositis: Es tut sich was

    Zum ersten Mal seit Längerem befinden sich zeitgleich zahlreiche neue Wirkstoffe für die Behandlung von Patienten mit Dermatomyositis in der klinischen Erprobung.

  5. 06.09.2023 | Online First

    Nontuberculous mycobacterial myositis in dermatomyositis with long-term use of immunosuppressant: a case report

    Inflammatory myopathies, such as polymyositis and dermatomyositis, are systemic inflammatory disorders that affect skeletal muscles and internal organs. The treatment of inflammatory myopathies usually involves long-term use of high doses of …

  6. 08.09.2023 | Online First

    Successful management of interstitial lung disease in dermatomyositis complicated by malignancy: a case-based review

    Dermatomyositis (DM) is associated with interstitial lung disease (ILD) and malignancy. However, the coexistence of ILD and malignancy (DM–ILD–malignancy) is rare, and limited information exists regarding its management. Herein, we report the case …

  7. 05.06.2023 | BriefCommunication

    [68Ga]Ga-FAPI-04 and [18F]FDG PET/ CT in a patient with MDA5 dermatomyositis

  8. Open Access 01.12.2023 | OriginalPaper

    Spontaneous intramuscular hemorrhage in cancer-associated dermatomyositis: a case and literature review

    Dermatomyositis (DM), one kind of idiopathic inflammatory myopathy (IIM), is a systemic autoimmune disease with characteristic cutaneous manifestations and muscle weakness of the trunk and symmetrical proximal muscles of the limbs. Characteristic …

  9. Open Access 01.12.2023 | OriginalPaper

    Ground-glass opacity score predicts the prognosis of anti-MDA5 positive dermatomyositis: a single-centre cohort study

    Anti-MDA5-DM is a systemic autoimmune disease with high mortality. Interstitial lung disease (ILD) is a common complication and a leading cause of death [ 1 ]. Anti-MDA5 antibody was a risk factor for rapidly progressive ILD (RPILD) [ 2 , 3 ]. The …

  10. Open Access 01.12.2023 | OriginalPaper

    Currently recommended skin scores correlate highly in the assessment of patients with Juvenile Dermatomyositis (JDM)

    Although childhood rheumatic diseases are currently not curable, they are treatable. The development of standardized outcome measures has been pivotal in assessing and following response to treatment.

  11. 16.04.2023 | Report

    The physical and emotional impact of cutaneous dermatomyositis: a qualitative study

    Dermatomyositis (DM) is a rare autoimmune disease characterized by distinctive cutaneous manifestations, often accompanied by muscle inflammation and interstitial lung disease. DM has a significant impact on quality of life (QoL) in patients, due …

  12. Open Access 01.12.2023 | OriginalPaper

    Mortality risk in patients with anti-MDA5 dermatomyositis is related to rapidly progressive interstitial lung disease and anti-Ro52 antibody

    Dermatomyositis (DM) is a systemic, heterogeneous disease that presents with skeletal muscle weakness, typical skin lesions, and other internal organ damage, usually with specific autoantibodies. The autoantibody against melanoma …

  13. 31.05.2023 | EditorialNotes

    Ulcerative rash in a patient with anti-MDA5 antibody-associated clinically amyopathic dermatomyositis

    A man in his sixties presented with recurrent rash for 10 years and joint pain for 3 years. The red macular rash appeared repeatedly on the periorbital, cheeks, ears, chest, neck, and extremities. Recurrent skin ruptures on both auricles and hands …

  14. 11.07.2023 | Online First

    Risk factors for developing calcinosis in juvenile dermatomyositis: subcutaneous and myofascial edema in initial magnetic resonance imaging

    Calcinosis is a sequela of Juvenile Dermatomyositis (JDM) with significant morbidity. A retrospective study observing risk factors for JDM calcinosis, including a possible association between higher intensity of subcutaneous and myofascial edema …

  15. 01.05.2023 | ReviewPaper

    Dermatomyositis Diagnosis and Treatment in the Inpatient Setting

    Dermatomyositis (DM) is an idiopathic inflammatory myopathy that classically presents with characteristic cutaneous features and muscle inflammation, although approximately 20% of patients present with skin involvement alone [ 1 ]. This condition …

  16. 24.02.2023 | EditorialNotes

    Bone within bone in juvenile dermatomyositis

    Twenty-eight-year-old woman with juvenile dermatomyositis (JDM) since 7 years old who was taking immunosuppressive therapy (azathioprine 100 mg/day and mycophenolate mofetil 3 g/day) presented as an asymptomatic patient for a rheumatology …

  17. Open Access 01.12.2023 | OriginalPaper

    Rapidly progressive interstitial lung disease combined with pneumocystis jiroveci pneumonia in a patient with single anti-TIF-1γ antibody positive dermatomyositis in the context of an underlying tumor

    Dermatomyositis (DM) is a chronic autoimmune disease that commonly affects multiple organs, including the skin, transverse muscles, and lungs. The pathology of DM is characterized by tissue infiltration of inflammatory cells [ 1 , 2 ]. Clinical …

  18. Open Access 01.12.2023 | OriginalPaper

    Enhanced immune complex formation in the lungs of patients with dermatomyositis

    Idiopathic inflammatory myopathies (IIMs) are rare autoimmune diseases [ 1 ]. Dermatomyositis is an IIM subtype presenting with proximal skeletal muscle weakness and muscle inflammation. Dermatomyositis is characterized by skin disorders, including …

  19. Open Access 01.12.2023 | OriginalPaper

    Identification of key biomarkers associated with immune cells infiltration for myocardial injury in dermatomyositis by integrated bioinformatics analysis

    Dermatomyositis (DM) is an acquired autoimmune disease in which skeletal muscle is targeted by the immune system, which is a subset of idiopathic inflammatory myopathy (IIM) [ 1 ]. DM is characterized primarily by muscle inflammation, proximal …

  20. 09.05.2023 | OriginalPaper

    Plasma proteomic profiling reveals KRT19 could be a potential biomarker in patients with anti-MDA5+ dermatomyositis

    Idiopathic inflammatory myopathies (IIMs) are heterogeneous disorders with muscle inflammation, cutaneous manifestations, lung involvement, and arthritis [ 1 ]. Muscle weakness is present in most of IIM patients, extra-muscular involvement often …

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