Skip to main content

2018 | OriginalPaper | Buchkapitel

13. Stoffwechselprinzipien der Ernährung

verfasst von : Petra Stuparits, Erich Roth, Karl-Heinz Wagner

Erschienen in: Molekulare Sport- und Leistungsphysiologie

Verlag: Springer Vienna

Zusammenfassung

Die Ernährung des Sportlers stellt neben dem Training eine wichtige Grundlage für die sportliche Leistungsfähigkeit dar. Dabei geht es nicht nur um eine ausreichende Versorgung des Sportlers hinsichtlich des Energie- bzw. Makro- und Mikronährstoffbedarfs, um das Funktionieren der normalen physiologischen Vorgänge zu gewährleisten, sondern vielmehr darum, Stoffwechselwege auf zellulärer Ebene und somit die Anpassungsmechanismen an verschiedene Trainingsreize zu optimieren. Bei ihrem Abbau liefern die Makronährstoffe dem Organismus zum einen Verbrennungsenergie und zum anderen Bausteine, welche dann entweder zur Energiegewinnung weiter zerlegt (kataboler Stoffwechsel) oder zum Aufbau neuer Moleküle (anaboler Stoffwechsel) verwendet werden können. Bezüglich der Sporternährung können Nahrungsergänzungsmittel unter bestimmten Umständen dazu beitragen, die Deckung des Nährstoffbedarfs zu erleichtern bzw. optimieren.
Literatur
[1]
Zurück zum Zitat Biesalksi HK, Bischoff SC, Puchstein C (2010) Ernährungsmedizin. 4. Auflage edn. Thieme, Stuttgart Biesalksi HK, Bischoff SC, Puchstein C (2010) Ernährungsmedizin. 4. Auflage edn. Thieme, Stuttgart
[2]
Zurück zum Zitat Frayn KN (2010) Metabolic Regulation: A Human Perspective. Wiley-Blackwell, Chichester Frayn KN (2010) Metabolic Regulation: A Human Perspective. Wiley-Blackwell, Chichester
[3]
Zurück zum Zitat Nieman DC, Pedersen BK (2000) Nutrition and Exercise Immunology. CRC Press, Boca Raton Nieman DC, Pedersen BK (2000) Nutrition and Exercise Immunology. CRC Press, Boca Raton
[4]
Zurück zum Zitat Raschka C, Ruf S (2012) Sport und Ernährung. Wissenschaftlich basierte Empfehlunen und Ernährugnspläne für die Praxis, vol 1. Aufl. Stuttgart Raschka C, Ruf S (2012) Sport und Ernährung. Wissenschaftlich basierte Empfehlunen und Ernährugnspläne für die Praxis, vol 1. Aufl. Stuttgart
[5]
Zurück zum Zitat Schlieper CA (2010) Grundfragen der Ernährung. Handwerk und Technik, Hamburg Schlieper CA (2010) Grundfragen der Ernährung. Handwerk und Technik, Hamburg
[6]
Zurück zum Zitat Widhalm K (ed) (2009) Ernährungsmedizin. Die Nährstoffe bei körperlicher Aktivität. Verl.-Haus der Ärzte Wien Widhalm K (ed) (2009) Ernährungsmedizin. Die Nährstoffe bei körperlicher Aktivität. Verl.-Haus der Ärzte Wien
[7]
Zurück zum Zitat Brody T (1999) Nutritional biochemistry Academic Press, San Diego, Californien Brody T (1999) Nutritional biochemistry Academic Press, San Diego, Californien
[9]
Zurück zum Zitat Sawka MN, Burke LM, Eichner ER, Maughan RJ, Montain SJ, Stachenfeld NS (2007) American College of Sports Medicine position stand. Exercise and fluid replacement. Med Sci Sports Exerc 39 (2):377–390. doi:10.1249/mss.0b013e31802ca597. 00005768-200702000-00022 [pii]PubMedCrossRef Sawka MN, Burke LM, Eichner ER, Maughan RJ, Montain SJ, Stachenfeld NS (2007) American College of Sports Medicine position stand. Exercise and fluid replacement. Med Sci Sports Exerc 39 (2):377–390. doi:10.​1249/​mss.​0b013e31802ca597​. 00005768-200702000-00022 [pii]PubMedCrossRef
[10]
Zurück zum Zitat Hipp A, Nieß A (2008) Vitamine im Sport – Nutzen oder Risiko? Deutsche Zeitschrift für Sportmdeizin 59 (3): 2 Hipp A, Nieß A (2008) Vitamine im Sport – Nutzen oder Risiko? Deutsche Zeitschrift für Sportmdeizin 59 (3): 2
[11]
Zurück zum Zitat Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C (2007) Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA 297 (8):842–857. doi:297/8/842 [pii]. 10.1001/jama.297.8.842PubMedCrossRef Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C (2007) Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA 297 (8):842–857. doi:297/8/842 [pii]. 10.1001/jama.297.8.842PubMedCrossRef
[12]
Zurück zum Zitat Roth E (2007) Immune and cell modulation by amino acids. Clin Nutr 26 (5):535–544. doi:S0261-5614(07)00094-5 [pii]. 10.1016/j.clnu.2007.05.007PubMedCrossRef Roth E (2007) Immune and cell modulation by amino acids. Clin Nutr 26 (5):535–544. doi:S0261-5614(07)00094-5 [pii]. 10.1016/j.clnu.2007.05.007PubMedCrossRef
[13]
Zurück zum Zitat Roth E (2008) Nonnutritive effects of glutamine. J Nutr 138 (10):2025S–2031S. doi:138/10S-I/2025S [pii]PubMed Roth E (2008) Nonnutritive effects of glutamine. J Nutr 138 (10):2025S–2031S. doi:138/10S-I/2025S [pii]PubMed
[15]
Zurück zum Zitat Vettor R, Milan G, Franzin C, Sanna M, De Coppi P, Rizzuto R, Federspil G (2009) The origin of intermuscular adipose tissue and its pathophysiological implications. Am J Physiol Endocrinol Metab 297 (5):E987–998. doi:10.1152/ajpendo.00229.2009. 00229.2009 [pii]PubMedCrossRef Vettor R, Milan G, Franzin C, Sanna M, De Coppi P, Rizzuto R, Federspil G (2009) The origin of intermuscular adipose tissue and its pathophysiological implications. Am J Physiol Endocrinol Metab 297 (5):E987–998. doi:10.​1152/​ajpendo.​00229.​2009.​ 00229.2009 [pii]PubMedCrossRef
[16]
Zurück zum Zitat Coffey VG, Hawley JA (2007) The molecular bases of training adaptation. Sports Med 37 (9):737–763. doi:3791 [pii]PubMedCrossRef Coffey VG, Hawley JA (2007) The molecular bases of training adaptation. Sports Med 37 (9):737–763. doi:3791 [pii]PubMedCrossRef
[18]
Zurück zum Zitat Hawley JA (2002) Adaptations of skeletal muscle to prolonged, intense endurance training. Clin Exp Pharmacol Physiol 29 (3):218–222PubMedCrossRef Hawley JA (2002) Adaptations of skeletal muscle to prolonged, intense endurance training. Clin Exp Pharmacol Physiol 29 (3):218–222PubMedCrossRef
[20]
