nach oben

international journal of stomatology & occlusion medicine

Erschienen in:

01.03.2013 | review article

Periodontal disease and obesity

verfasst von: Aravind Kumar P, Mohan Kumar P, Krishna Rao A, Krishna Dileep G

Erschienen in: international journal of stomatology & occlusion medicine | Ausgabe 1/2013

Einloggen, um Zugang zu erhalten

Abstract

Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have an adverse effect on health leading to reduced life expectancy and/or increased health problems. As obesity is a multifaceted condition it has been implicated as a significant risk factor for numerous diseases, such as hypertension, cardiovascular disease and type 2 diabetes mellitus. Recently it has been found that obesity also appears to participate in the multifactorial etiology of periodontitis through increased production of reactive oxygen species and an increase in inflammatory cytokines. The association between impaired lipid metabolism and periodontitis still needs to be established. This review explains the mechanisms that link hyperlipidemia to periodontitis, which is probably related to the exacerbated proinflammatory changes in periodontal tissues.

Newman MG, Takei HH, Carranza FA. Textbook of clinical periodontology. 11th ed. Elsevier; pp. 127, 355.

Scannapieco FA. Position Paper of the AAP. Periodontal disease as a potential risk factorfor systemic diseases. J Periodontol 1998;69:841–50.

Si Y, Fan H, Song Y, Zhou X, Zhang J, Wang Z. Association between periodontitis and chronic obstructive pulmonary disease in a Chinese population. J Periodontol. 2012;83:1288–96.PubMedCrossRef

Expert panel. Executive summary of the clinical guidelines on the identification, evaluation and treatment of overweight and obesity in adults. Arch Intern Med. 1998;158:1855–67.CrossRef

World Health Organization. Diet, nutrition and the prevention of chronic diseases. WHO Tech Rep Ser. 2003;916(i-viii):1–149 (backcover).

Iwata T, Kantarci A, Yagi M, Jackson T, Hasturk H, Kurihara H, Van Dyke TE. Ceruloplasmin induces polymorphonuclear leukocyte priming in localized aggressive periodontitis. J Periodontol. 2009;80(8):1300–6.PubMedCrossRef

Kershaw EE, Flier JS. Adipose tissue as an endocrine organ. J Clin Endocrinol Metab. 2004;89:2548–56.PubMedCrossRef

Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature. 1998;395:763–70.PubMedCrossRef

Lord GM, Matarese G, Howard JK, Baker RJ, Bloom SR, Lechler RI. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature. 1998;27:897–901.

10.

Ouch N, Parker JL, Lugus JJ, Walsh, K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol. 2011;11:85–97.CrossRef

11.

Johnson RB, Serio FG. Leptin within healthy and diseased human gingiva. J Periodontol. 2001;72:1254–7.PubMedCrossRef

12.

Ryo M, Nakamura T, Kihara S, Kumada M, Shibazaki S, Takahashi. Adiponectin as a biomarker of the metabolic syndrome. Circ J. 2004;68:975–81.PubMedCrossRef

13.

Yamaguchi N, Hamachi T, Kamio N, Akifusa S, Masuda K, Nakamura Y, Nonaka K, Maeda K. Expression levels of adiponectin receptors and periodontitis. J Periodontal Res. 2010;45:296–300.PubMedCrossRef

14.

Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance. Science. 1993;259:87–91.PubMedCrossRef

15.

Preshaw PM, Taylor JJ. How has research into cytokine interactions and their role in driving immune responses impacted our understanding of periodontitis? J Clin Periodontol. 2011;38:60–84.PubMedCrossRef

16.

Mavri A, Alessi MC, Bastelica D, Geel-Georgelin O, Fina F, Sentocnik JT, Stegnar M, Juhan-Vague I. Subcutaneous abdominal, but not femoral fat expression of plasminogen activator inhibitor-1 (PAI-1) is related to plasma PAI-1 levels and insulin resistance and decreases after weight loss. Diabetologia. 2001;44:2025–31.PubMedCrossRef

17.

Miyazawa-Hoshimoto S, Takahashi K, Bujo H, Hashimoto N, Saito Y. Elevated serum vascular endothelial growth factor is associated with visceral fat accumulation in human obese subjects. Diabetologia. 2003;46:1483–8.PubMedCrossRef

18.

Reilly MP, Iqbal N, Schutta M, Wolfr ML, Scally M, Localio AR, Rader DJ, Kimmel SE. Plasma leptin levels are associated with coronary atherosclerosis in type 2 diabetes. J Clin Endocrinol Metab. 2004;89:3872–8.PubMedCrossRef

19.

Saito T, Shimazaki Y, Koga T, Tsuzuki M, Ohshima A. Relationship between upper body obesity and periodontitis. J Den Res. 2001;80:1631–6.CrossRef

20.

Bokarewa M, Nagaev I, Dahlberg L, Smith U, Tarkowski T. Resistin, an adipokine with potent proinflammatory properties. J Immunol. 2005;174:5789–95.PubMed

21.

Kawanami D, Maemura K, Takeda N, et al. Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: a new insight into adipocytokine--endothelial cell interactions. Biochem Biophys Res Commun. 2004;314:415–9.PubMedCrossRef

22.

Saito T, Shimazaki Y. Metabolic disorders related to obesity and periodontal disease. Periodontol 2000. 2007;43:254–66.PubMedCrossRef

23.

Saito T, Shimazaki Y, Kiyohara Y, Kato I, Kubo M, Iida M. Relationship between obesity, glucose tolerance and periodontal disease in Japanese women. The Hisayama study. J Periodontol Res. 2005;40:346–53.CrossRef

24.

