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Pediatric Cardiology OnlineFirst articles

25.04.2024 | Research

Evaluation the Effect of Anthracyclines on Cardiac Function in Children Lymphoma Survivors by Left Ventricular Myocardial Work

Anthracycline chemotherapy is associated with the left ventricular (LV) dysfunction, but the conventional echocardiographic parameter is insensitive in detecting subclinical cardiac dysfunction, and the role of echocardiography in children cancer …

verfasst von:
Yuqiong An, Li Xue, Liyuan Xu, Chao Zhang, Yijie Yang, Yong Liu, Ning Ma

25.04.2024 | Research

The Incidence and Relevance of Hematochezia in the Interstage Congenital Heart Population

Necrotizing enterocolitis (NEC) increases morbidity and mortality for infants with single ventricle heart disease (SVHD). While hematochezia often proceeds NEC not all hematochezia progresses to NEC. We aimed to examine the incidence …

verfasst von:
Courtney M. Strohacker, Noah S. Cutler, Sunkyung Yu, Ray E. Lowery, Caren S. Goldberg

Open Access 25.04.2024 | Review

Duct Stenting in Duct-Dependent Systemic Blood Flow, Past, Present, and Future

Arterial duct stenting, pioneered in the early 1990s for newborns with a duct-dependent pulmonary and systemic circulation, has evolved significantly over the past decades. This progressive technique has led to the development of novel therapeutic …

verfasst von:
Dietmar Schranz

22.04.2024 | Research

Fetal Echocardiographic Evaluation of Tricuspid Valve and Right Ventricular Function Including Global Longitudinal Strain in Hypoplastic Left Heart Syndrome and Association with Postnatal Outcomes

Despite significant advancements in the care of patients with hypoplastic left heart syndrome (HLHS) morbidity and mortality remain high. Postnatal right ventricular dysfunction and tricuspid regurgitation (TR) are associated with worse outcomes …

verfasst von:
Benjamin Ittleman, Sarah Lowenstein, Lindsay A. Edwards, Elizabeth Caris, Aarti Bhat, Jeffrey Conwell, Mark Lewin, Bhawna Arya

22.04.2024 | Research

Clarifying the Anatomy of Tetralogy of Fallot with S-shaped Ascending Aorta

We recently encountered several cases of tetralogy of Fallot with an abnormally oriented S-shaped ascending aorta. In this retrospective study, we sought to clarify morphology of this unusual under-recognized variant. Databases were reviewed to …

verfasst von:
Saurabh Kumar Gupta, Aprateem Mukherjee, Niraj Nirmal Pandey, Sivasubramanian Ramakrishnan, Shyam Sunder Kothari, Anita Saxena, Robert H. Anderson

Open Access 19.04.2024 | Review

Initiating a Fetal Cardiac Program from Scratch in Low- and Middle-Income Countries: Structure, Challenges, and Hopes for Solutions

Although fetal cardiac programs are well established in developed countries, establishing an efficient program in low- and middle-income countries (LMICs) is still considered a significant challenge. Substantial obstacles usually face the …

verfasst von:
Shaimaa Rakha

18.04.2024 | Research

How do Age at the Surgery and Birth Weight Influence Post-Operative Anthropometric Parameters in Infants with Surgical Closure of Large Ventricular Septal Defects? A Prospective Cohort Study from a Lower-Middle-Income Country

Closure of the large ventricular septal defects (VSD) in infancy can lead to normalization of growth, but data are limited. Our study is done to assess the growth pattern in different age groups of children and lower birth weight babies after …

verfasst von:
Santosh Wadile, Divya Kondgekar, Ashishkumar Moreshwar Banpurkar, Shahena Parveen Raeen, Komal Kulkarni, Snehal Kulkarni

15.04.2024 | Research

Assessment of Heart Rate Variability in Children with Mitral Valve Prolapse

Mitral valve prolapse (MVP) is defined as more than 2 mm displacement of one or both of the mitral valves toward the left atrium during the left ventricular systole. Its incidence was reported as 2.4% in echocardiographic studies. In addition to …

verfasst von:
Meryem Beyazal, Senem Ozgur, Ilker Ufuk Sayici, Serpil Kaya Celebi

11.04.2024 | Research

Exposure to Endocrine-Disrupting Chemicals and Congenital Heart Diseases: The Pooled Results Based on the Current Evidence

The relationships between maternal exposure to endocrine-disrupting chemicals (EDCs) and congenital heart diseases (CHD) are not elucidated yet. The exposure levels of EDCs are generally estimated based on self-reported questionnaires or …

verfasst von:
Jiangtao Dai, Gang Wang, Chun Wu, Zhengxia Pan, Hongbo Li, Lianju Shen, Yuhao Wu

09.04.2024 | Research

Effect of Maternal Race, Residential Rurality, and Social Vulnerability on Critical Congenital Heart Defect Risk

The development of a congenital heart defect (CHD) is multifactorial, with many cases having an unknown etiology. This study explored whether maternal race and lived environment were associated with an infant being born with a critical CHD. A …

verfasst von:
Katie C. Hall, Jennifer C. Robinson, Masoumeh Karimi, Jung Hye Sung

Open Access 06.04.2024 | Research

Early Post-operative ECG Changes as a Predictor of Post-pericardiotomy Syndrome Following Atrial Septal Defect Repair

To identify risk factors associated with post-pericardiotomy syndrome (PPS) in patients undergoing surgical repair of atrial septal defects (ASD). A single-center retrospective study. Tertiary academic hospital. Included were patients of all ages …

verfasst von:
Kristen Hyberg, Iqbal El-Assaad, Wei Liu, Iqbal El-Assaad, Orkun Baloglu, Howard Heching, William Hanna

05.04.2024 | Research

Aberrant Subclavian Artery in Interrupted Aortic Arch with Severe Aortic Outlet Obstruction: Cerebral Blood Flow as a Possible Determinant of Embryonic Cardiovascular Development?