Zurück zum Zitat Cameron-Smith D, Burke LM, Angus DJ, Tunstall RJ, Cox GR, Bonen A et al. (2003) A short-term, high-fat diet up-regulates lipid metabolism and gene expression in human skeletal muscle. Am J Clin Nutr 77 (2):313–318PubMed Cameron-Smith D, Burke LM, Angus DJ, Tunstall RJ, Cox GR, Bonen A et al. (2003) A short-term, high-fat diet up-regulates lipid metabolism and gene expression in human skeletal muscle. Am J Clin Nutr 77 (2):313–318PubMed
[22]
Zurück zum Zitat Zderic TW, Davidson CJ, Schenk S, Byerley LO, Coyle EF (2004) High-fat diet elevates resting intramuscular triglyceride concentration and whole body lipolysis during exercise. Am J Physiol Endocrinol Metab 286 (2):E217–225. doi:10.1152/ajpendo.00159.2003. 00159.2003 [pii]PubMedCrossRef Zderic TW, Davidson CJ, Schenk S, Byerley LO, Coyle EF (2004) High-fat diet elevates resting intramuscular triglyceride concentration and whole body lipolysis during exercise. Am J Physiol Endocrinol Metab 286 (2):E217–225. doi:10.​1152/​ajpendo.​00159.​2003.​ 00159.2003 [pii]PubMedCrossRef
[23]
Zurück zum Zitat Coyle EF, Jeukendrup AE, Oseto MC, Hodgkinson BJ, Zderic TW (2001) Low-fat diet alters intramuscular substrates and reduces lipolysis and fat oxidation during exercise. Am J Physiol Endocrinol Metab 280 (3):E391–398PubMed Coyle EF, Jeukendrup AE, Oseto MC, Hodgkinson BJ, Zderic TW (2001) Low-fat diet alters intramuscular substrates and reduces lipolysis and fat oxidation during exercise. Am J Physiol Endocrinol Metab 280 (3):E391–398PubMed
[24]
Zurück zum Zitat Horowitz JF, Mora-Rodriguez R, Byerley LO, Coyle EF (1997) Lipolytic suppression following carbohydrate ingestion limits fat oxidation during exercise. Am J Physiol 273 (4 Pt 1):E768–775PubMed Horowitz JF, Mora-Rodriguez R, Byerley LO, Coyle EF (1997) Lipolytic suppression following carbohydrate ingestion limits fat oxidation during exercise. Am J Physiol 273 (4 Pt 1):E768–775PubMed
[25]
Zurück zum Zitat Horowitz JF, Mora-Rodriguez R, Byerley LO, Coyle EF (1999) Substrate metabolism when subjects are fed carbohydrate during exercise. Am J Physiol 276 (5 Pt 1):E828–835PubMed Horowitz JF, Mora-Rodriguez R, Byerley LO, Coyle EF (1999) Substrate metabolism when subjects are fed carbohydrate during exercise. Am J Physiol 276 (5 Pt 1):E828–835PubMed
[26]
Zurück zum Zitat Freyssenet D (2007) Energy sensing and regulation of gene expression in skeletal muscle. J Appl Physiol 102 (2):529–540. doi:01126.2005 [pii]. 10.1152/japplphysiol.01126.2005PubMedCrossRef Freyssenet D (2007) Energy sensing and regulation of gene expression in skeletal muscle. J Appl Physiol 102 (2):529–540. doi:01126.2005 [pii]. 10.1152/japplphysiol.01126.2005PubMedCrossRef
[27]
Zurück zum Zitat Coggan AR, Kohrt WM, Spina RJ, Bier DM, Holloszy JO (1990) Endurance training decreases plasma glucose turnover and oxidation during moderate-intensity exercise in men. J Appl Physiol 68 (3):990–996PubMed Coggan AR, Kohrt WM, Spina RJ, Bier DM, Holloszy JO (1990) Endurance training decreases plasma glucose turnover and oxidation during moderate-intensity exercise in men. J Appl Physiol 68 (3):990–996PubMed
[28]
Zurück zum Zitat Churchley EG, Coffey VG, Pedersen DJ, Shield A, Carey KA, Cameron-Smith D, Hawley JA (2007) Influence of preexercise muscle glycogen content on transcriptional activity of metabolic and myogenic genes in well-trained humans. J Appl Physiol 102 (4):1604–1611. doi:01260.2006 [pii]. 10.1152/japplphysiol.01260.2006PubMedCrossRef Churchley EG, Coffey VG, Pedersen DJ, Shield A, Carey KA, Cameron-Smith D, Hawley JA (2007) Influence of preexercise muscle glycogen content on transcriptional activity of metabolic and myogenic genes in well-trained humans. J Appl Physiol 102 (4):1604–1611. doi:01260.2006 [pii]. 10.1152/japplphysiol.01260.2006PubMedCrossRef
[29]
Zurück zum Zitat Creer A, Gallagher P, Slivka D, Jemiolo B, Fink W, Trappe S (2005) Influence of muscle glycogen availability on ERK1/2 and Akt signaling after resistance exercise in human skeletal muscle. J Appl Physiol 99 (3):950–956. doi:00110.2005 [pii]. 10.1152/japplphysiol.00110.2005PubMedCrossRef Creer A, Gallagher P, Slivka D, Jemiolo B, Fink W, Trappe S (2005) Influence of muscle glycogen availability on ERK1/2 and Akt signaling after resistance exercise in human skeletal muscle. J Appl Physiol 99 (3):950–956. doi:00110.2005 [pii]. 10.1152/japplphysiol.00110.2005PubMedCrossRef
[30]
Zurück zum Zitat Bergstrom J, Hultman E (1966) The effect of exercise on muscle glycogen and electrolytes in normals. Scand J Clin Lab Invest 18 (1):16–20PubMedCrossRef Bergstrom J, Hultman E (1966) The effect of exercise on muscle glycogen and electrolytes in normals. Scand J Clin Lab Invest 18 (1):16–20PubMedCrossRef
[33]
Zurück zum Zitat Kreider RB, Wilborn CD, Taylor L, Campbell B, Almada AL, Collins R et al. (2010) ISSN exercise & sport nutrition review: research & recommendations. J Int Soc Sports Nutr 7:7. doi:10.1186/1550-2783-7-7. 1550-2783-7-7 [pii] Kreider RB, Wilborn CD, Taylor L, Campbell B, Almada AL, Collins R et al. (2010) ISSN exercise & sport nutrition review: research & recommendations. J Int Soc Sports Nutr 7:7. doi:10.​1186/​1550-2783-7-7. 1550-2783-7-7 [pii]
[34]
[36]
[38]
[39]
Zurück zum Zitat Yeo WK, Lessard SJ, Chen ZP, Garnham AP, Burke LM, Rivas DA et al. (2008) Fat adaptation followed by carbohydrate restoration increases AMPK activity in skeletal muscle from trained humans. J Appl Physiol 105 (5):1519–1526. doi:10.1152/japplphysiol.90540.2008. 90540.2008 [pii]PubMedCrossRef Yeo WK, Lessard SJ, Chen ZP, Garnham AP, Burke LM, Rivas DA et al. (2008) Fat adaptation followed by carbohydrate restoration increases AMPK activity in skeletal muscle from trained humans. J Appl Physiol 105 (5):1519–1526. doi:10.​1152/​japplphysiol.​90540.​2008. 90540.2008 [pii]PubMedCrossRef
[44]
