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Erschienen in: Current Infectious Disease Reports 5/2011

01.10.2011

Soft Tissue Infections Caused by Marine Bacterial Pathogens: Epidemiology, Diagnosis, and Management

verfasst von: Renato Finkelstein, Ilana Oren

Erschienen in: Current Infectious Disease Reports | Ausgabe 5/2011

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Abstract

Skin and soft tissue infections (SSTIs) are one of the most common infection syndromes and may be caused by a large number of microorganisms. Some principles of aquatic injuries are different than those of land-based trauma. Wounds sustained in marine environment are exposed to a milieu of bacteria rarely encountered in different settings. These include Vibrio spp., Aeromonas spp., Shewanella spp., Erysipelothrix rhusiopathiae, Mycobacterium marinum, Streptococcus iniae, and other microbes. Failure to recognize and treat these uncommon pathogens in a timely manner may result in significant morbidity or death. These infections are frequently contracted as a result of recreational swimming, fishing injuries, or seafood handling. The spectrum of manifestations is wide, varying from cases of mild cellulitis, to severe life-threatening necrotizing fasciitis requiring radical surgery, to sepsis and death. This review will focus on the epidemiology, clinical manifestations, and treatment of SSTIs caused by the most important marine pathogens.
Literatur
1.
Zurück zum Zitat • Dryden MS. Complicated skin and soft tissue infection. J Antimicrob Chemother. 2010;65(Suppl 3):iii35–44. This is a recent and complete overview of complicated skin and soft tissue infection, including those caused by less common pathogens.PubMedCrossRef • Dryden MS. Complicated skin and soft tissue infection. J Antimicrob Chemother. 2010;65(Suppl 3):iii35–44. This is a recent and complete overview of complicated skin and soft tissue infection, including those caused by less common pathogens.PubMedCrossRef
2.
Zurück zum Zitat Di Nubile MJ, Lipsky BA. Complicated infections of the skin and skin structures: when the infection is more than skin deep. J Antimicrob Chemother. 2004;53 Suppl 2:ii37–50.CrossRef Di Nubile MJ, Lipsky BA. Complicated infections of the skin and skin structures: when the infection is more than skin deep. J Antimicrob Chemother. 2004;53 Suppl 2:ii37–50.CrossRef
3.
Zurück zum Zitat Stevens DL, Bisno AL, Chambers H, et al. Practice guidelines for the diagnosis and management of skin and soft-tissue infections. Clin Infect Dis. 2005;41:1373–406.PubMedCrossRef Stevens DL, Bisno AL, Chambers H, et al. Practice guidelines for the diagnosis and management of skin and soft-tissue infections. Clin Infect Dis. 2005;41:1373–406.PubMedCrossRef
4.
Zurück zum Zitat Eron LJ, Lipsky BA, Low DE, et al. Managing skin and soft tissue infections: expert panel recommendations on key decision points. J Antimicrob Chemother. 2003;52 Suppl 1:i3–i17.PubMedCrossRef Eron LJ, Lipsky BA, Low DE, et al. Managing skin and soft tissue infections: expert panel recommendations on key decision points. J Antimicrob Chemother. 2003;52 Suppl 1:i3–i17.PubMedCrossRef
5.
Zurück zum Zitat Pomeroy LR. The microbial food web. Oceanus. 1992;35(3):28–35. Pomeroy LR. The microbial food web. Oceanus. 1992;35(3):28–35.
6.
Zurück zum Zitat Haddad Jr V, Lupi O, Lonza JP, Tyring SK. Tropical dermatology: marine and aquatic dermatology. J Am Acad Dermatol. 2009;61:733–50.PubMedCrossRef Haddad Jr V, Lupi O, Lonza JP, Tyring SK. Tropical dermatology: marine and aquatic dermatology. J Am Acad Dermatol. 2009;61:733–50.PubMedCrossRef
7.
Zurück zum Zitat Kueh CSW, Kutarski P, Brunton M. Contaminated marine wounds—the risk of acquiring acute bacterial infection from marine recreational beaches. J Appl Bacteriol. 1992;73:412–20.PubMed Kueh CSW, Kutarski P, Brunton M. Contaminated marine wounds—the risk of acquiring acute bacterial infection from marine recreational beaches. J Appl Bacteriol. 1992;73:412–20.PubMed
8.
Zurück zum Zitat Auerbach PS, Yajko DM, Nassos PS, et al. Bacteriology of the marine environment: implications for clinical therapy. Ann Emerg Med. 1987;16:643–9.PubMedCrossRef Auerbach PS, Yajko DM, Nassos PS, et al. Bacteriology of the marine environment: implications for clinical therapy. Ann Emerg Med. 1987;16:643–9.PubMedCrossRef
9.
Zurück zum Zitat Noonburg GE. Management of extremity trauma and related infections occurring in the aquatic environment. J Am Acad Orthop Surg. 2005;13:243–53.PubMed Noonburg GE. Management of extremity trauma and related infections occurring in the aquatic environment. J Am Acad Orthop Surg. 2005;13:243–53.PubMed
10.
Zurück zum Zitat Reed KC, Crowel MC. Skin and soft tissue infections after injury in ocean: culture methods and antibiotic therapy for marine bacteria. Mil Med. 1999;164:198–201.PubMed Reed KC, Crowel MC. Skin and soft tissue infections after injury in ocean: culture methods and antibiotic therapy for marine bacteria. Mil Med. 1999;164:198–201.PubMed
11.
Zurück zum Zitat Buck JD, Spotte S, Gadbaw JJ, Jr. Bacteriology of teeth from great white shark: potential medical implications for shark bite victims. J Clin Microbiol. 1984;849–51. Buck JD, Spotte S, Gadbaw JJ, Jr. Bacteriology of teeth from great white shark: potential medical implications for shark bite victims. J Clin Microbiol. 1984;849–51.
12.
Zurück zum Zitat Hlady WG, Klontz K. The epidemiology of Vibrio infections in Florida, 1981–1993. J Infect Dis. 1996;173:1176–83.PubMedCrossRef Hlady WG, Klontz K. The epidemiology of Vibrio infections in Florida, 1981–1993. J Infect Dis. 1996;173:1176–83.PubMedCrossRef
13.
