Skip to main content
Erschienen in: Current Cardiology Reports 3/2022

17.01.2022 | Ischemic Heart Disease (D Mukherjee, Section Editor)

Cardiovascular Morbidity in Individuals with Impaired FEV1

verfasst von: Joscilin Mathew, Nils Patrick Nickel

Erschienen in: Current Cardiology Reports | Ausgabe 3/2022

Einloggen, um Zugang zu erhalten

Abstract

Purpose of Review

This review is intended to give an overview of the epidemiology of cardiovascular morbidity and mortality in patients with impaired lung function with an emphasis on patients with COPD.

Recent Findings

Despite shared risk factors, lung disease is an emerging independent risk factor for cardiovascular disease and cardio-vascular disease (CVD) outcomes. Both CVD and chronic lung disease contribute significantly to overall mortality. Especially patients with chronic obstructive pulmonary disease (COPD) are at high risk for CVD-related mortality.

Summary

In patients with chronic lung disease, a low index of suspicion should be maintained to assess for CVD and vice versa. Early detection of chronic lung disease as a potentially modifiable CVD risk factor could have important impact on patient outcomes.
Literatur
10.
11.
Zurück zum Zitat Sode BF, Dahl M and Nordestgaard BG. Myocardial infarction and other co-morbidities in patients with chronic obstructive pulmonary disease: a Danish Nationwide Study of 7.4 million individuals. Eur Heart J. 2011;32:2365–2375. https://doi.org/10.1093/eurheartj/ehr338. Sode BF, Dahl M and Nordestgaard BG. Myocardial infarction and other co-morbidities in patients with chronic obstructive pulmonary disease: a Danish Nationwide Study of 7.4 million individuals. Eur Heart J. 2011;32:2365–2375. https://​doi.​org/​10.​1093/​eurheartj/​ehr338.
14.
Zurück zum Zitat •• Duong M, Islam S, Rangarajan S, et al. Mortality and cardiovascular and respiratory morbidity in individuals with impaired FEV1 (PURE): an international, community-based cohort study. Lancet Glob Health. 2019;7:e613-e623. https://doi.org/10.1016/S2214-109X(19)30070-1. FEV1 is an independent predictor of CVD, even across the clinically normal range (mild to moderate impairment). •• Duong M, Islam S, Rangarajan S, et al. Mortality and cardiovascular and respiratory morbidity in individuals with impaired FEV1 (PURE): an international, community-based cohort study. Lancet Glob Health. 2019;7:e613-e623. https://​doi.​org/​10.​1016/​S2214-109X(19)30070-1. FEV1 is an independent predictor of CVD, even across the clinically normal range (mild to moderate impairment).
21.
Zurück zum Zitat Canepa M, Straburzynska-Migaj E, Drozdz J, et al. Characteristics, treatments and 1-year prognosis of hospitalized and ambulatory heart failure patients with chronic obstructive pulmonary disease in the European Society of Cardiology Heart Failure Long-Term Registry. Eur J Heart Fail. 2018;20:100–110. https://doi.org/10.1002/ejhf.964. Canepa M, Straburzynska-Migaj E, Drozdz J, et al. Characteristics, treatments and 1-year prognosis of hospitalized and ambulatory heart failure patients with chronic obstructive pulmonary disease in the European Society of Cardiology Heart Failure Long-Term Registry. Eur J Heart Fail. 2018;20:100–110. https://​doi.​org/​10.​1002/​ejhf.​964.
24.
Zurück zum Zitat • Hohlfeld JM, Vogel-Claussen J, Biller H, et al. Effect of lung deflation with indacaterol plus glycopyrronium on ventricular filling in patients with hyperinflation and COPD (CLAIM): a double-blind, randomised, crossover, placebo-controlled, single-centre trial. Lancet Respir Med. 2018;6:368–378. https://doi.org/10.1016/s2213-2600(18)30054-7. This study demonstrates that bronchodilators have a direct hemodynamic effect on left-ventricular function. Early use of bronchodialtors in patients with COPD could serve as a preventative measure to reduce CVD in patients with COPD. • Hohlfeld JM, Vogel-Claussen J, Biller H, et al. Effect of lung deflation with indacaterol plus glycopyrronium on ventricular filling in patients with hyperinflation and COPD (CLAIM): a double-blind, randomised, crossover, placebo-controlled, single-centre trial. Lancet Respir Med. 2018;6:368–378. https://​doi.​org/​10.​1016/​s2213-2600(18)30054-7. This study demonstrates that bronchodilators have a direct hemodynamic effect on left-ventricular function. Early use of bronchodialtors in patients with COPD could serve as a preventative measure to reduce CVD in patients with COPD.
27.
Zurück zum Zitat Chronic Cor Pulmonale. Report of an expert committee. World Health Organ Tech Rep Ser. 1961;213:35. Chronic Cor Pulmonale. Report of an expert committee. World Health Organ Tech Rep Ser. 1961;213:35.
39.
Zurück zum Zitat Liao KM, Kuo LT, Lu HY. Increased risk of peripheral arterial occlusive diseases in patients with chronic obstructive pulmonary disease: a nationwide study in Taiwan. Int J Chron Obstruct Pulmon Dis. 2019;14:1455–1464. https://doi.org/10.2147/COPD.S202029. Liao KM, Kuo LT, Lu HY. Increased risk of peripheral arterial occlusive diseases in patients with chronic obstructive pulmonary disease: a nationwide study in Taiwan. Int J Chron Obstruct Pulmon Dis. 2019;14:1455–1464. https://​doi.​org/​10.​2147/​COPD.​S202029.
40.
Zurück zum Zitat Houben-Wilke S, Jorres RA, Bals R, et al. Peripheral artery disease and its clinical relevance in patients with chronic obstructive pulmonary disease in the COPD and systemic consequences-comorbidities network study. Am J Respir Crit Care Med. 2017;195:189–197. https://doi.org/10.1164/rccm.201602-0354OC. Houben-Wilke S, Jorres RA, Bals R, et al. Peripheral artery disease and its clinical relevance in patients with chronic obstructive pulmonary disease in the COPD and systemic consequences-comorbidities network study. Am J Respir Crit Care Med. 2017;195:189–197. https://​doi.​org/​10.​1164/​rccm.​201602-0354OC.
49.
Zurück zum Zitat Schnell K, Weiss CO, Lee T, et al. The prevalence of clinically-relevant comorbid conditions in patients with physician-diagnosed COPD: a cross-sectional study using data from NHANES 1999–2008. BMC Pulm Med. 2012;12:26. https://doi.org/10.1186/1471-2466-12-26. Schnell K, Weiss CO, Lee T, et al. The prevalence of clinically-relevant comorbid conditions in patients with physician-diagnosed COPD: a cross-sectional study using data from NHANES 1999–2008. BMC Pulm Med. 2012;12:26. https://​doi.​org/​10.​1186/​1471-2466-12-26.
Metadaten
Titel
Cardiovascular Morbidity in Individuals with Impaired FEV1
verfasst von
Joscilin Mathew
Nils Patrick Nickel
Publikationsdatum
17.01.2022
Verlag
Springer US
Erschienen in
Current Cardiology Reports / Ausgabe 3/2022
Print ISSN: 1523-3782
Elektronische ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-022-01636-1