Zurück zum Zitat Bendayan M, Londono I, Kemp BE, Hardie GD, Ruderman N, Prentki M (2009) Association of AMP-activated protein kinase subunits with glycogen particles as revealed in situ by immunoelectron microscopy. J Histochem Cytochem 57 (10):963–971. doi:10.1369/jhc.2009.954016. jhc.2009.954016 [pii]PubMedPubMedCentralCrossRef Bendayan M, Londono I, Kemp BE, Hardie GD, Ruderman N, Prentki M (2009) Association of AMP-activated protein kinase subunits with glycogen particles as revealed in situ by immunoelectron microscopy. J Histochem Cytochem 57 (10):963–971. doi:10.​1369/​jhc.​2009.​954016. jhc.2009.954016 [pii]PubMedPubMedCentralCrossRef
[45]
Zurück zum Zitat Hudson ER, Pan DA, James J, Lucocq JM, Hawley SA, Green KA et al. (2003) A novel domain in AMP-activated protein kinase causes glycogen storage bodies similar to those seen in hereditary cardiac arrhythmias. Curr Biol 13 (10):861–866. doi:S0960982203002495 [pii]PubMedCrossRef Hudson ER, Pan DA, James J, Lucocq JM, Hawley SA, Green KA et al. (2003) A novel domain in AMP-activated protein kinase causes glycogen storage bodies similar to those seen in hereditary cardiac arrhythmias. Curr Biol 13 (10):861–866. doi:S0960982203002495 [pii]PubMedCrossRef
[46]
Zurück zum Zitat Polekhina G, Gupta A, Michell BJ, van Denderen B, Murthy S, Feil SC et al. (2003) AMPK beta subunit targets metabolic stress sensing to glycogen. Curr Biol 13 (10):867–871. doi:S0960982203002926 [pii]PubMedCrossRef Polekhina G, Gupta A, Michell BJ, van Denderen B, Murthy S, Feil SC et al. (2003) AMPK beta subunit targets metabolic stress sensing to glycogen. Curr Biol 13 (10):867–871. doi:S0960982203002926 [pii]PubMedCrossRef
[47]
[48]
Zurück zum Zitat Wojtaszewski JF, MacDonald C, Nielsen JN, Hellsten Y, Hardie DG, Kemp BE et al. (2003) Regulation of 5'AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle. Am J Physiol Endocrinol Metab 284 (4):E813–822. doi:10.1152/ajpendo.00436.2002. 00436.2002 [pii]PubMedCrossRef Wojtaszewski JF, MacDonald C, Nielsen JN, Hellsten Y, Hardie DG, Kemp BE et al. (2003) Regulation of 5'AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle. Am J Physiol Endocrinol Metab 284 (4):E813–822. doi:10.​1152/​ajpendo.​00436.​2002. 00436.2002 [pii]PubMedCrossRef
[49]
Zurück zum Zitat Yeo WK, McGee SL, Carey AL, Paton CD, Garnham AP, Hargreaves M, Hawley JA (2010) Acute signalling responses to intense endurance training commenced with low or normal muscle glycogen. Exp Physiol 95 (2):351–358. doi:10.1113/expphysiol.2009.049353. expphysiol.2009.049353 [pii]PubMedCrossRef Yeo WK, McGee SL, Carey AL, Paton CD, Garnham AP, Hargreaves M, Hawley JA (2010) Acute signalling responses to intense endurance training commenced with low or normal muscle glycogen. Exp Physiol 95 (2):351–358. doi:10.​1113/​expphysiol.​2009.​049353. expphysiol.2009.049353 [pii]PubMedCrossRef
[50]
Zurück zum Zitat Cochran AJ, Little JP, Tarnopolsky MA, Gibala MJ (2010) Carbohydrate feeding during recovery alters the skeletal muscle metabolic response to repeated sessions of high-intensity interval exercise in humans. J Appl Physiol 108 (3):628–636. doi:10.1152/japplphysiol.00659.2009. 00659.2009 [pii]PubMedCrossRef Cochran AJ, Little JP, Tarnopolsky MA, Gibala MJ (2010) Carbohydrate feeding during recovery alters the skeletal muscle metabolic response to repeated sessions of high-intensity interval exercise in humans. J Appl Physiol 108 (3):628–636. doi:10.​1152/​japplphysiol.​00659.​2009. 00659.2009 [pii]PubMedCrossRef
[51]
Zurück zum Zitat Bergman BC, Butterfield GE, Wolfel EE, Lopaschuk GD, Casazza GA, Horning MA, Brooks GA (1999) Muscle net glucose uptake and glucose kinetics after endurance training in men. Am J Physiol 277 (1 Pt 1):E81–92PubMed Bergman BC, Butterfield GE, Wolfel EE, Lopaschuk GD, Casazza GA, Horning MA, Brooks GA (1999) Muscle net glucose uptake and glucose kinetics after endurance training in men. Am J Physiol 277 (1 Pt 1):E81–92PubMed
[52]
Zurück zum Zitat Friedlander AL, Casazza GA, Horning MA, Huie MJ, Brooks GA (1997) Training-induced alterations of glucose flux in men. J Appl Physiol 82 (4):1360–1369PubMed Friedlander AL, Casazza GA, Horning MA, Huie MJ, Brooks GA (1997) Training-induced alterations of glucose flux in men. J Appl Physiol 82 (4):1360–1369PubMed
[53]
Zurück zum Zitat Friedlander AL, Casazza GA, Horning MA, Huie MJ, Piacentini MF, Trimmer JK, Brooks GA (1998) Training-induced alterations of carbohydrate metabolism in women: women respond differently from men. J Appl Physiol 85 (3):1175–1186PubMed Friedlander AL, Casazza GA, Horning MA, Huie MJ, Piacentini MF, Trimmer JK, Brooks GA (1998) Training-induced alterations of carbohydrate metabolism in women: women respond differently from men. J Appl Physiol 85 (3):1175–1186PubMed
[54]
Zurück zum Zitat Richter EA, Jensen P, Kiens B, Kristiansen S (1998) Sarcolemmal glucose transport and GLUT-4 translocation during exercise are diminished by endurance training. Am J Physiol 274 (1 Pt 1):E89–95PubMed Richter EA, Jensen P, Kiens B, Kristiansen S (1998) Sarcolemmal glucose transport and GLUT-4 translocation during exercise are diminished by endurance training. Am J Physiol 274 (1 Pt 1):E89–95PubMed
[55]
Zurück zum Zitat Kristiansen S, Gade J, Wojtaszewski JF, Kiens B, Richter EA (2000) Glucose uptake is increased in trained vs. untrained muscle during heavy exercise. J Appl Physiol 89 (3):1151–1158PubMed Kristiansen S, Gade J, Wojtaszewski JF, Kiens B, Richter EA (2000) Glucose uptake is increased in trained vs. untrained muscle during heavy exercise. J Appl Physiol 89 (3):1151–1158PubMed
[56]
Zurück zum Zitat Stepto NK, Carey AL, Staudacher HM, Cummings NK, Burke LM, Hawley JA (2002) Effect of short-term fat adaptation on high-intensity training. Med Sci Sports Exerc 34 (3):449–455PubMedCrossRef Stepto NK, Carey AL, Staudacher HM, Cummings NK, Burke LM, Hawley JA (2002) Effect of short-term fat adaptation on high-intensity training. Med Sci Sports Exerc 34 (3):449–455PubMedCrossRef
[57]