Zurück zum Zitat Blake P, Weaver R, Hollis D. Diseases of humans (other than cholera) caused by vibrio. Annu Rev Microbiol. 1980;34:341–67.PubMedCrossRef Blake P, Weaver R, Hollis D. Diseases of humans (other than cholera) caused by vibrio. Annu Rev Microbiol. 1980;34:341–67.PubMedCrossRef
14.
Zurück zum Zitat Feldhusen F. The role of seafood in bacterial foodbourne diseases. Microbes Infect. 2000;2:1651–60.PubMedCrossRef Feldhusen F. The role of seafood in bacterial foodbourne diseases. Microbes Infect. 2000;2:1651–60.PubMedCrossRef
15.
Zurück zum Zitat • Jones MK, Oliver JD. Vibrio vulnificus: disease and pathogenesis. Infect Immun. 2009;77:1723–33. This minireview includes an in-depth discussion on the physiologic characteristics of Vibrio vulnificus.PubMedCrossRef • Jones MK, Oliver JD. Vibrio vulnificus: disease and pathogenesis. Infect Immun. 2009;77:1723–33. This minireview includes an in-depth discussion on the physiologic characteristics of Vibrio vulnificus.PubMedCrossRef
16.
Zurück zum Zitat Oliver JD. Wound infections caused by Vibrio vulnificus and other marine bacteria. Epidemiol Infect. 2005;133:383–91.PubMedCrossRef Oliver JD. Wound infections caused by Vibrio vulnificus and other marine bacteria. Epidemiol Infect. 2005;133:383–91.PubMedCrossRef
17.
Zurück zum Zitat • Dechet AM, Yu PA, Koram N, Painter J. Nonfoodborne Vibrio infections: An important cause of morbidity and mortality in the United States, 1997–2006. Clin Infect Dis. 2008;46:970–6. This study represents the largest series of nonfoodborne Vibrio infections (including soft tissue infections) reported. PubMedCrossRef • Dechet AM, Yu PA, Koram N, Painter J. Nonfoodborne Vibrio infections: An important cause of morbidity and mortality in the United States, 1997–2006. Clin Infect Dis. 2008;46:970–6. This study represents the largest series of nonfoodborne Vibrio infections (including soft tissue infections) reported. PubMedCrossRef
18.
Zurück zum Zitat Bisharat N, Agmon V, Finkelstein R, et al. Clinical, epidemiological, and microbiological features of Vibrio vulnificus biogroup 3 causing outbreaks of wound infection and bacteraemia in Israel. Israel Vibrio Study Group. Lancet. 1999;354:1421–4.PubMedCrossRef Bisharat N, Agmon V, Finkelstein R, et al. Clinical, epidemiological, and microbiological features of Vibrio vulnificus biogroup 3 causing outbreaks of wound infection and bacteraemia in Israel. Israel Vibrio Study Group. Lancet. 1999;354:1421–4.PubMedCrossRef
19.
Zurück zum Zitat Park K-H, Jung S-I, Jung Y-S, et al. Marine bacteria as a leading cause of necrotizing fasciitis in coastal areas of South Korea. Am J Trop Med Hyg. 2009;80:646–50.PubMed Park K-H, Jung S-I, Jung Y-S, et al. Marine bacteria as a leading cause of necrotizing fasciitis in coastal areas of South Korea. Am J Trop Med Hyg. 2009;80:646–50.PubMed
20.
Zurück zum Zitat Zaidenstein R, Sadik C, Lerner L, et al. Clinical characteristics and molecular subtyping of Vibrio vulnificus illnesses, Israel. Em Infect Dis. 2008;14:1875–82.CrossRef Zaidenstein R, Sadik C, Lerner L, et al. Clinical characteristics and molecular subtyping of Vibrio vulnificus illnesses, Israel. Em Infect Dis. 2008;14:1875–82.CrossRef
21.
Zurück zum Zitat Koenig KL, Mueller J, Rose T. Vibrio vulnificus: hazard on half shell. West J Med. 1991;155:400–3.PubMed Koenig KL, Mueller J, Rose T. Vibrio vulnificus: hazard on half shell. West J Med. 1991;155:400–3.PubMed
22.
Zurück zum Zitat Amaro C, Biosca EG. Vibrio vulnificus biotype 2, pathogenic for eels, is also an opportunistic pathogen for humans. Appl Environ Microbiol. 1996;62:1454–7.PubMed Amaro C, Biosca EG. Vibrio vulnificus biotype 2, pathogenic for eels, is also an opportunistic pathogen for humans. Appl Environ Microbiol. 1996;62:1454–7.PubMed
23.
Zurück zum Zitat Tison DL, Nishibuchi M, Greenwood JD, Seidler RJ. Vibrio vulnificus biogroup 2: new biogroup pathogenic for eels. Appl Environ Microbiol. 1982;44:640–6.PubMed Tison DL, Nishibuchi M, Greenwood JD, Seidler RJ. Vibrio vulnificus biogroup 2: new biogroup pathogenic for eels. Appl Environ Microbiol. 1982;44:640–6.PubMed
24.
Zurück zum Zitat Chuang Y-C, Yuan C-Y, Liu C-Y, et al. Vibrio vulnificus infection in Taiwan: Report of 28 cases and review of clinical manifestations and treatment. Clin Infect Dis. 1992;15:271–6.PubMedCrossRef Chuang Y-C, Yuan C-Y, Liu C-Y, et al. Vibrio vulnificus infection in Taiwan: Report of 28 cases and review of clinical manifestations and treatment. Clin Infect Dis. 1992;15:271–6.PubMedCrossRef
25.
Zurück zum Zitat Howard RJ, Bennett NT. Infections caused by halophilic marine Vibrio bacteria. Ann Surg. 1993;217:525–31.PubMedCrossRef Howard RJ, Bennett NT. Infections caused by halophilic marine Vibrio bacteria. Ann Surg. 1993;217:525–31.PubMedCrossRef
26.