Aberrant subclavian artery (ASCA) is frequently observed in interrupted aortic arch (IAA) with aortic/subaortic obstruction. Developmental significance of ASCA in IAA in utero remains elusive. Newborns with prenatally diagnosed isolated IAA under …

verfasst von:
Danilo Tadeo Jr., Barham Kakavand, Abdul Bhat, Takeshi Tsuda

Open Access 03.04.2024 | Research

Deep Learning for Automated Measurement of Total Cardiac Volume for Heart Transplantation Size Matching

Total Cardiac Volume (TCV)-based size matching using Computed Tomography (CT) is a novel technique to compare donor and recipient heart size in pediatric heart transplant that may increase overall utilization of available grafts. TCV requires …

verfasst von:
Nicholas A. Szugye, Neeraja Mahalingam, Elanchezhian Somasundaram, Chet Villa, Jim Segala, Michael Segala, Farhan Zafar, David L. S. Morales, Ryan A. Moore

03.04.2024 | Research

ALCAPA in Children with Complex Congenital Heart Disease: A Multicenter Study

We sought to report characteristics and outcomes of children with complex anomalous left coronary artery from the pulmonary artery (ALCAPA) and to compare the outcomes to children with isolated ALCAPA. We performed a retrospective data analysis of …

verfasst von:
Saul Flores, Christine M. Riley, Peter Sassalos, Jennifer Smerling, Katherine Cashen, Christopher W. Mastropietro, the Collaborative Research from the Pediatric Cardiac Intensive Care Society (CoRe-PCICS) Investigators

03.04.2024 | Research

Revisiting Atrioventricular Septal Defects: Exploring Chromosomal Abnormalities, Cardiac and Extracardiac Anomalies in a Contemporary Prenatal Cohort

To estimate if there is an association between partial AVSD with chromosomal abnormalities, cardiac and extracardiac malformations, and to report the outcomes of prenatally diagnosed AVSD in a large, contemporary cohort. This is a retrospective …

verfasst von:
Işıl Ayhan, Oya Demirci, Ali Şahap Odacılar, İlker Kemal Yücel, Ali Karaman

03.04.2024 | Correspondence

Correspondence re: “The Neonatal QRS Complex and Its Association with Left Ventricular Mass”

verfasst von:
James J. Joyce, Sunita J. Ferns

Open Access 03.04.2024 | Research

Update on Prenatal Detection Rate of Critical Congenital Heart Disease Before and During the COVID-19 Pandemic

Prenatal diagnosis of critical congenital heart disease (CCHD) has improved over time, and previous studies have identified CCHD subtype and socioeconomic status as factors influencing rates of prenatal diagnosis. Our objective of this …

verfasst von:
Deepak Gupta, Tiffany Vuong, Shuo Wang, Lisa M. Korst, Jay D. Pruetz

02.04.2024 | Research

Prioritize Variant Reclassification in Pediatric Long QT Syndrome—Time to Revisit

Congenital long QT syndrome (LQTS) is an inherited arrhythmia syndrome associated with sudden cardiac death. Accurate interpretation and classification of genetic variants in LQTS patients are crucial for effective management. All patients with …

verfasst von:
Hei-To Leung, Sit-Yee Kwok, Ka-Yee Kwong, Fong-Ying Shih, Sabrina Tsao, Brian Hon-Yin Chung

Open Access 02.04.2024 | Research

Twinning International Pediatric Cardiology Fellowship Programs: A Transformative Educational Experience for Trainees with Potential for Global Adoption

Over the last decade, having endured the COVID-19 pandemic, education and training in pediatric cardiology have undergone a profound disruptive transformation. Trainees experience considerable stress achieving all the competencies required to …

verfasst von:
Sean T. Kelleher, William B. Kyle, Daniel J. Penny, Jillian Olsen, Lars Nolke, Hugh D. Allen, Colin J. McMahon

01.04.2024 | Research

15-Year Analysis of Surgical Approaches and Outcomes for Coarctation in 132 Neonates and Infants

A variety of surgical approaches exist to treat aortic coarctation in neonates and infants. Our institutional approach is designed to match the surgical approach to the individual anatomy of the patient. The objective of this study is to evaluate …

verfasst von:
Yuriy Stukov, Jeffrey P. Jacobs, Omar M. Sharaf, Giles J. Peek, Andrew D. Pitkin, Susana C. Cruz Beltrán, Dalia Lopez-Colon, Connie S. Nixon, Mark S. Bleiweis