Zurück zum Zitat Hawley JA, Hopkins WG (1995) Aerobic glycolytic and aerobic lipolytic power systems. A new paradigm with implications for endurance and ultraendurance events. Sports Med 19 (4):240–250PubMedCrossRef Hawley JA, Hopkins WG (1995) Aerobic glycolytic and aerobic lipolytic power systems. A new paradigm with implications for endurance and ultraendurance events. Sports Med 19 (4):240–250PubMedCrossRef
[58]
Zurück zum Zitat Lambert EV, Speechly DP, Dennis SC, Noakes TD (1994) Enhanced endurance in trained cyclists during moderate intensity exercise following 2 weeks adaptation to a high fat diet. Eur J Appl Physiol Occup Physiol 69 (4):287–293PubMedCrossRef Lambert EV, Speechly DP, Dennis SC, Noakes TD (1994) Enhanced endurance in trained cyclists during moderate intensity exercise following 2 weeks adaptation to a high fat diet. Eur J Appl Physiol Occup Physiol 69 (4):287–293PubMedCrossRef
[59]
Zurück zum Zitat Muoio DM, Leddy JJ, Horvath PJ, Awad AB, Pendergast DR (1994) Effect of dietary fat on metabolic adjustments to maximal VO2 and endurance in runners. Med Sci Sports Exerc 26 (1):81–88PubMedCrossRef Muoio DM, Leddy JJ, Horvath PJ, Awad AB, Pendergast DR (1994) Effect of dietary fat on metabolic adjustments to maximal VO2 and endurance in runners. Med Sci Sports Exerc 26 (1):81–88PubMedCrossRef
[60]
Zurück zum Zitat Venkatraman JT, Feng X, Pendergast D (2001) Effects of dietary fat and endurance exercise on plasma cortisol, prostaglandin E2, interferon-gamma and lipid peroxides in runners. J Am Coll Nutr 20 (5):529–536PubMedCrossRef Venkatraman JT, Feng X, Pendergast D (2001) Effects of dietary fat and endurance exercise on plasma cortisol, prostaglandin E2, interferon-gamma and lipid peroxides in runners. J Am Coll Nutr 20 (5):529–536PubMedCrossRef
[61]
Zurück zum Zitat Phinney SD, Bistrian BR, Evans WJ, Gervino E, Blackburn GL (1983) The human metabolic response to chronic ketosis without caloric restriction: preservation of submaximal exercise capability with reduced carbohydrate oxidation. Metabolism 32 (8):769–776. doi:0026-0495(83)90106-3 [pii]PubMedCrossRef Phinney SD, Bistrian BR, Evans WJ, Gervino E, Blackburn GL (1983) The human metabolic response to chronic ketosis without caloric restriction: preservation of submaximal exercise capability with reduced carbohydrate oxidation. Metabolism 32 (8):769–776. doi:0026-0495(83)90106-3 [pii]PubMedCrossRef
[62]
Zurück zum Zitat Burke LM, Angus DJ, Cox GR, Cummings NK, Febbraio MA, Gawthorn K et al. (2000) Effect of fat adaptation and carbohydrate restoration on metabolism and performance during prolonged cycling. J Appl Physiol 89 (6):2413–2421PubMed Burke LM, Angus DJ, Cox GR, Cummings NK, Febbraio MA, Gawthorn K et al. (2000) Effect of fat adaptation and carbohydrate restoration on metabolism and performance during prolonged cycling. J Appl Physiol 89 (6):2413–2421PubMed
[63]
Zurück zum Zitat Burke LM, Hawley JA, Angus DJ, Cox GR, Clark SA, Cummings NK et al. (2002) Adaptations to short-term high-fat diet persist during exercise despite high carbohydrate availability. Med Sci Sports Exerc 34 (1):83–91PubMedCrossRef Burke LM, Hawley JA, Angus DJ, Cox GR, Clark SA, Cummings NK et al. (2002) Adaptations to short-term high-fat diet persist during exercise despite high carbohydrate availability. Med Sci Sports Exerc 34 (1):83–91PubMedCrossRef
[64]
Zurück zum Zitat Carey AL, Staudacher HM, Cummings NK, Stepto NK, Nikolopoulos V, Burke LM, Hawley JA (2001) Effects of fat adaptation and carbohydrate restoration on prolonged endurance exercise. J Appl Physiol 91 (1):115–122PubMed Carey AL, Staudacher HM, Cummings NK, Stepto NK, Nikolopoulos V, Burke LM, Hawley JA (2001) Effects of fat adaptation and carbohydrate restoration on prolonged endurance exercise. J Appl Physiol 91 (1):115–122PubMed
[65]
Zurück zum Zitat Stellingwerff T, Spriet LL, Watt MJ, Kimber NE, Hargreaves M, Hawley JA, Burke LM (2006) Decreased PDH activation and glycogenolysis during exercise following fat adaptation with carbohydrate restoration. Am J Physiol Endocrinol Metab 290 (2):E380–388. doi:00268.2005 [pii]. 10.1152/ajpendo.00268.2005PubMedCrossRef Stellingwerff T, Spriet LL, Watt MJ, Kimber NE, Hargreaves M, Hawley JA, Burke LM (2006) Decreased PDH activation and glycogenolysis during exercise following fat adaptation with carbohydrate restoration. Am J Physiol Endocrinol Metab 290 (2):E380–388. doi:00268.2005 [pii]. 10.1152/ajpendo.00268.2005PubMedCrossRef
[66]
Zurück zum Zitat Lambert EV, Goedecke JH, Zyle C, Murphy K, Hawley JA, Dennis SC, Noakes TD (2001) High-fat diet versus habitual diet prior to carbohydrate loading: effects of exercise metabolism and cycling performance. Int J Sport Nutr Exerc Metab 11 (2):209–225PubMedCrossRef Lambert EV, Goedecke JH, Zyle C, Murphy K, Hawley JA, Dennis SC, Noakes TD (2001) High-fat diet versus habitual diet prior to carbohydrate loading: effects of exercise metabolism and cycling performance. Int J Sport Nutr Exerc Metab 11 (2):209–225PubMedCrossRef
[67]
Zurück zum Zitat Rowlands DS, Hopkins WG (2002) Effects of high-fat and high-carbohydrate diets on metabolism and performance in cycling. Metabolism 51 (6):678–690. doi:S0026049502987007 [pii]PubMedCrossRef Rowlands DS, Hopkins WG (2002) Effects of high-fat and high-carbohydrate diets on metabolism and performance in cycling. Metabolism 51 (6):678–690. doi:S0026049502987007 [pii]PubMedCrossRef
[68]
Zurück zum Zitat Havemann L, West SJ, Goedecke JH, Macdonald IA, St Clair Gibson A, Noakes TD, Lambert EV (2006) Fat adaptation followed by carbohydrate loading compromises high-intensity sprint performance. J Appl Physiol 100 (1):194–202. doi:00813.2005 [pii]. 10.1152/japplphysiol.00813.2005PubMedCrossRef Havemann L, West SJ, Goedecke JH, Macdonald IA, St Clair Gibson A, Noakes TD, Lambert EV (2006) Fat adaptation followed by carbohydrate loading compromises high-intensity sprint performance. J Appl Physiol 100 (1):194–202. doi:00813.2005 [pii]. 10.1152/japplphysiol.00813.2005PubMedCrossRef
[69]
