The Theory of Tracer Experiments with 131I-Labelled Plasma Proteins

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, , Citation Christine M E Matthews 1957 Phys. Med. Biol. 2 36 DOI 10.1088/0031-9155/2/1/305

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1 The National Institute for Medical Research, The Ridgeway, Mill Hill, London, N.W.7

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0031-9155/2/1/36

Abstract

Using the tracer theory of Rescigno, adapted for an open mammillary system, a method is given of finding (1) metabolic rate, (2) ratios of masses of protein in extravascular compartments to mass of protein in intravascular compartment, (3) capillary permeabilities, when 131I-labelled protein is injected into the blood stream of animals. Examples are given for human, rabbit and rat.

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10.1088/0031-9155/2/1/305