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Erschienen in: American Journal of Clinical Dermatology 4/2017

01.08.2017 | Review Article

Diagnosis and Treatment of Kaposi Sarcoma

verfasst von: Johann W. Schneider, Dirk P. Dittmer

Erschienen in: American Journal of Clinical Dermatology | Ausgabe 4/2017

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Abstract

Kaposi sarcoma (KS) is the most common neoplasm of people living with HIV today. In Sub-Saharan Africa, KS is among the most common cancers in men, overall. Not only HIV-positive individuals present with KS; any immune compromised person infected with KS-associated herpesvirus (KSHV) or human herpesvirus 8 is at risk: the elderly, children in KSHV-endemic areas, and transplant recipients. KS diagnosis is based on detection of the viral protein latency-associated nuclear antigen (LANA) in the biopsy, but not all cases of KS are the same or will respond to the same therapy. Standard KS therapy has not changed in 20 years, but newer modalities are on the horizon and will be discussed.
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Metadaten
Titel
Diagnosis and Treatment of Kaposi Sarcoma
verfasst von
Johann W. Schneider
Dirk P. Dittmer
Publikationsdatum
01.08.2017
Verlag
Springer International Publishing
Erschienen in
American Journal of Clinical Dermatology / Ausgabe 4/2017
Print ISSN: 1175-0561
Elektronische ISSN: 1179-1888
DOI
https://doi.org/10.1007/s40257-017-0270-4

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