Zurück zum Zitat Shapiro RL, Altekruse S, Hutwagner L, the Vibrio Working Group, et al. The role of gulf coast oysters harvested in warmer months in Vibrio vulnificus infections in the United States, 1988–1996. J Infect Dis. 1998;178:752–9.PubMedCrossRef Shapiro RL, Altekruse S, Hutwagner L, the Vibrio Working Group, et al. The role of gulf coast oysters harvested in warmer months in Vibrio vulnificus infections in the United States, 1988–1996. J Infect Dis. 1998;178:752–9.PubMedCrossRef
27.
Zurück zum Zitat Kuo Y-L, Shieh S-J, Chiu H-Y, Lee J-W. Necrotizing fasciitis caused by Vibrio vulnificus: epidemiology, clinical findings, treatment and prevention. Eur J Clin Microbiol Infect Dis. 2007;26:785–92.PubMedCrossRef Kuo Y-L, Shieh S-J, Chiu H-Y, Lee J-W. Necrotizing fasciitis caused by Vibrio vulnificus: epidemiology, clinical findings, treatment and prevention. Eur J Clin Microbiol Infect Dis. 2007;26:785–92.PubMedCrossRef
28.
Zurück zum Zitat Hsueh P-R, Lin C-Y, Tang H-J, et al. Vibrio vulnificus in Taiwan. Emerg Infect Dis. 2004;10:1363–8.PubMed Hsueh P-R, Lin C-Y, Tang H-J, et al. Vibrio vulnificus in Taiwan. Emerg Infect Dis. 2004;10:1363–8.PubMed
29.
Zurück zum Zitat Forbes BA, Sahm DF, Weissfeld AS. Vibrio, Aeromonas, Pleisiomonas, Shigelloides, and Chromobacterium violaceum. In: Forbes BA, Sahm DF, Weissfeld AS, editors. Bailey & Scott’s diagnostic microbiology. 11th ed. St. Louis: Mosby, Inc.; 2002. p. 423–33. Forbes BA, Sahm DF, Weissfeld AS. Vibrio, Aeromonas, Pleisiomonas, Shigelloides, and Chromobacterium violaceum. In: Forbes BA, Sahm DF, Weissfeld AS, editors. Bailey & Scott’s diagnostic microbiology. 11th ed. St. Louis: Mosby, Inc.; 2002. p. 423–33.
30.
Zurück zum Zitat Muldrew KL, Simpson JF, Stratton CW, Tang YW. Molecular diagnosis of necrotizing fasciitis by 16S rRNA gene sequencing and superantigen gene detection. J Mol Diagn. 2005;7:641–5.PubMedCrossRef Muldrew KL, Simpson JF, Stratton CW, Tang YW. Molecular diagnosis of necrotizing fasciitis by 16S rRNA gene sequencing and superantigen gene detection. J Mol Diagn. 2005;7:641–5.PubMedCrossRef
31.
Zurück zum Zitat Lee C-H, Wang C-C, Yue C-T et al. Necrotizing fasciitis caused by Vibrio vulnificus in a man with cirrhosis. Lancet Infect Dis. 2008;399. Lee C-H, Wang C-C, Yue C-T et al. Necrotizing fasciitis caused by Vibrio vulnificus in a man with cirrhosis. Lancet Infect Dis. 2008;399.
32.
Zurück zum Zitat Chuang Y-C, Liu J-W, Ko W-C, et al. In vitro synergism between cefotaxime and minocycline against Vibrio vulnificus. Antimicrob Agents Chemother. 1997;41:2214–7.PubMed Chuang Y-C, Liu J-W, Ko W-C, et al. In vitro synergism between cefotaxime and minocycline against Vibrio vulnificus. Antimicrob Agents Chemother. 1997;41:2214–7.PubMed
33.
Zurück zum Zitat Tang H-J, Chang M-C, Ko W-C, et al. In vitro and in vivo activities of newer fluoroquinolones against Vibrio vulnificus. Antimicrob Agents Chemother. 2002;46:3580–4.PubMedCrossRef Tang H-J, Chang M-C, Ko W-C, et al. In vitro and in vivo activities of newer fluoroquinolones against Vibrio vulnificus. Antimicrob Agents Chemother. 2002;46:3580–4.PubMedCrossRef
34.
Zurück zum Zitat Chuang Y-C, Ko W-C, Wang S-T, et al. Minocycline and cefotaxime in the treatment of experimental murine Vibrio vulnificus infection. Antimicrob Agents Chemother. 1998;42:1319–22.PubMed Chuang Y-C, Ko W-C, Wang S-T, et al. Minocycline and cefotaxime in the treatment of experimental murine Vibrio vulnificus infection. Antimicrob Agents Chemother. 1998;42:1319–22.PubMed
35.
Zurück zum Zitat The Sandford guide to antimicrobial therapy. In: Gilbert DN, Moellering RC, Eliopoulos GM, Chambers HF, Saag MS, editors. 40th ed; 2010. p. 51. The Sandford guide to antimicrobial therapy. In: Gilbert DN, Moellering RC, Eliopoulos GM, Chambers HF, Saag MS, editors. 40th ed; 2010. p. 51.
36.
Zurück zum Zitat Jones BL, Wilcox MH. Aeromonas infections and their treatment. J Clin Microbiol. 1995;35:453–61. Jones BL, Wilcox MH. Aeromonas infections and their treatment. J Clin Microbiol. 1995;35:453–61.
37.
Zurück zum Zitat Tsai Y-H, Hsu RW-W, Huang T-J, et al. Necrotizing soft-tissue infections and sepsis caused by Vibrio vulnificus compared with those caused by Aeromonas species. J Bone Joint Surg Am. 2007;89:631–6.PubMedCrossRef Tsai Y-H, Hsu RW-W, Huang T-J, et al. Necrotizing soft-tissue infections and sepsis caused by Vibrio vulnificus compared with those caused by Aeromonas species. J Bone Joint Surg Am. 2007;89:631–6.PubMedCrossRef
38.
Zurück zum Zitat Gold WL, Salit IE. Aeromonas hydrophila infections of skin and soft tissue: report of 11 cases and review. Clin Infect Dis. 1993;16:69–74.PubMedCrossRef Gold WL, Salit IE. Aeromonas hydrophila infections of skin and soft tissue: report of 11 cases and review. Clin Infect Dis. 1993;16:69–74.PubMedCrossRef
39.
