nach oben

Lasers in Medical Science

Erschienen in:

01.12.2024 | Review Article

A systematic review and meta-analysis of randomized controlled trials on the effectiveness of high-intensity laser therapy in the management of neck pain

verfasst von: Hernán Andrés de la Barra Ortiz, Mariana Arias, Richard Eloin Liebano

Erschienen in: Lasers in Medical Science | Ausgabe 1/2024

Einloggen, um Zugang zu erhalten

Abstract

The purpose of this systematic review was to evaluate the effects of high-intensity laser therapy (HILT) on pain, disability, and range of movement in patients with neck pain. Randomized controlled trials (RCTs) of HILT for neck pain disorders were searched across databases such as PubMed, Web of Science, Scopus, CINAHL, Science Direct, Cochrane Library, the PEDro database, and Google Scholar (updated January 7, 2024). The main outcome was pain intensity, with neck disability and cervical range of motion as secondary outcomes. Researchers reviewed article titles and abstracts from different databases using the Rayyan web app. Study quality was assessed using the Cochrane risk of bias tool, and evidence-based recommendations were developed using the GRADE approach. A meta-analysis was conducted to calculate the pooled effect in terms of mean differences (MD) for the outcomes of interest, along with a 95% confidence interval (95% CI). Twenty studies met the selection criteria and were potentially eligible for inclusion in the meta-analysis. At the end of the treatment, there was a statistically significant (p < 0.01) pooled MD of -14.1 mm for pain intensity (17 RCTs) with the VAS (95% CI:-18.4,-9.7), 3.9° (95% CI:1.9,6.7) for cervical extension (9 RCTs), and -8.3% (95% CI:-14.1,-4.1) for disability diminish (12 RCTs) with the neck disability index in favor of HILT. Only the results for pain intensity are in line with the minimal clinically important differences (MCID) reported in the literature. Overall, the evidence was deemed significant but with low certainty, attributed to observed heterogeneity and some risk of bias among the RCTs. HILT demonstrates effectiveness in reducing neck pain and disability while enhancing cervical extension when added to other physical therapy interventions, especially therapeutic exercise, based on a moderate level of evidence. This review highlights that the most favorable results are obtained when HILT is employed to address myofascial pain, cervical radiculopathy and chronic neck pain.

PROSPERO registration number: CRD42023387394 (Registration date, 14/01/2023).

Cohen SP (2015) Epidemiology, diagnosis, and treatment of neck pain. Mayo Clin Proc 90(2):284–299. https://doi.org/10.1016/j.mayocp.2014.09.008CrossRefPubMed

Kazeminasab S, Nejadghaderi SA, Amiri P, Pourfathi H, Araj-Khodaei M, Sullman MJM et al (2022) Neck pain: global epidemiology, trends and risk factors. BMC Musculoskelet Disord 23(1):26CrossRefPubMedPubMedCentral

Cohen SP, Hooten WM (2017) Advances in the diagnosis and management of neck pain. BMJ 14(358):j3221. https://doi.org/10.1136/bmj.j3221CrossRef

Popescu A, Lee H (2020) Neck pain and lower back pain. Med Clin North Am 104(2):279–292. https://doi.org/10.1016/j.mcna.2019.11.003CrossRefPubMed

Fejer R, Hartvigsen J (2008) Neck pain and disability due to neck pain: what is the relation? Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc 17(1):80–88. https://doi.org/10.1007/s00586-007-0521-9CrossRef

Price J, Rushton A, Tyros I, Tyros V, Heneghan NR (2020) Effectiveness and optimal dosage of exercise training for chronic non-specific neck pain: A systematic review with a narrative synthesis. PLoS ONE 15(6):e0234511. https://doi.org/10.1371/journal.pone.0234511CrossRefPubMedPubMedCentral

Lew J, Kim J, Nair P (2021) Comparison of dry needling and trigger point manual therapy in patients with neck and upper back myofascial pain syndrome: a systematic review and meta-analysis. J Man Manip Ther 29(3):136–146. https://doi.org/10.1080/10669817.2020.1822618CrossRefPubMed

Kroeling P, Gross A, Graham N, Burnie SJ, Szeto G, Goldsmith CH et al (2013) Electrotherapy for neck pain. Cochrane Database Syst Rev 26(8):CD004251. https://doi.org/10.1002/14651858.CD004251.pub5CrossRef

Chow RT, Johnson MI, Lopes-Martins RAB, Bjordal JM (2009) Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials. Lancet Lond Engl 374(9705):1897–1908. https://doi.org/10.1016/S0140-6736(09)61522-1CrossRef

10.

