Rosacea fulminans is a rare disease of unknown cause which occurs exclusively in women years after adolescence. Although the etiology is unknown, immunologic, hormonal, and vascular factors have been suggested. When rosacea fulminans occurs during …

Viral skin infections are common findings in organ transplant recipients. The most important etiological agents are the group of human herpesviruses (HHV), human papillomaviruses (HPV), and molluscum contagiosum virus. HHV that are important in …

Background: Hidradenitis suppurativa is a chronic debilitating skin disease that is recalcitrant to treatment. Objective: The aim of this article was to conduct an evidence-based review of pharmacologic interventions for the treatment of …

Angiotensin-converting enzyme is used as a marker for sarcoid activity. We describe a case of remission of cutaneous and lymphatic sarcoidosis in a patient treated with an ACE inhibitor for congestive heart failure and hypertension; the remission …

Dermatologic presentations of orthopedic diseases are commonly encountered in the dermatology clinic. These disorders often necessitate prompt recognition in order to properly refer for definitive treatment as well as to avoid unnecessary …

Hereditary angioedema is an episodic swelling disorder with autosomal dominant inheritance. Attacks are characterized by nonpitting edema of external or mucosal body surfaces. Patients often present with swelling of the extremities, abdominal …

Mycoplasma pneumoniae-associated mucositis is a rarely described complication of M. pneumoniae infection presenting with ocular, oral, and genital involvement but without the typical skin lesions seen in Stevens- Johnson syndrome.A 27-year-old man …

Lyme borreliosis is a multisystem infectious disease caused by tick-transmitted spirochetes of the Borrelia burgdorferi sensu lato complex. The three characteristic cutaneous manifestations are erythema migrans, borrelial lymphocytoma, and …

Cutaneous warts are common skin lesions caused by human papillomavirus infection. Treatment is aimed at relieving the patient’s physical and psychological discomfort and at preventing the spread of infection by autoinoculation. Among the available …

Background: Since targeted biologic treatments have been introduced for the treatment of plaque-type psoriasis and psoriatic arthritis, switching between different medications has become necessary in selected patients, particularly after treatment …

The acute onset of purple digits is a concerning manifestation and may represent underlying, potentially life-threatening disease. Correctly identifying the etiology of purple digits is essential to proper management, and can aid in the diagnosis …

Background: A favorable benefit-risk profile has been established for adalimumab, with up to 5 years of treatment in 13 clinical trials in patients with moderate to severe chronic plaque psoriasis.Objective: The aim of this analysis was to assess …

IVIg is a safe and effective adjunctive treatment for myasthenia gravis, but there are no well established guidelines for the use of IVIg in this disease, lacking controlled randomized trials to assess its efficacy in homogeneous group of …

A new compound named pinoresinol 4-O-α-l-rhamnopyranosyl (1 → 2)-β-d-glucopyranoside (1) together with six known compounds, isolariciresinol 9-O-β-D-glucopyranoside (2), apigenin 6,8-di-C-β-d-glucopyranoside (3), luteolin 7-O-neohesperidoside (4) …

Subscribers to the Canadian Journal of Anesthesia are invited to read the following article to introduce them to a number of key articles cited in the bibliography. Reading at least the articles preceded by an asterisk (*) allows adequate …

Therapeutic nuclear medicine is rapidly developing as an additional treatment modality in oncology. Its unique characteristics are the systemic, yet selective delivery of radiation doses in target tissues, its non-invasiveness, the relative lack …