Spezifische Immuntherapie bei Allergien

Zurück zum Zitat Ege MJ, Mayer M, Normand AC et al. Exposure to environmental microorganisms and childhood asthma. N Eng J Med. 2011;364(8):701–9CrossRef Ege MJ, Mayer M, Normand AC et al. Exposure to environmental microorganisms and childhood asthma. N Eng J Med. 2011;364(8):701–9CrossRef

Zurück zum Zitat Stein MM, Hrusch CL, Gozdz J et al. Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children. N Eng J Med. 2016;375(5):411–21CrossRef Stein MM, Hrusch CL, Gozdz J et al. Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children. N Eng J Med. 2016;375(5):411–21CrossRef

Zurück zum Zitat Noon, L Prophylactic inoculation against hay fever. Lancet. 1911;1:1572–3CrossRef Noon, L Prophylactic inoculation against hay fever. Lancet. 1911;1:1572–3CrossRef

Zurück zum Zitat Pfaar O, Bachert C, Bufe A et al. Guideline on allergen-specific immunotherapy in IgE-mediated allergic diseases: S2k Guideline of the German Society for Allergology and Clinical Immunology (DGAKI), the Society for Pediatric Allergy and Environmental Medicine (GPA), the Medical Association of German Allergologists (AeDA), the Austrian Society for Allergy and Immunology (OGAI), the Swiss Society for Allergy and Immunology (SGAI), the German Society of Dermatology (DDG), the German Society of Oto- Rhino-Laryngology, Head and Neck Surgery (DGHNO-KHC), the German Society of Pediatrics and Adolescent Medicine (DGKJ), the Society for Pediatric Pneumology (GPP), the German Respiratory Society (DGP), the German Association of ENT Surgeons (BV-HNO), the Professional Federation of Paediatricians and Youth Doctors (BVKJ), the Federal Association of Pulmonologists (BDP) and the German Dermatologists Association (BVDD). Allergo J Int. 2014;23(8):282–319CrossRef Pfaar O, Bachert C, Bufe A et al. Guideline on allergen-specific immunotherapy in IgE-mediated allergic diseases: S2k Guideline of the German Society for Allergology and Clinical Immunology (DGAKI), the Society for Pediatric Allergy and Environmental Medicine (GPA), the Medical Association of German Allergologists (AeDA), the Austrian Society for Allergy and Immunology (OGAI), the Swiss Society for Allergy and Immunology (SGAI), the German Society of Dermatology (DDG), the German Society of Oto- Rhino-Laryngology, Head and Neck Surgery (DGHNO-KHC), the German Society of Pediatrics and Adolescent Medicine (DGKJ), the Society for Pediatric Pneumology (GPP), the German Respiratory Society (DGP), the German Association of ENT Surgeons (BV-HNO), the Professional Federation of Paediatricians and Youth Doctors (BVKJ), the Federal Association of Pulmonologists (BDP) and the German Dermatologists Association (BVDD). Allergo J Int. 2014;23(8):282–319CrossRef

Zurück zum Zitat Bellinghausen, I, Metz G, Enk AH et al. Insect venom immunotherapy induces interleukin-10 production and a Th2-to-Th1 shift, and changes surface marker expression in venom-allergic subjects. Eur J Immunol. 1997;27(5):1131–9CrossRef Bellinghausen, I, Metz G, Enk AH et al. Insect venom immunotherapy induces interleukin-10 production and a Th2-to-Th1 shift, and changes surface marker expression in venom-allergic subjects. Eur J Immunol. 1997;27(5):1131–9CrossRef

Zurück zum Zitat Barzaghi F, Passerini L, Bacchetta R. Immune dysregulation, polyendocrinopathy, enteropathy, x-linked syndrome: a paradigm of immunodeficiency with autoimmunity. Front Immunol. 2012;3:211CrossRef Barzaghi F, Passerini L, Bacchetta R. Immune dysregulation, polyendocrinopathy, enteropathy, x-linked syndrome: a paradigm of immunodeficiency with autoimmunity. Front Immunol. 2012;3:211CrossRef

Zurück zum Zitat Bacher P, Scheffold A. New technologies for monitoring human antigen-specific T cells and regulatory T cells by flow-cytometry. Curr Opinion in Pharm. 2015;23:17–24CrossRef Bacher P, Scheffold A. New technologies for monitoring human antigen-specific T cells and regulatory T cells by flow-cytometry. Curr Opinion in Pharm. 2015;23:17–24CrossRef

