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Erschienen in: Der Anaesthesist 4/2005

01.04.2005 | Leitthema

Perioperative Strategien zur Regulierung des Sympathikotonus

verfasst von: J. Wacker, T. Pasch, M. C. Schaub, M. Zaugg

Erschienen in: Die Anaesthesiologie | Ausgabe 4/2005

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Zusammenfassung

Obwohl für verschiedene therapeutische Konzepte zur Verminderung der kardialen perioperativen Morbidität und Mortalität zunehmend Evidenz vorliegt, bleibt die tatsächliche Umsetzung solcher Konzepte im klinischen Alltag oft aus. Zwar ist einem großen Teil der klinisch tätigen Ärzte die wachsende Literatur bekannt; dieses Wissen wird aber nur in einem Teil der Fälle angewendet, selbst wenn allgemein akzeptierte Indikationen bestehen. Die vorliegende Übersichtsarbeit hat deshalb zum Ziel, die Gründe für die mangelnde Umsetzung aufzuzeigen und nochmals die wesentlichen Grundlagen sowie die klinische Bedeutung einzelner Strategien einschließlich des α2-Agonismus, der β-adrenergen Blockade und der Regionalanästhesien zusammenzufassen. Dies insbesondere im Hinblick auf die klinische Anwendung dieser Konzepte in einem allgemeinanästhesiologischen Umfeld. Zudem wird ein Ausblick in die auf „gene profiling“ basierende individualisierte Pharmakotherapie der perioperativen Medizin von morgen gegeben.
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Metadaten
Titel
Perioperative Strategien zur Regulierung des Sympathikotonus
verfasst von
J. Wacker
T. Pasch
M. C. Schaub
M. Zaugg
Publikationsdatum
01.04.2005
Verlag
Springer-Verlag
Erschienen in
Die Anaesthesiologie / Ausgabe 4/2005
Print ISSN: 2731-6858
Elektronische ISSN: 2731-6866
DOI
https://doi.org/10.1007/s00101-005-0826-1

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