Gross AR, Dziengo S, Boers O, Goldsmith CH, Graham N, Lilge L et al (2013) Low-Level Laser Therapy (LLLT) for Neck Pain: A Systematic Review and Meta-Regression. Open Orthop J 7:396–419. https://doi.org/10.2174/1874325001307010396CrossRefPubMedPubMedCentral

11.

Cai P, Wei X, Wang W, Cai C, Li H (2023) High-intensity laser therapy on pain relief in symptomatic knee osteoarthritis: a systematic review and meta-analysis. J Back Musculoskelet Rehabil 36(5):1011–1021. https://doi.org/10.3233/BMR-220228CrossRefPubMed

12.

Arroyo-Fernández R, Aceituno-Gómez J, Serrano-Muñoz D, Avendaño-Coy J (2023) High-Intensity Laser Therapy for Musculoskeletal Disorders: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. J Clin Med 12(4):1479. https://doi.org/10.3390/jcm12041479CrossRefPubMedPubMedCentral

13.

de la Ortiz HA, B, Cangas SA, Herrera AC, García FO, Velásquez SV (2021) Efficacy of class IV laser in the management of musculoskeletal pain: a systematic review. Physiother Q 29(2):1–11. https://doi.org/10.5114/pq.2021.105882

14.

Stasinopoulos D, Giannakou K, Lamnisos D (2021) The effectiveness of high intensity laser therapy (HILT) in the treatment of lateral elbow tendinopathy: a systematic review. J Laser Opt Photonics 08:194. https://doi.org/10.4172/2469-410X.1000194CrossRef

15.

Dundar U, Turkmen U, Toktas H, Solak O, Ulasli AM (2015) Effect of high-intensity laser therapy in the management of myofascial pain syndrome of the trapezius: a double-blind, placebo-controlled study. Lasers Med Sci 30(1):325–332. https://doi.org/10.1007/s10103-014-1671-8CrossRefPubMed

16.

Alayat MS, Elsodany AM, Miyajan AF, Alzhrani AA, Alzhrani HMS, Maqliyah AM (2019) Changes in local skin temperature after the application of a pulsed Nd:YAG laser to healthy subjects: a prospective crossover controlled trial. Lasers Med Sci 34(8):1681–1688. https://doi.org/10.1007/s10103-019-02769-6CrossRefPubMed

17.

Starzec-Proserpio M, Grigol Bardin M, Fradette J, Tu LM, Bérubè-Lauzière Y, Paré J et al (2022) High-intensity laser therapy (HILT) as an emerging treatment for vulvodynia and chronic musculoskeletal pain disorders: A systematic review of treatment efficacy. J Clin Med 11(13):3701. https://doi.org/10.3390/jcm11133701CrossRefPubMedPubMedCentral

18.

Ordahan B, Yigit F, Mülkoglu C (2023) Efficacy of low-level laser versus high-intensity laser therapy in the management of adhesive capsulitis: A randomized clinical trial. Saudi J Med Med Sci 11(3):201–207. https://doi.org/10.4103/sjmms.sjmms_626_22CrossRefPubMedPubMedCentral

19.

de la Barra HA, Parizotto N, Arias M, Liebano R (2023) Effectiveness of high-intensity laser therapy in the treatment of patients with frozen shoulder: a systematic review and meta-analysis. Lasers Med Sci 38(1):266–273. https://doi.org/10.1007/s10103-023-03901-3CrossRef

20.

Page MJ, Moher D, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD et al (2021) PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. BMJ 29(372):n160. https://doi.org/10.1136/bmj.n160CrossRef

21.

Sideri S, Papageorgiou SN, Eliades T (2018) Registration in the international prospective register of systematic reviews (PROSPERO) of systematic review protocols was associated with increased review quality. J Clin Epidemiol 100:103–110. https://doi.org/10.1016/j.jclinepi.2018.01.003CrossRefPubMed

22.

Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A (2016) Rayyan-a web and mobile app for systematic reviews. Syst Rev 5(1):210. https://doi.org/10.1186/s13643-016-0384-4CrossRefPubMedPubMedCentral

23.

Jørgensen L, Paludan-Müller AS, Laursen DRT, Savović J, Boutron I, Sterne JAC et al (2016) Evaluation of the Cochrane tool for assessing risk of bias in randomized clinical trials: overview of published comments and analysis of user practice in Cochrane and non-Cochrane reviews. Syst Rev 10(5):80. https://doi.org/10.1186/s13643-016-0259-8CrossRef

24.