Zurück zum Zitat Janda JM. Recent advances in the study of the taxonomy, pathogenicity and infectious syndromes associated with the genus aeromonas. Clin Microbiol Rev. 1991;4:397–410.PubMed Janda JM. Recent advances in the study of the taxonomy, pathogenicity and infectious syndromes associated with the genus aeromonas. Clin Microbiol Rev. 1991;4:397–410.PubMed
40.
Zurück zum Zitat Ghenghesh KS, Ahmed SF, El-Khalek RA, et al. Aeromonas-associated infections in developing countries. J Infect Developing Countries. 2008;2:81–98.CrossRef Ghenghesh KS, Ahmed SF, El-Khalek RA, et al. Aeromonas-associated infections in developing countries. J Infect Developing Countries. 2008;2:81–98.CrossRef
41.
Zurück zum Zitat Steinberg JP, Burd EM. Other gram-negative and gram-variable bacilli. Aeromonas species. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and practice of infectious diseases. 7th ed. Elsevier; 2010. pp. 3017–9. Steinberg JP, Burd EM. Other gram-negative and gram-variable bacilli. Aeromonas species. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and practice of infectious diseases. 7th ed. Elsevier; 2010. pp. 3017–9.
42.
Zurück zum Zitat •• Janda JM, Abbott SL. The genus Aeromonas: taxonomy pathogenesis and infection. Clin Microbiol Rev. 2010;23:35–73. This is the more recent and thorough review on Aeromonas infection. PubMedCrossRef •• Janda JM, Abbott SL. The genus Aeromonas: taxonomy pathogenesis and infection. Clin Microbiol Rev. 2010;23:35–73. This is the more recent and thorough review on Aeromonas infection. PubMedCrossRef
43.
Zurück zum Zitat Lamy B, Kodjo A, Laurent F. Prospective nationwide study of Aeromonas infections in France. J Clin Microbiol. 2009;47:1234–7.PubMedCrossRef Lamy B, Kodjo A, Laurent F. Prospective nationwide study of Aeromonas infections in France. J Clin Microbiol. 2009;47:1234–7.PubMedCrossRef
44.
Zurück zum Zitat Davis II WA, Kane JG, Garagusi VF. Human Aeromonas infections. A review of the literature and a case report of endocarditis. Medicine. 1978;57:267–77.PubMedCrossRef Davis II WA, Kane JG, Garagusi VF. Human Aeromonas infections. A review of the literature and a case report of endocarditis. Medicine. 1978;57:267–77.PubMedCrossRef
45.
Zurück zum Zitat Harris RL, Fainstein V, Elting L, et al. Bacteremia caused by Aeromonas species in hospitalized cancer patients. Rev Infect Dis. 1985;7:314–20.PubMedCrossRef Harris RL, Fainstein V, Elting L, et al. Bacteremia caused by Aeromonas species in hospitalized cancer patients. Rev Infect Dis. 1985;7:314–20.PubMedCrossRef
46.
Zurück zum Zitat Martino R, Santamaria A, Pericas R, et al. Acute rhabdomyolysis and myonecrosis complicating aeromonas bacteremia in neutropenic patients with hematologic malignancies: report of two cases. Haematologica. 1997;82:692–4.PubMed Martino R, Santamaria A, Pericas R, et al. Acute rhabdomyolysis and myonecrosis complicating aeromonas bacteremia in neutropenic patients with hematologic malignancies: report of two cases. Haematologica. 1997;82:692–4.PubMed
47.
Zurück zum Zitat Hanson PG, Standridge J, Jarret F, Maki DG. Freshwater wound infection due to aeromonas hydrophila. JAMA. 1977;238:1053–4.PubMedCrossRef Hanson PG, Standridge J, Jarret F, Maki DG. Freshwater wound infection due to aeromonas hydrophila. JAMA. 1977;238:1053–4.PubMedCrossRef
48.
Zurück zum Zitat Hiransuthikul N, Tantisirivat W, Lertutsahakul K, et al. Skin and soft-tissue infections among Tsunami survivors in southern Thailand. Clin Infect Dis. 2005;41:e93–6.PubMedCrossRef Hiransuthikul N, Tantisirivat W, Lertutsahakul K, et al. Skin and soft-tissue infections among Tsunami survivors in southern Thailand. Clin Infect Dis. 2005;41:e93–6.PubMedCrossRef
49.
Zurück zum Zitat Ribeiro NFF, Heath CH, Kierath J, et al. Burn wounds infected by contaminated water: case reports, review of the literature and recommendations for treatment. Burns. 2010;36:9–22.PubMedCrossRef Ribeiro NFF, Heath CH, Kierath J, et al. Burn wounds infected by contaminated water: case reports, review of the literature and recommendations for treatment. Burns. 2010;36:9–22.PubMedCrossRef
50.
Zurück zum Zitat Tena D, Gonzales-Praetorius A, Gimeno C, et al. Rapidly progressive myonecrosis by Aeromonas veronii biotype sobria. An Med Interna. 2006;23:540–2.PubMed Tena D, Gonzales-Praetorius A, Gimeno C, et al. Rapidly progressive myonecrosis by Aeromonas veronii biotype sobria. An Med Interna. 2006;23:540–2.PubMed
51.
Zurück zum Zitat Bauters TG, Buyla FM, Verschraegen G, et al. Infection risk related to the use of medicinal leeches. Pharm World Sci. 2007;29(3):122–5.PubMedCrossRef Bauters TG, Buyla FM, Verschraegen G, et al. Infection risk related to the use of medicinal leeches. Pharm World Sci. 2007;29(3):122–5.PubMedCrossRef
52.
Zurück zum Zitat Sartor C, Limouzin-Perotti F, Legre R, et al. Nosocomial infections with Aeromonas hydrophila from leeches. Clin Infect Dis. 2002;35:e1–5.PubMedCrossRef Sartor C, Limouzin-Perotti F, Legre R, et al. Nosocomial infections with Aeromonas hydrophila from leeches. Clin Infect Dis. 2002;35:e1–5.PubMedCrossRef
53.