Zurück zum Zitat Yeo WK, Carey AL, Burke L, Spriet LL, Hawley JA (2011) Fat adaptation in well-trained athletes: effects on cell metabolism. Appl Physiol Nutr Metab 36 (1):12–22. doi:10.1139/H10-089. h10-089 [pii]PubMedCrossRef Yeo WK, Carey AL, Burke L, Spriet LL, Hawley JA (2011) Fat adaptation in well-trained athletes: effects on cell metabolism. Appl Physiol Nutr Metab 36 (1):12–22. doi:10.​1139/​H10-089. h10-089 [pii]PubMedCrossRef
[70]
Zurück zum Zitat Braissant O, Foufelle F, Scotto C, Dauca M, Wahli W (1996) Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology 137 (1):354–366PubMedCrossRef Braissant O, Foufelle F, Scotto C, Dauca M, Wahli W (1996) Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology 137 (1):354–366PubMedCrossRef
[71]
Zurück zum Zitat Muoio DM, MacLean PS, Lang DB, Li S, Houmard JA, Way JM et al. (2002) Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta. J Biol Chem 277 (29):26089–26097. doi:10.1074/jbc.M203997200. M203997200 [pii]PubMedCrossRef Muoio DM, MacLean PS, Lang DB, Li S, Houmard JA, Way JM et al. (2002) Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta. J Biol Chem 277 (29):26089–26097. doi:10.​1074/​jbc.​M203997200. M203997200 [pii]PubMedCrossRef
[72]
Zurück zum Zitat de Lange P, Ragni M, Silvestri E, Moreno M, Schiavo L, Lombardi A et al. (2004) Combined cDNA array/RT-PCR analysis of gene expression profile in rat gastrocnemius muscle: relation to its adaptive function in energy metabolism during fasting. FASEB J 18 (2):350–352. doi:10.1096/fj.03-0342fje. 03-0342fje [pii]PubMed de Lange P, Ragni M, Silvestri E, Moreno M, Schiavo L, Lombardi A et al. (2004) Combined cDNA array/RT-PCR analysis of gene expression profile in rat gastrocnemius muscle: relation to its adaptive function in energy metabolism during fasting. FASEB J 18 (2):350–352. doi:10.​1096/​fj.​03-0342fje. 03-0342fje [pii]PubMed
[74]
Zurück zum Zitat Watt MJ, Southgate RJ, Holmes AG, Febbraio MA (2004) Suppression of plasma free fatty acids upregulates peroxisome proliferator-activated receptor (PPAR) alpha and delta and PPAR coactivator 1alpha in human skeletal muscle, but not lipid regulatory genes. J Mol Endocrinol 33 (2):533–544. doi:33/2/533 [pii]. 10.1677/jme.1.01499PubMedCrossRef Watt MJ, Southgate RJ, Holmes AG, Febbraio MA (2004) Suppression of plasma free fatty acids upregulates peroxisome proliferator-activated receptor (PPAR) alpha and delta and PPAR coactivator 1alpha in human skeletal muscle, but not lipid regulatory genes. J Mol Endocrinol 33 (2):533–544. doi:33/2/533 [pii]. 10.1677/jme.1.01499PubMedCrossRef
[75]
Zurück zum Zitat Mahoney DJ, Parise G, Melov S, Safdar A, Tarnopolsky MA (2005) Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise. FASEB J 19 (11):1498–1500. doi:04-3149fje [pii]. 10.1096/fj.04-3149fjePubMed Mahoney DJ, Parise G, Melov S, Safdar A, Tarnopolsky MA (2005) Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise. FASEB J 19 (11):1498–1500. doi:04-3149fje [pii]. 10.1096/fj.04-3149fjePubMed
[76]
Zurück zum Zitat Russell AP, Hesselink MK, Lo SK, Schrauwen P (2005) Regulation of metabolic transcriptional co-activators and transcription factors with acute exercise. FASEB J 19 (8):986–988. doi:04-3168fje [pii]. 10.1096/fj.04-3168fjePubMed Russell AP, Hesselink MK, Lo SK, Schrauwen P (2005) Regulation of metabolic transcriptional co-activators and transcription factors with acute exercise. FASEB J 19 (8):986–988. doi:04-3168fje [pii]. 10.1096/fj.04-3168fjePubMed
[77]
Zurück zum Zitat Russell AP, Feilchenfeldt J, Schreiber S, Praz M, Crettenand A, Gobelet C et al. (2003) Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor-gamma coactivator-1 and peroxisome proliferator-activated receptor-alpha in skeletal muscle. Diabetes 52 (12):2874–2881PubMedCrossRef Russell AP, Feilchenfeldt J, Schreiber S, Praz M, Crettenand A, Gobelet C et al. (2003) Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor-gamma coactivator-1 and peroxisome proliferator-activated receptor-alpha in skeletal muscle. Diabetes 52 (12):2874–2881PubMedCrossRef
[78]
Zurück zum Zitat Fritz T, Kramer DK, Karlsson HK, Galuska D, Engfeldt P, Zierath JR, Krook A (2006) Low-intensity exercise increases skeletal muscle protein expression of PPARdelta and UCP3 in type 2 diabetic patients. Diabetes Metab Res Rev 22 (6):492–498. doi:10.1002/dmrr.656 PubMedCrossRef Fritz T, Kramer DK, Karlsson HK, Galuska D, Engfeldt P, Zierath JR, Krook A (2006) Low-intensity exercise increases skeletal muscle protein expression of PPARdelta and UCP3 in type 2 diabetic patients. Diabetes Metab Res Rev 22 (6):492–498. doi:10.​1002/​dmrr.​656 PubMedCrossRef
[79]
Zurück zum Zitat de Lange P, Farina P, Moreno M, Ragni M, Lombardi A, Silvestri E et al. (2006) Sequential changes in the signal transduction responses of skeletal muscle following food deprivation. FASEB J 20 (14):2579–2581. doi:fj.06-6025fje [pii]. 10.1096/fj.06-6025fjePubMedCrossRef de Lange P, Farina P, Moreno M, Ragni M, Lombardi A, Silvestri E et al. (2006) Sequential changes in the signal transduction responses of skeletal muscle following food deprivation. FASEB J 20 (14):2579–2581. doi:fj.06-6025fje [pii]. 10.1096/fj.06-6025fjePubMedCrossRef
[80]
Zurück zum Zitat Tsintzas K, Jewell K, Kamran M, Laithwaite D, Boonsong T, Littlewood J et al. (2006) Differential regulation of metabolic genes in skeletal muscle during starvation and refeeding in humans. J Physiol 575 (Pt 1): 291–303. doi:jphysiol.2006.109892 [pii]. 10.1113/jphysiol.2006.109892PubMedPubMedCentralCrossRef Tsintzas K, Jewell K, Kamran M, Laithwaite D, Boonsong T, Littlewood J et al. (2006) Differential regulation of metabolic genes in skeletal muscle during starvation and refeeding in humans. J Physiol 575 (Pt 1): 291–303. doi:jphysiol.2006.109892 [pii]. 10.1113/jphysiol.2006.109892PubMedPubMedCentralCrossRef
[81]
[82]