Perlstein MI, Bissada NF. Influence of obesity and hypertension on the severity of periodontitis in rats. Oral Surg Oral Med Oral Pathol. 1977;43:707–19.PubMedCrossRef

25.

Saito T, Shimazaki Y, Sakamoto M. Obesity and periodontitis [letter]. N Engl J Med. 1998;339:482–3.PubMedCrossRef

26.

Nakamura T, Tokunaga K, Shimomura I, et al. Contribution of visceral fat accumulation to the development of coronary artery disease in non-obese men. Atherosclerosis. 1994;107:239–46.PubMedCrossRef

27.

Banerji MA, Buckley MC, Chaiken RL, et al. Liver fat, serum triglycerides and visceral adipose tissue in insulin-sensitive and insulin-resistant black men with NIDDM. Int J Obes Relat Metab Disord. 1995;19:846–50.PubMed

28.

Ito H, Ohshima A, Ohto N, et al. Relation between body composition and age in healthy Japanese subjects. Eur Clin Nutr. 2001;55:462–70.CrossRef

29.

Tessari P. Changes in protein, carbohydrate, and fat metabolism with aging: possible role of insulin. Nutr Rev. 2000;58:11–9.PubMedCrossRef

30.

Torrungruang K, Tamsailom S, Rojanasomsith K, Sutdhibhisal S, Nisapakultorn K, Vanichjakvong O, Prapakamol S, Premsirinirund T, Pusiri T, Jaratkulangkoon O, Unkurapinun N, Sritara P. Risk indicators of periodontal disease in older Thai adults. J Periodontol. 2005;76:558–65.PubMedCrossRef

31.

Al-Zahrani MS, Bissada NF, Borawskit EA Obesity and periodontal disease in young, middle-aged, and older adults. J Periodontol. 2003;74:610–5.PubMedCrossRef

32.

Alabdulkarim M, Bissada N, Al-Zahrani M, Ficara A, Siegel B. Alveolar bone loss in obese subjects. J Int Acad Periodontol. 2005;7:34–8.PubMed

33.

Socransky SS, Haffajee AD. Periodontal microbial ecology. Periodontol 2000. 2005;38:135–87.PubMedCrossRef

34.

Kuzuya T, Nakagawa S, Satoh J, Kanazawa Y, Iwamoto Y, Kobayashi M, Nanjo K, SasakiA, Seino Y. Report of the committee on the classification and diagnostic criteria of diabetes mellitus. Diabetes Res Clin Pract. 2002;55:65–85.PubMedCrossRef

35.

Nishimura F, Kono T, Fujimoto C, et al. Negative effects of chronic inflammatory periodontal disease on diabetes mellitus. J Int Acad Periodontol. 2000;2:49–55.PubMed

36.

Lundin M, Yucel-Lindberg T, Dahllof G, Marcus C, Modeer T. Correlation between TNFalpha in gingival crevicular fluid and body mass index in obese subjects. Acta Odontol Scand. 2004;62:273–7.PubMedCrossRef

37.

Kim E-J, Jin B-H, Bae K-H. Periodontitis and obesity: a study of the fourth Korean national health and nutrition examination survey. J Periodontal. 2011;82:533–42.

38.

Perri R, Nares S, Zhang S, Barros SP, Offenbacher S. MicroRNA modulation in obesity and periodontitis. J Dent Res. 2012;91(1):33–8.PubMedCrossRef

39.

Ritchie CS. Obesity and periodontal disease. Periodontol 2000. 2007;44:154–63.PubMedCrossRef

40.

Livingston EH. Procedure, incidence and complication rates of bariatric surgery in the United States. Am J Surg. 2004;188:105–10.PubMedCrossRef

41.

Whitaker RC, Dietz WH. Role of the prenatal environment in the development of obesity. J Pediatr. 1998;132:768–76.PubMedCrossRef

Titel: Periodontal disease and obesity
verfasst von: Aravind Kumar P
Mohan Kumar P
Krishna Rao A
Krishna Dileep G
Publikationsdatum: 01.03.2013
Verlag: Springer Vienna
Erschienen in: international journal of stomatology & occlusion medicine / Ausgabe 1/2013
Print ISSN: 1867-2221
Elektronische ISSN: 1867-223X
DOI: https://doi.org/10.1007/s12548-012-0069-0

Neu im Fachgebiet Zahnmedizin

19.04.2024 | Vorhofflimmern | Nachrichten

Newsletter bestellen

Springer Medizin

Periodontal disease and obesity

Abstract

Neu im Fachgebiet Zahnmedizin

Parodontalbehandlung verbessert Prognose bei Katheterablation

Invasive Zahnbehandlung: Wann eine Antibiotikaprophylaxe vor infektiöser Endokarditis schützt

Zell-Organisatoren unter Druck: Mechanismen des embryonalen Zahnwachstums aufgedeckt

Die Oralprophylaxe & Kinderzahnheilkunde umbenannt

Newsletter

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 1/2013

Bimaxillary surgical treatment in a young adult withsevere protrusion and compromised periodontium

Florid cemento-osseous dysplasia complicated by chronic diffuse osteomyelitis in the maxilla

Engineering analyses of the link between occlusion and temporomandibular joint disorders

Prosthetic rehabilitation for a patient with systemic sclerosis

Propositions for a cognitive behavioral approach to bruxism management

Unicystic ameloblastoma

Neu im Fachgebiet Zahnmedizin

Parodontalbehandlung verbessert Prognose bei Katheterablation

Invasive Zahnbehandlung: Wann eine Antibiotikaprophylaxe vor infektiöser Endokarditis schützt

Zell-Organisatoren unter Druck: Mechanismen des embryonalen Zahnwachstums aufgedeckt

Die Oralprophylaxe & Kinderzahnheilkunde umbenannt

Newsletter