Weitere Artikel der Ausgabe 3/2022

Current Cardiology Reports 3/2022 Zur Ausgabe

Congenital Heart Disease (RA Krasuski and G Fleming, Section Editors)

Burden and Impact of Arrhythmias in Repaired Tetralogy of Fallot

Congenital Heart Disease (RA Krasuski and G Fleming, Section Editors)

Anesthetic Management in Adults with Congenital Heart Disease

Management of Acute Coronary Syndromes (H Jneid, Section Editor)

Is There a Role for Triple Therapy After ACS?

Peripheral Vascular Disease (WS Jones, Section Editor)

Team-Based Care in Patients with Chronic Limb-Threatening Ischemia

Ein Drittel der jungen Ärztinnen und Ärzte erwägt abzuwandern

07.05.2024 Medizinstudium Nachrichten

Extreme Arbeitsverdichtung und kaum Supervision: Dr. Andrea Martini, Sprecherin des Bündnisses Junge Ärztinnen und Ärzte (BJÄ) über den Frust des ärztlichen Nachwuchses und die Vorteile des Rucksack-Modells.

Vorhofflimmern bei Jüngeren gefährlicher als gedacht

06.05.2024 Vorhofflimmern Nachrichten

Immer mehr jüngere Menschen leiden unter Vorhofflimmern. Betroffene unter 65 Jahren haben viele Risikofaktoren und ein signifikant erhöhtes Sterberisiko verglichen mit Gleichaltrigen ohne die Erkrankung.

Chronisches Koronarsyndrom: Gefahr von Hospitalisierung wegen Herzinsuffizienz

06.05.2024 Herzinsuffizienz Nachrichten

Obwohl ein rezidivierender Herzinfarkt bei chronischem Koronarsyndrom wahrscheinlich die Hauptsorge sowohl der Patienten als auch der Ärzte ist, sind andere Ereignisse womöglich gefährlicher. Laut einer französischen Studie stellt eine Hospitalisation wegen Herzinsuffizienz eine größere Gefahr dar.

Das Risiko für Vorhofflimmern in der Bevölkerung steigt

02.05.2024 Vorhofflimmern Nachrichten

Das Risiko, im Lauf des Lebens an Vorhofflimmern zu erkranken, ist in den vergangenen 20 Jahren gestiegen: Laut dänischen Zahlen wird es drei von zehn Personen treffen. Das hat Folgen weit über die Schlaganfallgefährdung hinaus.

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.