Zurück zum Zitat Bacher P, Heinrich F, Stervbo U et al. Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans. Cell. 2016;167(4):1067–78.e16CrossRef Bacher P, Heinrich F, Stervbo U et al. Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans. Cell. 2016;167(4):1067–78.e16CrossRef

Zurück zum Zitat Norman PS, Van Metre TE The safety of allergenic immunotherapy. J Allergy Clin Immunol. 1990;85(2):522–5CrossRef Norman PS, Van Metre TE The safety of allergenic immunotherapy. J Allergy Clin Immunol. 1990;85(2):522–5CrossRef

Zurück zum Zitat Bufe A, Eberle P, Franke-Beckmann E et al. Safety and efficacy in children of an SQ-standardized grass allergen tablet for sublingual immunotherapy. J Allergy Clin Immunol. 2009;123(1):167–173.e7CrossRef Bufe A, Eberle P, Franke-Beckmann E et al. Safety and efficacy in children of an SQ-standardized grass allergen tablet for sublingual immunotherapy. J Allergy Clin Immunol. 2009;123(1):167–173.e7CrossRef

Zurück zum Zitat Dhami S, Zaman H, Varga EM et al. Allergen immunotherapy for insect venom allergy: a systematic review and meta-analysis. Allergy. 2017;72(3):342–65CrossRef Dhami S, Zaman H, Varga EM et al. Allergen immunotherapy for insect venom allergy: a systematic review and meta-analysis. Allergy. 2017;72(3):342–65CrossRef

Zurück zum Zitat Sturm GJ, Varga EM, Roberts G et al. EAACI guidelines on allergen immunotherapy: Hymenoptera venom allergy. Allergy. 2018;73(4):744–64CrossRef Sturm GJ, Varga EM, Roberts G et al. EAACI guidelines on allergen immunotherapy: Hymenoptera venom allergy. Allergy. 2018;73(4):744–64CrossRef

Zurück zum Zitat Dhami S, Nurmatov U, Arasi S et al. Allergen immunotherapy for allergic rhinoconjunctivitis: A systematic review and meta-analysis. Allergy. 2017;72(11):1597–631CrossRef Dhami S, Nurmatov U, Arasi S et al. Allergen immunotherapy for allergic rhinoconjunctivitis: A systematic review and meta-analysis. Allergy. 2017;72(11):1597–631CrossRef

Zurück zum Zitat Roberts G, Pfaar O, Akdis CA et al. EAACI Guidelines on Allergen Immunotherapy: Allergic rhinoconjunctivitis. Allergy. 2018;73(4):765–98CrossRef Roberts G, Pfaar O, Akdis CA et al. EAACI Guidelines on Allergen Immunotherapy: Allergic rhinoconjunctivitis. Allergy. 2018;73(4):765–98CrossRef

Zurück zum Zitat Dhami S, Kakourou A, Asamoah F et al. Allergen immunotherapy for allergic asthma: A systematic review and meta-analysis. Allergy. 2017;72(12):1825–48CrossRef Dhami S, Kakourou A, Asamoah F et al. Allergen immunotherapy for allergic asthma: A systematic review and meta-analysis. Allergy. 2017;72(12):1825–48CrossRef

Zurück zum Zitat Virchow JC, Backer V, Kuna P et al. Efficacy of a House Dust Mite Sublingual Allergen Immunotherapy Tablet in Adults With Allergic Asthma: A Randomized Clinical Trial. JAMA. 2016;315(16):1715–25CrossRef Virchow JC, Backer V, Kuna P et al. Efficacy of a House Dust Mite Sublingual Allergen Immunotherapy Tablet in Adults With Allergic Asthma: A Randomized Clinical Trial. JAMA. 2016;315(16):1715–25CrossRef

Zurück zum Zitat Klimek L, Pfaar O, Worm M. New opportunities for allergen immunotherapy using synthetic peptide immuno-regulatory epitopes (SPIREs). Expert Rev Clin Immunol. 2016:1–13 Klimek L, Pfaar O, Worm M. New opportunities for allergen immunotherapy using synthetic peptide immuno-regulatory epitopes (SPIREs). Expert Rev Clin Immunol. 2016:1–13