We report a successful, albeit complicated pregnancy with a live-born healthy baby at 28 weeks' gestation, after 10 pregnancy failures, in a 39-year-old patient with a history of liver transplantation and chronic kidney disease with hypertension …
verfasst von:
Leonard Cauchy, Eve Mousty, George-Philippe Pageaux, Olivier Moranne
On January 30, 2020, the World Health Organization (WHO) declared the outbreak of the COVID-19 virus a ‘public health emergency of international concern’ and shortly thereafter a pandemic [ 1 , 2 ]. In response, healthcare systems worldwide …
verfasst von:
Joan Fernando, Ignacio Revuelta, Eva Palou, Rosario Scandurra, Beatriu Bayés, Joan Escarrabill
Hemophagocytic syndrome is a disease resulting from an excessive pathological inflammatory response caused by immune dysfunction, which can lead to cytokine storms and widespread organ dysfunction, including kidney injury. Renal involvement …
Rossella Attini, Gianfranca Cabiddu, Francesca Ciabatti, Benedetta Montersino, Andrea Roberto Carosso, Giuseppe Gernone, Linda Gammaro, Gabriella Moroni, Massimo Torreggiani, Bianca Masturzo, Domenico Santoro, Alberto Revelli, Giorgina Barbara Piccoli, On behalf of the Italian Society of Nephrology’s Project Group on Kidney and Pregnancy
Chronic kidney disease (CKD) is highly prevalent in the United States, impacting 14% of all adults and approximately 40% of all people over the age of 65 [ 1 ]. Progression to end-stage kidney disease (kidney failure) and dialysis treatment results …
verfasst von:
Eleanor Rivera, Nathan Tintle, Raymond R. Townsend, Mahboob Rahman, Sarah J. Schrauben, Maya N. Clark-Cutaia, Mary Hannan, James P. Lash, Katherine Wolfrum, Celestin Missikpode, Karen B. Hirschman
Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are new drugs developed for the treatment of anemia associated with chronic kidney disease (CKD). This class of drugs stimulates endogenous erythropoietin production and, at the …
verfasst von:
Francesco Locatelli, Lucia Del Vecchio, Ciro Esposito, Loreto Gesualdo, Giuseppe Grandaliano, Maura Ravera, Roberto Minutolo, on behalf of the Collaborative Study Group on the Conservative Treatment of CKD of the Italian Society of Nephrology
A 77-year-old man was referred to our nephrology unit for assessment of polyuria and polydipsia. The patient reported persistent sensation of thirst, water craving (daily water intake of 10–12 L), polyuria (10 L/day) and nocturia. He had a medical …
verfasst von:
Rosa Giunta, Luciano Gervasi, Irene Torrisi, Roberta Aliotta, Carmelita Marcantoni
The pathological features of acute and chronic kidney diseases are closely associated with cell death in glomeruli and tubules. Ferroptosis is a form of programmed cell death characterized by iron overload-induced oxidative stress. Ferroptosis has …
verfasst von:
Jia Liu, Jianheng Chen, Jie Lv, Yuhang Gong, Jie Song
Acute kidney injury (AKI) can occur in nearly 50% of patients admitted to the intensive care unit (ICU), and has been associated with a wide range of adverse events [ 1 ]. Therefore, it is not surprising that mortality is higher for many years …
verfasst von:
Florian G. Scurt, Angela Ernst, Alexandra Korda, Carl-Ludwig Fischer-Fröhlich, Anke Schwarz, Jan U. Becker, Christos Chatzikyrkou
Open Access
02.05.2024 | Lessons for the Clinical Nephrologist
A 73-year-old woman on chronic hemodialysis (HD) presented a relapsing itchy rash during her HD sessions (Fig. 1 ). She had been diagnosed with chronic kidney disease (CKD) 7 years earlier, in 2014, presumably due to oxalate nephropathy in enteric …
verfasst von:
Fulvia Zappulo, Miriam Di Nunzio, Gabriele Donati, Anna Scrivo, Anna Laura Croci Chiocchini, Gaetano La Manna
Kidney disease is increasingly becoming a significant worldwide health burden [ 1 ]. The global all-age chronic kidney disease (CKD) mortality increased by 41.5% between 1990 and 2019 [ 2 , 3 ]. There is a growing, unified acknowledgement of an …
verfasst von:
Elin Davies, Andrew Chetwynd, Garry McDowell, Anirudh Rao, Louise Oni
Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers (ACEi/ARBs) are commonly used anti-hypertensive drugs. Recent hypertension guidelines recommend dual combination therapy including ACEi/ARBs as an initial form of …
verfasst von:
Jaeyun Lee, Chan-Young Jung, Hyosang Kim, Hwa Jung Kim, Youngmin Ko, Hyunwook Kwon, Sung Shin, Young Hoon Kim, Su-Kil Park, Chung Hee Baek
Alport syndrome has been linked to three different genes, that is, COL4A3, COL4A4 and COL4A5. It is characterized by progressive and non-specific glomerulosclerosis with irregular thickening of the glomerular basement membrane (GBM). At times, the …
verfasst von:
Nicolas A. D. Bergeron, Alexandre P. Garneau, Mathieu Rousseau-Gagnon, Julie Riopel, Paul Isenring
Patients undergoing maintenance hemodialysis experience a range of symptom clusters and economic burdens, resulting in a lower health-related quality of life (HRQOL) compared to their healthy counterparts [ 1 ]. Physical activity refers to any body …
Patient 1, a 33-year-old woman, was referred to our Unit in November 2018. The patient suffered from recurrent abdominal pain starting from menarche. The crises were not regularly connected with menstrual cycles. During the acute crises, this pain …
verfasst von:
Claudio Carmine Guida, Angela Maria Pellegrino, Aurora Del Mar Perez Ys, Filippo Aucella, CSS Porphiria Study Group