Zurück zum Zitat Nickerson JG, Alkhateeb H, Benton CR, Lally J, Nickerson J, Han XX et al. (2009) Greater transport efficiencies of the membrane fatty acid transporters FAT/CD36 and FATP4 compared with FABPpm and FATP1 and differential effects on fatty acid esterification and oxidation in rat skeletal muscle. J Biol Chem 284 (24):16522–16530. doi:10.1074/jbc.M109.004788. M109.004788 [pii]PubMedPubMedCentralCrossRef Nickerson JG, Alkhateeb H, Benton CR, Lally J, Nickerson J, Han XX et al. (2009) Greater transport efficiencies of the membrane fatty acid transporters FAT/CD36 and FATP4 compared with FABPpm and FATP1 and differential effects on fatty acid esterification and oxidation in rat skeletal muscle. J Biol Chem 284 (24):16522–16530. doi:10.​1074/​jbc.​M109.​004788. M109.004788 [pii]PubMedPubMedCentralCrossRef
[84]
Zurück zum Zitat Kiens B (2006) Skeletal muscle lipid metabolism in exercise and insulin resistance. Physiol Rev 86 (1):205–243. doi:86/1/205 [pii]. 10.1152/physrev.00023.2004PubMedCrossRef Kiens B (2006) Skeletal muscle lipid metabolism in exercise and insulin resistance. Physiol Rev 86 (1):205–243. doi:86/1/205 [pii]. 10.1152/physrev.00023.2004PubMedCrossRef
[88]
Zurück zum Zitat Kiens B, Essen-Gustavsson B, Gad P, Lithell H (1987) Lipoprotein lipase activity and intramuscular triglyceride stores after long-term high-fat and high-carbohydrate diets in physically trained men. Clin Physiol 7 (1):1–9PubMedCrossRef Kiens B, Essen-Gustavsson B, Gad P, Lithell H (1987) Lipoprotein lipase activity and intramuscular triglyceride stores after long-term high-fat and high-carbohydrate diets in physically trained men. Clin Physiol 7 (1):1–9PubMedCrossRef
[89]
Zurück zum Zitat Starling RD, Trappe TA, Parcell AC, Kerr CG, Fink WJ, Costill DL (1997) Effects of diet on muscle triglyceride and endurance performance. J Appl Physiol 82 (4):1185–1189PubMed Starling RD, Trappe TA, Parcell AC, Kerr CG, Fink WJ, Costill DL (1997) Effects of diet on muscle triglyceride and endurance performance. J Appl Physiol 82 (4):1185–1189PubMed
[90]
Zurück zum Zitat Peters SJ, St Amand TA, Howlett RA, Heigenhauser GJ, Spriet LL (1998) Human skeletal muscle pyruvate dehydrogenase kinase activity increases after a low-carbohydrate diet. Am J Physiol 275 (6 Pt 1):E980–986PubMed Peters SJ, St Amand TA, Howlett RA, Heigenhauser GJ, Spriet LL (1998) Human skeletal muscle pyruvate dehydrogenase kinase activity increases after a low-carbohydrate diet. Am J Physiol 275 (6 Pt 1):E980–986PubMed
[91]
Zurück zum Zitat Peters SJ, Harris RA, Wu P, Pehleman TL, Heigenhauser GJ, Spriet LL (2001) Human skeletal muscle PDH kinase activity and isoform expression during a 3-day high-fat/low-carbohydrate diet. Am J Physiol Endocrinol Metab 281 (6):E1151–1158PubMed Peters SJ, Harris RA, Wu P, Pehleman TL, Heigenhauser GJ, Spriet LL (2001) Human skeletal muscle PDH kinase activity and isoform expression during a 3-day high-fat/low-carbohydrate diet. Am J Physiol Endocrinol Metab 281 (6):E1151–1158PubMed
[92]
Zurück zum Zitat Putman CT, Spriet LL, Hultman E, Lindinger MI, Lands LC, McKelvie RS et al. (1993) Pyruvate dehydrogenase activity and acetyl group accumulation during exercise after different diets. Am J Physiol 265 (5 Pt 1):E752–760PubMed Putman CT, Spriet LL, Hultman E, Lindinger MI, Lands LC, McKelvie RS et al. (1993) Pyruvate dehydrogenase activity and acetyl group accumulation during exercise after different diets. Am J Physiol 265 (5 Pt 1):E752–760PubMed
[93]
Zurück zum Zitat Bigrigg JK, Heigenhauser GJ, Inglis JG, LeBlanc PJ, Peters SJ (2009) Carbohydrate refeeding after a high-fat diet rapidly reverses the adaptive increase in human skeletal muscle PDH kinase activity. Am J Physiol Regul Integr Comp Physiol 297 (3):R885–891. doi:10.1152/ajpregu.90604.2008. 90604.2008 [pii]PubMedCrossRef Bigrigg JK, Heigenhauser GJ, Inglis JG, LeBlanc PJ, Peters SJ (2009) Carbohydrate refeeding after a high-fat diet rapidly reverses the adaptive increase in human skeletal muscle PDH kinase activity. Am J Physiol Regul Integr Comp Physiol 297 (3):R885–891. doi:10.​1152/​ajpregu.​90604.​2008. 90604.2008 [pii]PubMedCrossRef
[97]
Zurück zum Zitat Norton LE, Layman DK (2006) Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise. J Nutr 136 (2):533S–537S. doi:136/2/533S [pii]PubMed Norton LE, Layman DK (2006) Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise. J Nutr 136 (2):533S–537S. doi:136/2/533S [pii]PubMed
[98]
Zurück zum Zitat Verhoeven S, Vanschoonbeek K, Verdijk LB, Koopman R, Wodzig WK, Dendale P, van Loon LJ (2009) Long-term leucine supplementation does not increase muscle mass or strength in healthy elderly men. Am J Clin Nutr 89 (5):1468–1475. doi:10.3945/ajcn.2008.26668. ajcn.2008.26668 [pii]PubMedCrossRef Verhoeven S, Vanschoonbeek K, Verdijk LB, Koopman R, Wodzig WK, Dendale P, van Loon LJ (2009) Long-term leucine supplementation does not increase muscle mass or strength in healthy elderly men. Am J Clin Nutr 89 (5):1468–1475. doi:10.​3945/​ajcn.​2008.​26668. ajcn.2008.26668 [pii]PubMedCrossRef
[100]
Zurück zum Zitat Tipton KD, Rasmussen BB, Miller SL, Wolf SE, Owens-Stovall SK, Petrini BE, Wolfe RR (2001) Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise. Am J Physiol Endocrinol Metab 281 (2):E197–206PubMed Tipton KD, Rasmussen BB, Miller SL, Wolf SE, Owens-Stovall SK, Petrini BE, Wolfe RR (2001) Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise. Am J Physiol Endocrinol Metab 281 (2):E197–206PubMed
[101]
Zurück zum Zitat Tipton KD, Elliott TA, Cree MG, Aarsland AA, Sanford AP, Wolfe RR (2007) Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise. Am J Physiol Endocrinol Metab 292 (1):E71–76. doi:00166.2006 [pii]. 10.1152/ajpendo.00166.2006PubMedCrossRef Tipton KD, Elliott TA, Cree MG, Aarsland AA, Sanford AP, Wolfe RR (2007) Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise. Am J Physiol Endocrinol Metab 292 (1):E71–76. doi:00166.2006 [pii]. 10.1152/ajpendo.00166.2006PubMedCrossRef
