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17.08.2018 | Case Report

Laryngeal Epstein–Barr Virus-Associated Smooth Muscle Tumor in an Undernourished Child

verfasst von: Ciro Dantas Soares, Roman Carlos, Juan Pablo Díaz Molina, Thayná Melo de Lima Morais, Oslei Paes de Almeida

Erschienen in: Head and Neck Pathology | Ausgabe 4/2019

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Abstract

Smooth muscle tumors associated with Epstein–Barr virus infections (EBV–SMT) of laryngeal origin are exceedingly rare and have been reported in few adult patients, but not in children. This reported case describes a lesion found in the larynx of an 8-year-old Guatemalan undernourished girl. Microscopically, the lesion showed a highly cellular mesenchymal spindle cell tumor, containing frequent lymphocytes. The immunohistochemical analysis revealed positivity for α-smooth muscle actin and h-caldesmon. In addition, most of the tumor cells were positive for EBV by in situ hybridization. To the best of the author’s knowledge, this is the first literature-reported case of laryngeal EBV–SMT occurring in an undernourished child.

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Titel: Laryngeal Epstein–Barr Virus-Associated Smooth Muscle Tumor in an Undernourished Child
verfasst von: Ciro Dantas Soares
Roman Carlos
Juan Pablo Díaz Molina
Thayná Melo de Lima Morais
Oslei Paes de Almeida
Publikationsdatum: 17.08.2018
Verlag: Springer US
Erschienen in: Head and Neck Pathology / Ausgabe 4/2019
Elektronische ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-018-0960-0

Springer Medizin

Laryngeal Epstein–Barr Virus-Associated Smooth Muscle Tumor in an Undernourished Child

Abstract

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Abstract

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