Zurück zum Zitat Liu BM, Chandchien CS, Chen CH, et al. Fatal aeromonas hydrophila infection of soft tissue after endoscopic injection sclerotherapy for gastric variceal bleeding. Chang Gung Med J. 2004;27(10):766–9.PubMed Liu BM, Chandchien CS, Chen CH, et al. Fatal aeromonas hydrophila infection of soft tissue after endoscopic injection sclerotherapy for gastric variceal bleeding. Chang Gung Med J. 2004;27(10):766–9.PubMed
54.
Zurück zum Zitat Derby HA, Hammer HA. Bacteriology of butter. IV. Bacteriological studies on surface taint butter. Iowa Agric Exp Station Res Bull. 1931;145:389–416. Derby HA, Hammer HA. Bacteriology of butter. IV. Bacteriological studies on surface taint butter. Iowa Agric Exp Station Res Bull. 1931;145:389–416.
55.
Zurück zum Zitat Long HF, Hammer BW. Classification of organisms important in dairy products. III. Pseudomonas putrefaciens. Iowa Agric Exp Station Res Bull. 1941;285:176–95. Long HF, Hammer BW. Classification of organisms important in dairy products. III. Pseudomonas putrefaciens. Iowa Agric Exp Station Res Bull. 1941;285:176–95.
56.
Zurück zum Zitat MacDonell MT, Colwell RR. Phylogeny of the Vibrionaceae, and recommendation for two new genera, Listonella and Shewanella. Syst Appl Microbiol. 1985;6:171–82. MacDonell MT, Colwell RR. Phylogeny of the Vibrionaceae, and recommendation for two new genera, Listonella and Shewanella. Syst Appl Microbiol. 1985;6:171–82.
57.
Zurück zum Zitat Holt HM, Gahrn-Hansen B, Bruun B. Shewanella algae and Shewanella putrefaciens: clinical and microbiological characteristics. Clin Microbiol Infect. 2005;11:347–52.PubMedCrossRef Holt HM, Gahrn-Hansen B, Bruun B. Shewanella algae and Shewanella putrefaciens: clinical and microbiological characteristics. Clin Microbiol Infect. 2005;11:347–52.PubMedCrossRef
58.
Zurück zum Zitat Kueh HC, Kutarski P, Brunton M. Contaminated marine wounds—the risk of acquiring acute bacterial infection from marine recreational beaches. J Appl Bacteriol. 1992;73:412–20.PubMed Kueh HC, Kutarski P, Brunton M. Contaminated marine wounds—the risk of acquiring acute bacterial infection from marine recreational beaches. J Appl Bacteriol. 1992;73:412–20.PubMed
59.
Zurück zum Zitat Oh HS, Kum KA, Kim EC, et al. Outbreak of Shewanella algae and Shewanella putrefaciens infections caused by a shared measuring cup in a general surgery unit in Korea. Infect Control Hosp Epidemiol. 2008;29:742–8.PubMedCrossRef Oh HS, Kum KA, Kim EC, et al. Outbreak of Shewanella algae and Shewanella putrefaciens infections caused by a shared measuring cup in a general surgery unit in Korea. Infect Control Hosp Epidemiol. 2008;29:742–8.PubMedCrossRef
60.
Zurück zum Zitat Tsai MS, You HL, Tang YF, Liu JW. Shewanella soft tissue infection: case report and literature review. Int J Infect Dis. 2008;12:e119–24.PubMedCrossRef Tsai MS, You HL, Tang YF, Liu JW. Shewanella soft tissue infection: case report and literature review. Int J Infect Dis. 2008;12:e119–24.PubMedCrossRef
61.
Zurück zum Zitat Tsai TH, You HY. Nectotyzing fasciitis caused by shewanella putrefaciens in a uremic patient. J Microbiol Immunol Infect. 2006;39:516–8.PubMed Tsai TH, You HY. Nectotyzing fasciitis caused by shewanella putrefaciens in a uremic patient. J Microbiol Immunol Infect. 2006;39:516–8.PubMed
62.
Zurück zum Zitat Sharma KK, Kalawat U. Emerging infections: Shewanella—a series of five cases. J Lab Physicians. 2010;2:61–5.PubMedCrossRef Sharma KK, Kalawat U. Emerging infections: Shewanella—a series of five cases. J Lab Physicians. 2010;2:61–5.PubMedCrossRef
63.
Zurück zum Zitat Chen Y, Liu Y, Yen M, et al. Skin and soft-tissue manifestations of Shewanella putrfaciens infection. Clin Infect Dis. 1997;25:225–9.PubMedCrossRef Chen Y, Liu Y, Yen M, et al. Skin and soft-tissue manifestations of Shewanella putrfaciens infection. Clin Infect Dis. 1997;25:225–9.PubMedCrossRef
64.
Zurück zum Zitat Pagani L, Lang A, Vedovelli C, et al. Soft tissue infecctions and bacteremia caused by Shewanella putrefaciens. J Clin Microbiol. 2003;41(5):2240–1.PubMedCrossRef Pagani L, Lang A, Vedovelli C, et al. Soft tissue infecctions and bacteremia caused by Shewanella putrefaciens. J Clin Microbiol. 2003;41(5):2240–1.PubMedCrossRef
65.
Zurück zum Zitat Botelho-Nevers E, Gouriet F, Rovery C, et al. First case of osteomyelitis due to Shewanella algae. J Clin Microbiol. 2005;43(10):5388–90.PubMedCrossRef Botelho-Nevers E, Gouriet F, Rovery C, et al. First case of osteomyelitis due to Shewanella algae. J Clin Microbiol. 2005;43(10):5388–90.PubMedCrossRef
66.
Zurück zum Zitat Ternavasio-de-la-Vega HG, Angel-Moreno A, Hernández-Cabrera M, et al. Skin and soft tissue infections (patera foot) in immigrants, Spain. Emerg Infect Dis. 2009;15(4):598–600.PubMedCrossRef Ternavasio-de-la-Vega HG, Angel-Moreno A, Hernández-Cabrera M, et al. Skin and soft tissue infections (patera foot) in immigrants, Spain. Emerg Infect Dis. 2009;15(4):598–600.PubMedCrossRef
67.
Zurück zum Zitat Bring IJ, van Staten A, van Rensburg AJ. Shewanella (pseudomonas) putrefaciens bacteremia. Clin Infect Dis. 1995;20:1327–32.CrossRef Bring IJ, van Staten A, van Rensburg AJ. Shewanella (pseudomonas) putrefaciens bacteremia. Clin Infect Dis. 1995;20:1327–32.CrossRef
68.
