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02.05.2022 | Original Article

Effect of photobiomodulation on fatigue in individuals with relapsing–remitting multiple sclerosis: a pilot study

verfasst von: Tamiris Silva, Raquel Candido Alencar, Bruna Cristina de Souza Silva, Elaine Cristina Oliveira Martins Viana, Yara Dadalti Fragoso, Andréa Oliver Gomes, Maria Cristina Chavantes, Alessandro Melo Deana, Juliana Maria Altavista Sagretti Gallo, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Sandra Kalil Bussadori

Erschienen in: Lasers in Medical Science | Ausgabe 8/2022

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Abstract

Multiple sclerosis is an autoimmune disease of the central nervous system characterized by inflammation and destruction of the myelin sheath. Fatigue is one of the main symptoms of this disease, with a negative impact on quality of life and few treatment options. Photobiomodulation is used for several inflammatory conditions and may be beneficial for the treatment of fatigue in individuals with multiple sclerosis. Conduct a pilot study to analyze the effect of photobiomodulation on fatigue in individuals with relapsing–remitting multiple sclerosis. The participants were recruited from the UNINOVE Integrated Health Clinic and randomly allocated to two groups: group 1, administration of photobiomodulation (808 nm, 36 J for 360 s) under the tongue and group 2, administration of photobiomodulation over the radial artery. Fatigue was measured using the Modified Fatigue Impact Scale (MFIS). No significant differences were found regarding the total MFIS score or subscale scores (p < 0.05, two-way ANOVA). Photobiomodulation with the parameters employed in the present study had no effect on fatigue in individuals with multiple sclerosis. ClinicalTrials.gov Identifier: NCT03360487.

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Titel: Effect of photobiomodulation on fatigue in individuals with relapsing–remitting multiple sclerosis: a pilot study
verfasst von: Tamiris Silva
Raquel Candido Alencar
Bruna Cristina de Souza Silva
Elaine Cristina Oliveira Martins Viana
Yara Dadalti Fragoso
Andréa Oliver Gomes
Maria Cristina Chavantes
Alessandro Melo Deana
Juliana Maria Altavista Sagretti Gallo
Kristianne Porta Santos Fernandes
Raquel Agnelli Mesquita-Ferrari
Sandra Kalil Bussadori
Publikationsdatum: 02.05.2022
Verlag: Springer London
Erschienen in: Lasers in Medical Science / Ausgabe 8/2022
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-022-03567-3

Springer Medizin

Abstract

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