[102]
Zurück zum Zitat Fujita S, Dreyer HC, Drummond MJ, Glynn EL, Volpi E, Rasmussen BB (2009) Essential amino acid and carbohydrate ingestion before resistance exercise does not enhance postexercise muscle protein synthesis. J Appl Physiol 106 (5):1730–1739. doi:10.1152/japplphysiol.90395.2008. 90395.2008 [pii]PubMedCrossRef Fujita S, Dreyer HC, Drummond MJ, Glynn EL, Volpi E, Rasmussen BB (2009) Essential amino acid and carbohydrate ingestion before resistance exercise does not enhance postexercise muscle protein synthesis. J Appl Physiol 106 (5):1730–1739. doi:10.​1152/​japplphysiol.​90395.​2008. 90395.2008 [pii]PubMedCrossRef
[103]
Zurück zum Zitat Beelen M, Tieland M, Gijsen AP, Vandereyt H, Kies AK, Kuipers H et al. (2008) Coingestion of carbohydrate and protein hydrolysate stimulates muscle protein synthesis during exercise in young men, with no further increase during subsequent overnight recovery. J Nutr 138 (11):2198–2204. doi:10.3945/jn.108.092924. 138/11/2198 [pii]PubMedCrossRef Beelen M, Tieland M, Gijsen AP, Vandereyt H, Kies AK, Kuipers H et al. (2008) Coingestion of carbohydrate and protein hydrolysate stimulates muscle protein synthesis during exercise in young men, with no further increase during subsequent overnight recovery. J Nutr 138 (11):2198–2204. doi:10.​3945/​jn.​108.​092924. 138/11/2198 [pii]PubMedCrossRef
[104]
Zurück zum Zitat Biolo G, Maggi SP, Williams BD, Tipton KD, Wolfe RR (1995) Increased rates of muscle protein turnover and amino acid transport after resistance exercise in humans. Am J Physiol 268 (3 Pt 1):E514–520PubMed Biolo G, Maggi SP, Williams BD, Tipton KD, Wolfe RR (1995) Increased rates of muscle protein turnover and amino acid transport after resistance exercise in humans. Am J Physiol 268 (3 Pt 1):E514–520PubMed
[105]
Zurück zum Zitat Biolo G, Williams BD, Fleming RY, Wolfe RR (1999) Insulin action on muscle protein kinetics and amino acid transport during recovery after resistance exercise. Diabetes 48 (5):949–957PubMedCrossRef Biolo G, Williams BD, Fleming RY, Wolfe RR (1999) Insulin action on muscle protein kinetics and amino acid transport during recovery after resistance exercise. Diabetes 48 (5):949–957PubMedCrossRef
[106]
Zurück zum Zitat Phillips SM, Tipton KD, Aarsland A, Wolf SE, Wolfe RR (1997) Mixed muscle protein synthesis and breakdown after resistance exercise in humans. Am J Physiol 273 (1 Pt 1):E99–107PubMed Phillips SM, Tipton KD, Aarsland A, Wolf SE, Wolfe RR (1997) Mixed muscle protein synthesis and breakdown after resistance exercise in humans. Am J Physiol 273 (1 Pt 1):E99–107PubMed
[108]
Zurück zum Zitat Hartman JW, Tang JE, Wilkinson SB, Tarnopolsky MA, Lawrence RL, Fullerton AV, Phillips SM (2007) Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightlifters. Am J Clin Nutr 86 (2):373–381. doi:86/2/373 [pii]PubMed Hartman JW, Tang JE, Wilkinson SB, Tarnopolsky MA, Lawrence RL, Fullerton AV, Phillips SM (2007) Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightlifters. Am J Clin Nutr 86 (2):373–381. doi:86/2/373 [pii]PubMed
[109]
Zurück zum Zitat Moore DR, Robinson MJ, Fry JL, Tang JE, Glover EI, Wilkinson SB et al. (2009) Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men. Am J Clin Nutr 89 (1):161–168. doi:10.3945/ajcn.2008.26401. ajcn.2008.26401 [pii]PubMedCrossRef Moore DR, Robinson MJ, Fry JL, Tang JE, Glover EI, Wilkinson SB et al. (2009) Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men. Am J Clin Nutr 89 (1):161–168. doi:10.​3945/​ajcn.​2008.​26401. ajcn.2008.26401 [pii]PubMedCrossRef
[110]
Zurück zum Zitat Tang JE, Moore DR, Kujbida GW, Tarnopolsky MA, Phillips SM (2009) Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men. J Appl Physiol 107 (3):987–992. doi:10.1152/japplphysiol.00076.2009. 00076.2009 [pii]PubMedCrossRef Tang JE, Moore DR, Kujbida GW, Tarnopolsky MA, Phillips SM (2009) Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men. J Appl Physiol 107 (3):987–992. doi:10.​1152/​japplphysiol.​00076.​2009. 00076.2009 [pii]PubMedCrossRef
[111]
Zurück zum Zitat Wilkinson SB, Tarnopolsky MA, Macdonald MJ, Macdonald JR, Armstrong D, Phillips SM (2007) Consumption of fluid skim milk promotes greater muscle protein accretion after resistance exercise than does consumption of an isonitrogenous and isoenergetic soy-protein beverage. Am J Clin Nutr 85 (4):1031–1040. doi:85/4/1031 [pii]PubMed Wilkinson SB, Tarnopolsky MA, Macdonald MJ, Macdonald JR, Armstrong D, Phillips SM (2007) Consumption of fluid skim milk promotes greater muscle protein accretion after resistance exercise than does consumption of an isonitrogenous and isoenergetic soy-protein beverage. Am J Clin Nutr 85 (4):1031–1040. doi:85/4/1031 [pii]PubMed
[112]
Zurück zum Zitat Burk A, Timpmann S, Medijainen L, Vahi M, Oopik V (2009) Time-divided ingestion pattern of casein-based protein supplement stimulates an increase in fat-free body mass during resistance training in young untrained men. Nutr Res 29 (6):405–413. doi:10.1016/j.nutres.2009.03.008. S0271-5317(09)00053-0 [pii]PubMedCrossRef Burk A, Timpmann S, Medijainen L, Vahi M, Oopik V (2009) Time-divided ingestion pattern of casein-based protein supplement stimulates an increase in fat-free body mass during resistance training in young untrained men. Nutr Res 29 (6):405–413. doi:10.​1016/​j.​nutres.​2009.​03.​008. S0271-5317(09)00053-0 [pii]PubMedCrossRef
[113]
Zurück zum Zitat Rehner G, Daniel H (2010) Biochemie der Ernährung. 3. Auflage edn. Spektrum Akademischer Verlag, HeidelbergCrossRef Rehner G, Daniel H (2010) Biochemie der Ernährung. 3. Auflage edn. Spektrum Akademischer Verlag, HeidelbergCrossRef
Metadaten
Titel
Stoffwechselprinzipien der Ernährung
verfasst von
Petra Stuparits
Erich Roth
Karl-Heinz Wagner
Copyright-Jahr
2018
Verlag
Springer Vienna
DOI
https://doi.org/10.1007/978-3-7091-1591-6_13