Zurück zum Zitat Appelbaum PC, Bowen AJ. Opportunistic infection of chronic skin ulcers with Pseudomonas putrefaciens. Br J Dermatol. 1978;98:229–31.PubMedCrossRef Appelbaum PC, Bowen AJ. Opportunistic infection of chronic skin ulcers with Pseudomonas putrefaciens. Br J Dermatol. 1978;98:229–31.PubMedCrossRef
69.
Zurück zum Zitat Domínguez H, Vogel BF, Gram L, et al. Shewanella alga bacteremia in two patients with lower leg ulcers. Clin Infect Dis. 1996;22:1036–9.PubMedCrossRef Domínguez H, Vogel BF, Gram L, et al. Shewanella alga bacteremia in two patients with lower leg ulcers. Clin Infect Dis. 1996;22:1036–9.PubMedCrossRef
70.
Zurück zum Zitat Kim JH, Cooper RA, Welty WK, et al. Pseudomonas putrefaciens bacteremia. Rev Infect Dis. 1989;11:97–104.PubMedCrossRef Kim JH, Cooper RA, Welty WK, et al. Pseudomonas putrefaciens bacteremia. Rev Infect Dis. 1989;11:97–104.PubMedCrossRef
71.
Zurück zum Zitat Pope TL, Teague WG, Kossack R, et al. Pseudomonas sacroiliac osteomyelitis: diagnosis by gallium citrate Ga 67 scan. Am J Dis Child. 1982;136(7):649–50.PubMed Pope TL, Teague WG, Kossack R, et al. Pseudomonas sacroiliac osteomyelitis: diagnosis by gallium citrate Ga 67 scan. Am J Dis Child. 1982;136(7):649–50.PubMed
72.
Zurück zum Zitat Levy PY, Tessier JL. Arthritis due to Shewanella purtrefaciens. Clin Infect Dis. 1998;26:536.PubMedCrossRef Levy PY, Tessier JL. Arthritis due to Shewanella purtrefaciens. Clin Infect Dis. 1998;26:536.PubMedCrossRef
73.
Zurück zum Zitat Laudat P, Audurier A, Loulergue F, et al. Pseudomonas putrefaciens meningitis. J Infect. 1983;7(3):281–3.PubMedCrossRef Laudat P, Audurier A, Loulergue F, et al. Pseudomonas putrefaciens meningitis. J Infect. 1983;7(3):281–3.PubMedCrossRef
74.
Zurück zum Zitat 'Süzük S, Yetener V, Ergüngör F, Balaban N. Cerebellar abscess caused by Shewanella putrefaciens. Scand J Infect Dis. 2004;36(8):621–2.PubMedCrossRef 'Süzük S, Yetener V, Ergüngör F, Balaban N. Cerebellar abscess caused by Shewanella putrefaciens. Scand J Infect Dis. 2004;36(8):621–2.PubMedCrossRef
75.
Zurück zum Zitat Dhawan B, Chaudhry R, Mishra BM, Agarwal R. Isolation of Shwanella purtrefaciens from a rheumatic heart disease patient with infective endocarditis. J Clin Microbiol. 1998;36:2394.PubMed Dhawan B, Chaudhry R, Mishra BM, Agarwal R. Isolation of Shwanella purtrefaciens from a rheumatic heart disease patient with infective endocarditis. J Clin Microbiol. 1998;36:2394.PubMed
76.
Zurück zum Zitat Butt AA, Figueroa J, Martin DH. Ocular infection caused by three unusual marine organisms. Clin Infect Dis. 1997;24:740.PubMedCrossRef Butt AA, Figueroa J, Martin DH. Ocular infection caused by three unusual marine organisms. Clin Infect Dis. 1997;24:740.PubMedCrossRef
77.
Zurück zum Zitat Kueh HC, Kutarski P, Brunton M. Contaminated marine wounds-the risk of acquiring acute bacterial infection from marine recreational beaches. J Appl Bacteriol. 1992;73:412–20.PubMed Kueh HC, Kutarski P, Brunton M. Contaminated marine wounds-the risk of acquiring acute bacterial infection from marine recreational beaches. J Appl Bacteriol. 1992;73:412–20.PubMed
78.
Zurück zum Zitat Roger SD, Chen SC, Lawrence S, Sorrell TC. Pseudomonas purtrefaciens bacteremia in a peritoneal dialysis patient. Nephrol Dial Transplant. 1991;6:73.PubMed Roger SD, Chen SC, Lawrence S, Sorrell TC. Pseudomonas purtrefaciens bacteremia in a peritoneal dialysis patient. Nephrol Dial Transplant. 1991;6:73.PubMed
79.
Zurück zum Zitat Chen SC, Lawrence RH, Packham DR, Sorell TC. Cellulitis due to pseudomonas purtrefaciens: possible production of exotoxins. Rev Infect Dis. 1991;13(4):642–3.PubMedCrossRef Chen SC, Lawrence RH, Packham DR, Sorell TC. Cellulitis due to pseudomonas purtrefaciens: possible production of exotoxins. Rev Infect Dis. 1991;13(4):642–3.PubMedCrossRef
80.
Zurück zum Zitat Holt HM, Gahrn-Hansen B, Braun B. Shewanella species: infections in Denmark and phenotypic characterization. Clin Microbiol Infect. 2004;20 suppl 3:343–9. Holt HM, Gahrn-Hansen B, Braun B. Shewanella species: infections in Denmark and phenotypic characterization. Clin Microbiol Infect. 2004;20 suppl 3:343–9.
81.
Zurück zum Zitat Griffith DE, Aksamit T, Brown-Elliott BA, et al. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med. 2007;175:367–416.PubMedCrossRef Griffith DE, Aksamit T, Brown-Elliott BA, et al. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med. 2007;175:367–416.PubMedCrossRef
82.
Zurück zum Zitat Piersimoni C, Scarparo C. Extrapulmonary infections associated with nontuberculous mycobacteria in immunocompetent persons. Emerg Infect Dis. 2009;15:1351–8.PubMedCrossRef Piersimoni C, Scarparo C. Extrapulmonary infections associated with nontuberculous mycobacteria in immunocompetent persons. Emerg Infect Dis. 2009;15:1351–8.PubMedCrossRef
83.
