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6502 Suchergebnisse für:

Dermatomyositis 

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  1. 01.06.2006 | ReviewPaper

    Hydroxychloroquine-Induced Retinopathy

    A Dermatologic Perspective

    Dermatologists use antimalarials to treat conditions such as cutaneous lupus erythematosus. One potentially serious adverse effect of these agents is irreversible maculopathy. Although there is some evidence that hydroxychloroquine and chloroquine …

  2. 01.12.2009 | OriginalPaper

    Cutaneous Lupus Erythematosus

    Issues in Diagnosis and Treatment

    Cutaneous lupus erythematosus (LE) may present in a variety of clinical forms. Three recognized subtypes of cutaneous LE are acute cutaneous LE (ACLE), subacute cutaneous LE (SCLE), and chronic cutaneous LE (CCLE). ACLE may be localized (most …

  3. 01.12.2008 | OriginalPaper

    Skin Manifestations of Lyme Borreliosis

    Diagnosis and Management

    Lyme borreliosis is a multisystem infectious disease caused by tick-transmitted spirochetes of the Borrelia burgdorferi sensu lato complex. The three characteristic cutaneous manifestations are erythema migrans, borrelial lymphocytoma, and …

  4. 01.10.2010 | ReviewPaper

    Intravenous Immunoglobulin Therapy in Autoimmune Mucocutaneous Blistering Diseases

    A Review of the Evidence for its Efficacy and Safety

    Intravenous immunoglobulin (IVIg) is a biologic agent that is being increasingly used in the treatment of autoimmune and chronic inflammatory disorders. It is approved by the US FDA for the treatment of primary immunodeficiencies, immune …

  5. 01.04.2010 | ReviewPaper

    The Purple Digit

    An Algorithmic Approach to Diagnosis

    The acute onset of purple digits is a concerning manifestation and may represent underlying, potentially life-threatening disease. Correctly identifying the etiology of purple digits is essential to proper management, and can aid in the diagnosis …

  6. 01.07.2012 | Report

    Paraneoplastic neurological syndrome presenting as difficulty in mouth opening in a patient with small cell lung cancer

    A 60-year-old man was admitted to our hospital experiencing difficulty in opening his mouth, and diplopia. Chest computed tomography showed a mass on the right lung. Transbronchial biopsy and scrutiny of the whole body resulted in the diagnosis of …

  7. 01.06.2011 | OriginalPaper

    A case of spontaneous submucosal dissection of the esophagus

    We report a case of spontaneous submucosal dissection of the esophagus of a 58-year-old patient. In September 2005, he complained of chest pain followed by vomiting. Endoscopy showed an ulcerative lesion in the entire circumference of the middle …

  8. 01.02.2009 | OriginalPaper

    The spectrum of Susac’s syndrome

    We report a series of four patients with Susac’s syndrome, which is characterized by the triad of visual loss due to branch retinal artery occlusions, sensorineural hearing loss due to cochlear involvement, and encephalopathy due to cerebral …

  9. 01.01.2001 | Abstract

    Abstract

  10. 01.10.2003 | OriginalPaper

    Antibodies and myelination: facts and misacts

    Polyreactive (auto)antibodies are frequently found in healthy subjects and are bona fide considered to be nonpathogenic. However, autoreactive B cells and circulating (auto)antibodies have been associated with several neurological syndromes …

  11. 01.10.2011 | OriginalPaper

    Pilot trial of simvastatin in the treatment of sporadic inclusion-body myositis

    Sporadic inclusion-body myositis (s-IBM) is a chronic progressive inflammatory myopathy leading to severe disability. It has been suggested that statins may benefit s-IBM patients based on their pleiotropic effects on autoimmunity and possible …

  12. 01.04.2005 | OriginalPaper

    Proceedings, 33rd European Symposium on Clinical Pharmacy: Risk Management in Pharmacotherapy

  13. 01.02.1997 | OriginalPaper

    Part 2: Pharmacology of neuromuscular blocking agents

    Clinically, neuromuscular blockade is induced with either depolarizing or non‐depolarizing relaxants. Suxamethonium is the only depolarizing relaxant still in use. It is hydrolysed in the plasma by pseudo‐cholinesterase (plasma cholinesterase). In …

  14. 01.12.2000 | OriginalPaper

    Clinical significance of ventilation/perfusion scans in collagen disease patients

    The purpose of this study was to detect disturbances in pulmonary circulation in collagen disease patients by means of a non-invasive technique.Methods: Ventilation/perfusion scans with133Xe gas and99mTc-macroaggregated albumin (MAA) were …

  15. 01.10.2003 | OriginalPaper

    Intravenous immunoglobulins in neurological disorders: safety issues

    IVIg products may be applied for the provision of antibodies in patients with primary or secondary antibody deficiency syndromes or with the aim of immune modulation in patients with autoimmune diseases. The average dose for the provision of …

  16. 01.02.2006 | OriginalPaper

    An unbiased and efficient computerised tomography method to quantify muscle and adipose tissue volume in neuromuscular patients

    The objective was to evaluate the applicability and reliability of an unbiased stereological computerised tomography (CT) method for estimating total human body (HB), skeletal muscle (SM) and adipose tissue (AT) volumes in groups of neuromuscular …

  17. 01.09.2013 | OriginalPaper

    Caregiver Demand and Parent Distress in Juvenile Rheumatic Disease: The Mediating Effect of Parent Attitude Toward Illness

    Parents of youth with juvenile rheumatic diseases (JRD) often take on illness management responsibilities that can become burdensome, potentially resulting in poor parent adjustment outcomes. However, not all caregivers will experience increased …

  18. 01.08.2014 | OriginalPaper

    ‘Neuroinflammation’ differs categorically from inflammation: transcriptomes of Alzheimer's disease, Parkinson's disease, schizophrenia and inflammatory diseases compared

    ‘Neuroinflammation’ has become a widely applied term in the basic and clinical neurosciences but there is no generally accepted neuropathological tissue correlate. Inflammation, which is characterized by the presence of perivascular infiltrates of …

  19. 01.04.2009 | OriginalPaper

    Familial risks for amyotrophic lateral sclerosis and autoimmune diseases

    Population-level familial risks are not available for amyotrophic lateral sclerosis (ALS), and a few studies have analyzed familial association of ALS with other diseases. We used the Swedish Multigeneration Register to identify family members and …

  20. 01.02.2009 | OriginalPaper

    Risk for multiple sclerosis in relatives and spouses of patients diagnosed with autoimmune and related conditions

    In the era of complex disease genetics, the consideration of familial risks is important in the assessment of the likely success of these studies. In the present article, we study familial risks for multiple sclerosis (MS) among parents and …

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