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Knie-TEP: Kein Vorteil durch antibiotikahaltigen Knochenzement

29.05.2024 Periprothetische Infektionen Nachrichten

Zur Zementierung einer Knie-TEP wird in Deutschland zu über 98% Knochenzement verwendet, der mit einem Antibiotikum beladen ist. Ob er wirklich besser ist als Zement ohne Antibiotikum, kann laut Registerdaten bezweifelt werden.

Häusliche Gewalt in der orthopädischen Notaufnahme oft nicht erkannt

28.05.2024 Häusliche Gewalt Nachrichten

In der Notaufnahme wird die Chance, Opfer von häuslicher Gewalt zu identifizieren, von Orthopäden und Orthopädinnen offenbar zu wenig genutzt. Darauf deuten die Ergebnisse einer Fragebogenstudie an der Sahlgrenska-Universität in Schweden hin.

Fehlerkultur in der Medizin – Offenheit zählt!

28.05.2024 Fehlerkultur Podcast

Darüber reden und aus Fehlern lernen, sollte das Motto in der Medizin lauten. Und zwar nicht nur im Sinne der Patientensicherheit. Eine negative Fehlerkultur kann auch die Behandelnden ernsthaft krank machen, warnt Prof. Dr. Reinhard Strametz. Ein Plädoyer und ein Leitfaden für den offenen Umgang mit kritischen Ereignissen in Medizin und Pflege.

Mehr Frauen im OP – weniger postoperative Komplikationen

21.05.2024 Allgemeine Chirurgie Nachrichten

Ein Frauenanteil von mindestens einem Drittel im ärztlichen Op.-Team war in einer großen retrospektiven Studie aus Kanada mit einer signifikanten Reduktion der postoperativen Morbidität assoziiert.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.