Zurück zum Zitat Falkinham JO. Epidemiology of infection by nontuberculosis mycobacteria. Clin Microbiol Rev. 1996;9:177–215.PubMed Falkinham JO. Epidemiology of infection by nontuberculosis mycobacteria. Clin Microbiol Rev. 1996;9:177–215.PubMed
84.
Zurück zum Zitat Wagner D, Young LS. Nontuberculous mycobacterial infections: a clinical review. Infection. 2004;32:257–70.PubMedCrossRef Wagner D, Young LS. Nontuberculous mycobacterial infections: a clinical review. Infection. 2004;32:257–70.PubMedCrossRef
85.
Zurück zum Zitat Aubry A, Chosidow O, Caumes E, et al. Sixty-three cases of Mycobacterium marinum infection: clinical features, treatment, and antibiotic susceptibility of causative isolates. Arch Intern Med. 2002;162(15):1746–52.PubMedCrossRef Aubry A, Chosidow O, Caumes E, et al. Sixty-three cases of Mycobacterium marinum infection: clinical features, treatment, and antibiotic susceptibility of causative isolates. Arch Intern Med. 2002;162(15):1746–52.PubMedCrossRef
87.
Zurück zum Zitat Danko JR, Gilliland WR, Miller RS, Decker CF. Disseminated Mycobacterium marinum infection in a patient with rheumatoid arthritis receiving infliximab therapy. Scand J Infect Dis. 2009;41:252–5.PubMedCrossRef Danko JR, Gilliland WR, Miller RS, Decker CF. Disseminated Mycobacterium marinum infection in a patient with rheumatoid arthritis receiving infliximab therapy. Scand J Infect Dis. 2009;41:252–5.PubMedCrossRef
88.
Zurück zum Zitat Imakado S, Kojima Y, Hiyoshi T, Morimoto S. Disseminated Mycobacterium marinum infection in a patient with diabetic nephropathy. Diabetes Res Clin Pract. 2009;83(2):e35–6.PubMedCrossRef Imakado S, Kojima Y, Hiyoshi T, Morimoto S. Disseminated Mycobacterium marinum infection in a patient with diabetic nephropathy. Diabetes Res Clin Pract. 2009;83(2):e35–6.PubMedCrossRef
89.
Zurück zum Zitat Casal M, Casal MM, Spanish Group of Mycobacteriology. Multicenter study of incidence of Mycobacterium marinum in humans in Spain. Int J Tuberc Lung Dis. 2001;5:197–9.PubMed Casal M, Casal MM, Spanish Group of Mycobacteriology. Multicenter study of incidence of Mycobacterium marinum in humans in Spain. Int J Tuberc Lung Dis. 2001;5:197–9.PubMed
90.
Zurück zum Zitat Liao CH, Lai CC, Ding LW, et al. Skin and soft tissue infection caused by non-tuberculous mycobacteria. Int J Tuberc Lung Dis. 2007;11(1):96–102.PubMed Liao CH, Lai CC, Ding LW, et al. Skin and soft tissue infection caused by non-tuberculous mycobacteria. Int J Tuberc Lung Dis. 2007;11(1):96–102.PubMed
91.
Zurück zum Zitat Chen HY, Chen CY, Huang CT, et al. Skin and soft-tissue infection caused by non-tuberculous mycobacteria in Taiwan, 1997–2008. Epidemiol Infect. 2011;139(1):121–9.PubMedCrossRef Chen HY, Chen CY, Huang CT, et al. Skin and soft-tissue infection caused by non-tuberculous mycobacteria in Taiwan, 1997–2008. Epidemiol Infect. 2011;139(1):121–9.PubMedCrossRef
92.
Zurück zum Zitat Agnew W, Barnes AC. Streptococcus iniae: An aquatic pathogen of global veterinary significance and a challenging candidate for reliable vaccination. Vet Microbiol. 2007;122:1–15.PubMedCrossRef Agnew W, Barnes AC. Streptococcus iniae: An aquatic pathogen of global veterinary significance and a challenging candidate for reliable vaccination. Vet Microbiol. 2007;122:1–15.PubMedCrossRef
93.
Zurück zum Zitat Peir GB, Madin SH. Streptococcus iniae sp. nov., a betahemolytic streptococcus isolated from an Amazon freshwater dolphin, Inia geoffrensis. Int J Syst Bacteriol. 1976;26:545–53.CrossRef Peir GB, Madin SH. Streptococcus iniae sp. nov., a betahemolytic streptococcus isolated from an Amazon freshwater dolphin, Inia geoffrensis. Int J Syst Bacteriol. 1976;26:545–53.CrossRef
94.
Zurück zum Zitat Weinstein MR, Litt M, Kertesz DA, et al. Invasive infections due to a fish pathogen, Streptococcus iniae. S.iniae study group. N Engl J Med. 1997;337:589–94.PubMedCrossRef Weinstein MR, Litt M, Kertesz DA, et al. Invasive infections due to a fish pathogen, Streptococcus iniae. S.iniae study group. N Engl J Med. 1997;337:589–94.PubMedCrossRef
95.
Zurück zum Zitat Hansen GR, Woodall J, Brown C, et al. Emerging zoonotic diseases. Panel summary from the International Conference on Emerging Infectious Diseases Conference, Atlanta, Georgia, 2000. Emerg Infect Dis. 2001;7:537.PubMedCrossRef Hansen GR, Woodall J, Brown C, et al. Emerging zoonotic diseases. Panel summary from the International Conference on Emerging Infectious Diseases Conference, Atlanta, Georgia, 2000. Emerg Infect Dis. 2001;7:537.PubMedCrossRef
96.
Zurück zum Zitat Sun J-R, Yan J-C, Yeh C-Y, et al. Invasive infection with Streptococcus iniae in Taiwan. J Med Microbiol. 2007;56:1246–9.PubMedCrossRef Sun J-R, Yan J-C, Yeh C-Y, et al. Invasive infection with Streptococcus iniae in Taiwan. J Med Microbiol. 2007;56:1246–9.PubMedCrossRef
97.
