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Leukemia

Recent Developments in Diagnosis and Therapy

  • Book
  • © 1984

Overview

Editors:
  1. Eckhard Thiel

    1. Institut für Hämatologie, Abteilung für Immunologie, Gesellschaft für Strahlen- und Umweltforschung mbH, München 2, Germany

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  2. Stephan Thierfelder

    1. Institut für Hämatologie, Abteilung für Immunologie, Gesellschaft für Strahlen- und Umweltforschung mbH, München 2, Germany

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Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 93)

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Table of contents (13 chapters)

  1. Front Matter

    Pages I-IX
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  2. Current Understanding of Virus Etiology in Leukemia

    • R. Hehlmann, H. Schetters, C. Leib-Mösch, V. Erfle
    Pages 1-28

  3. Cytogenetics in Leukemia: Implications for Pathogenesis and Prognosis

    • D. K. Hossfeld, H.-J. Weh
    Pages 29-50

  4. Morphology, Cytochemistry, and Ultrastructure of Leukemic Cells with Regard to the Classification of Leukemias

    • D. Huhn
    Pages 51-68

  5. “Atypical” Leukemias: Preleukemia, Smoldering Leukemia and Hypoplastic Leukemia

    • D. Hoelzer, A. Ganser, H. Heimpel
    Pages 69-101

  6. Biological and Clinical Significance of Immunological Cell Markers in Leukemia

    • E. Thiel
    Pages 102-158

  7. Acute Lymphoblastic Leukemia: Current Status of Therapy in Children

    • F. Lampert, G. Henze, H.-J. Langermann, G. Schellong, H. Gadner, H.-J. Riehm
    Pages 159-181

  8. Current Status of ALL/AUL Therapy in Adults

    • D. Hoelzer
    Pages 182-203

  9. Acute Myelogenous Leukemia: Current Status of Therapy in Children

    • J. Ritter, U. Creutzig, H.-J. Riehm, G. Schellong
    Pages 204-215

  10. Acute Myelogenous Leukemia: Current Status of Therapy in Adults

    • K. A. Foon, R. P. Gale
    Pages 216-239

  11. Management of CLL and Allied Disorders with Reference to Their Immunology and Proliferation Kinetics

    • H. Theml, H. W. L. Ziegler-Heitbrock
    Pages 240-258

  12. Management of Chronic Myelogenous Leukemia and Blastic Crisis

    • K. P. Hellriegel
    Pages 259-268

  13. Allogeneic Bone Marrow Transplantation in Leukemia

    • H.-J. Kolb
    Pages 269-289

  14. Autologous Bone Marrow Transplantation in Leukemia

    • B. Netzel, R. I. Haas, S. Thierfelder
    Pages 290-300

  15. Back Matter

    Pages 301-308
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Keywords

About this book

Much of the attention presently paid to leukemia is the result of recent progress in understanding and treatment. Chemotherapy of leukemia started in the late 1940s, and combination therapy evolved in the late 1950s. It was at that time that the clonality of leukemia was realized, after the discovery of chromosomal and then biochemical and immunological markers. And now we have the new data on retroviral and cellular oncogenes and the reports on human T -cell lymphoma/ leukemia viruses. Many more steps forward could be enumerated in a field which is so rapidly making the hematological textbooks outdated. In this volume, thirteen in-depth reviews from large multicenter trials in the Federal Republic of Germany summarize the current state of diagnosis and management of leukemias. Childhood ALL and AML adult ALL and AUL were investigated. While cure appears to be achievable for more and more patients with acute leukemia, we still pursue the aim of optimal palliation in chronic leukemias. The management of patients with leukemia therefore varies to a large extent in aggressiveness of therapy. In some situations, rescue from an otherwise lethal disease is provided by bone marrow transplanta­ tion, which is discussed in two chapters.

Editors and Affiliations

  • Institut für Hämatologie, Abteilung für Immunologie, Gesellschaft für Strahlen- und Umweltforschung mbH, München 2, Germany

    Eckhard Thiel, Stephan Thierfelder

Bibliographic Information

  • Book Title: Leukemia

  • Book Subtitle: Recent Developments in Diagnosis and Therapy

  • Editors: Eckhard Thiel, Stephan Thierfelder

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-642-82249-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1984

  • Softcover ISBN: 978-3-642-82251-3Published: 22 December 2011

  • eBook ISBN: 978-3-642-82249-0Published: 06 December 2012

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: X, 308

  • Topics: Hematology, Oncology

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