Zurück zum Zitat Koh TH, Sng LH, Yuen SM, et al. Streptococcal cellulitis following preparation of fresh raw seafood. Zoonoses Public Health. 2009;56:206–8.PubMedCrossRef Koh TH, Sng LH, Yuen SM, et al. Streptococcal cellulitis following preparation of fresh raw seafood. Zoonoses Public Health. 2009;56:206–8.PubMedCrossRef
98.
Zurück zum Zitat Lau SKP, Woo PCY, Tse H, et al. Invasive Streptococcus iniae infections outside North America. J Clin Microbiol. 2003;41:1004–9.PubMedCrossRef Lau SKP, Woo PCY, Tse H, et al. Invasive Streptococcus iniae infections outside North America. J Clin Microbiol. 2003;41:1004–9.PubMedCrossRef
99.
Zurück zum Zitat Facklam R, Elliott J, Shewmaker L, Reingold A. Identification and characterization of sporadic isolates of Streptococcus iniae isolated from humans. J Clin Microbiol. 2005;43:933–7.PubMedCrossRef Facklam R, Elliott J, Shewmaker L, Reingold A. Identification and characterization of sporadic isolates of Streptococcus iniae isolated from humans. J Clin Microbiol. 2005;43:933–7.PubMedCrossRef
100.
Zurück zum Zitat Fuller JD, Bast DJ, Nizet V, et al. Streptococcus iniae virulence is associated with a distinct genetic profile. Infect Immun. 2001;69:1994–2000.PubMedCrossRef Fuller JD, Bast DJ, Nizet V, et al. Streptococcus iniae virulence is associated with a distinct genetic profile. Infect Immun. 2001;69:1994–2000.PubMedCrossRef
101.
Zurück zum Zitat Reboli AC. Erysipelothrix rhusiopathiae. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and practice of infectious diseases. 7th ed. Elsevier; 2010. pp. 2733–5. Reboli AC. Erysipelothrix rhusiopathiae. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and practice of infectious diseases. 7th ed. Elsevier; 2010. pp. 2733–5.
102.
Zurück zum Zitat Wood RL. Erysipelothrix infection. In: Hubbert WT, McCullough WF, Schnurrenberger PR, editors. Diseases transmitted from animals to man. 6th ed. Springfield: Thomas; 1975. p. 271–81. Wood RL. Erysipelothrix infection. In: Hubbert WT, McCullough WF, Schnurrenberger PR, editors. Diseases transmitted from animals to man. 6th ed. Springfield: Thomas; 1975. p. 271–81.
103.
Zurück zum Zitat • Tlougan BE, Podjasel JO, Adams BB. Aquatic sport dermatoses: part 3 on the water. Int J Dermatol. 2010;49:1111–20. This is one of a three-part comprehensive series on water-related dermatologic conditions seen in people participating in aquatic activities. PubMedCrossRef • Tlougan BE, Podjasel JO, Adams BB. Aquatic sport dermatoses: part 3 on the water. Int J Dermatol. 2010;49:1111–20. This is one of a three-part comprehensive series on water-related dermatologic conditions seen in people participating in aquatic activities. PubMedCrossRef
104.
Zurück zum Zitat Nelson E. Five hundred cases of erysipeloid. Rocky Mtn Med J. 1955;52:40–2. Nelson E. Five hundred cases of erysipeloid. Rocky Mtn Med J. 1955;52:40–2.
105.
Zurück zum Zitat Collier DN. Cutaneous infections from coastal and marine bacteria. Dermatol Ther. 2002;15:1–9.CrossRef Collier DN. Cutaneous infections from coastal and marine bacteria. Dermatol Ther. 2002;15:1–9.CrossRef
106.
107.
Zurück zum Zitat Hocqueloux L, Poisson DM, Sunder S, et al. Septic arthritis caused by Erysipelothrix rhusiopathiae in a prosthetic knee joint. J Clin Microbiol. 2010;48:333–5.PubMedCrossRef Hocqueloux L, Poisson DM, Sunder S, et al. Septic arthritis caused by Erysipelothrix rhusiopathiae in a prosthetic knee joint. J Clin Microbiol. 2010;48:333–5.PubMedCrossRef
108.
Zurück zum Zitat Brooke CJ, Riley TV. Erysipelothrix rhusiopathiae: bacteriology, epidemiology and clinical manifestations of an occupational pathogen. J Med Microbiol. 1999;48:789–99.PubMedCrossRef Brooke CJ, Riley TV. Erysipelothrix rhusiopathiae: bacteriology, epidemiology and clinical manifestations of an occupational pathogen. J Med Microbiol. 1999;48:789–99.PubMedCrossRef
109.
Zurück zum Zitat Fidalgo SG, Riley TV. Detection of Erypelothrix rhusiopatieae in clinical and environmental samples. Methods Mol Biol. 2004;268:199–205.PubMed Fidalgo SG, Riley TV. Detection of Erypelothrix rhusiopatieae in clinical and environmental samples. Methods Mol Biol. 2004;268:199–205.PubMed
110.
Zurück zum Zitat Reboli AC, Farrar WE. The genus Erysipelothrix. In: Balows A, Truper HG, Dworkin M, Harder W, Schleifer K, editors. The Prokaryotes. A handbook on the biology of bacteria: ecophysiology, isolation, identification, applications. New York: Springer; 1992. p. 1629–42. Reboli AC, Farrar WE. The genus Erysipelothrix. In: Balows A, Truper HG, Dworkin M, Harder W, Schleifer K, editors. The Prokaryotes. A handbook on the biology of bacteria: ecophysiology, isolation, identification, applications. New York: Springer; 1992. p. 1629–42.
Metadaten
Titel
Soft Tissue Infections Caused by Marine Bacterial Pathogens: Epidemiology, Diagnosis, and Management
verfasst von
Renato Finkelstein
Ilana Oren
Publikationsdatum
01.10.2011
Verlag
Current Science Inc.
Erschienen in
Current Infectious Disease Reports / Ausgabe 5/2011
Print ISSN: 1523-3847
Elektronische ISSN: 1534-3146
DOI
https://doi.org/10.1007/s11908-011-0199-3

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