Kamper SJ (2020) Risk of bias and study quality assessment: Linking evidence to practice. J Orthop Sports Phys Ther 50(5):277–9. https://doi.org/10.2519/jospt.2020.0702CrossRefPubMed

25.

McHugh ML (2012) Interrater reliability: the kappa statistic. Biochem Medica 22(3):276–82. https://doi.org/10.11613/bm.2012.031CrossRef

26.

Ioannidis JPA (2008) Interpretation of tests of heterogeneity and bias in meta-analysis. J Eval Clin Pract 14(5):951–957. https://doi.org/10.1111/j.1365-2753.2008.00986.xCrossRefPubMed

27.

Austin TM, Richter RR, Sebelski CA (2014) Introduction to the GRADE approach for guideline development: considerations for physical therapist practice. Phys Ther. 94(11):1652–9. https://doi.org/10.2522/ptj.20130627CrossRefPubMed

28.

Conforti M, Fachinetti GP (2013) High power laser therapy treatment compared to simple segmental physical rehabilitation in whiplash injuries (1° and 2° grade of the Quebec Task Force classification) involving muscles and ligaments. Muscles Ligaments Tendons J 3(2):106–11. https://doi.org/10.11138/mltj/2013.3.2.106CrossRefPubMedPubMedCentral

29.

Alayat MSM, Mohamed AA, Helal OF, Khaled OA (2016) Efficacy of high-intensity laser therapy in the treatment of chronic neck pain: a randomized double-blind placebo-control trial. Lasers Med Sci 31(4):687–694. https://doi.org/10.1007/s10103-016-1910-2CrossRefPubMed

30.

Alayat MS, Elsoudany AM, Ali ME (2017) Efficacy of multiwave locked system laser on pain and function in patients with chronic neck pain: a randomized placebo-controlled trial. Photomed Laser Surg 35(8):450–455. https://doi.org/10.1089/pho.2017.4292CrossRefPubMed

31.

Haładaj R, Pingot M, Topol M (2017) The effectiveness of cervical spondylosis therapy with saunders traction device and high-intensity laser therapy: a randomized controlled trial. Med Sci Monit Int Med J Exp Clin Res. 23:335–42. https://doi.org/10.12659/msm.899454CrossRef

32.

Venosa M, Romanini E, Padua R, Cerciello S (2019) Comparison of high-intensity laser therapy and combination of ultrasound treatment and transcutaneous nerve stimulation in patients with cervical spondylosis: a randomized controlled trial. Lasers Med Sci 34(5):947–953. https://doi.org/10.1007/s10103-018-2682-7CrossRefPubMed

33.

Yilmaz M, Tarakci D, Tarakci E (2020) Comparison of high-intensity laser therapy and combination of ultrasound treatment and transcutaneous nerve stimulation on cervical pain associated with cervical disc herniation: A randomized trial. Complement Ther Med 49:102295. https://doi.org/10.1016/j.ctim.2019.102295CrossRefPubMed

34.

Ahmed HM, Abu Taleb E, Ameen FH (2020) High intensity laser therapy on pain in patients with myofascial trigger points. Egypt J Phys Ther. 3(1):1–8. https://doi.org/10.21608/ejpt.2020.33415.1009CrossRef

35.

Alayat MS, Battecha KH, ELsodany AM, Ali MI (2020) Pulsed ND:YAG laser combined with progressive pressure release in the treatment of cervical myofascial pain syndrome: a randomized control trial. J Phys Ther Sci. 32(7):422–7. https://doi.org/10.1589/jpts.32.422CrossRefPubMedPubMedCentral

36.

Shady NAE-R, Negm HM, Zitoun ZMY, Abdelhakiem NM (2020) Multimodal intervention of high-intensity laser with neurodynamic mobilization in cervical radiculopathy. Pak J Med Amp Health Sci 14(4)

37.

Parandnia A, Yassin M, Sarrafzadeh J, Salehi R, Navaei F (2020) Comparison of the effects of dry needling and high-intensity laser therapy on pain intensity and pain pressure threshold in females with active trigger points in upper trapezius muscle: a single-blind randomized clinical trial. Funct Disabil J 3(1):111–122CrossRef

38.

Kenareh R, Mirmohammadi SJ, Khatibi A, Shamsi F, Mehrparvar AH (2021) The comparison of the efficacy of photobiomodulation and ultrasound in the treatment of chronic non-specific neck pain: a randomized single-blind controlled trial. J Lasers Med Sci. 12:e20. https://doi.org/10.34172/jlms.2021.20CrossRefPubMedPubMedCentral

39.

Barassi G, Supplizi M, Prosperi L, Irace G, Younes A, Della Rovere M et al (2021) Dual-wavelength high-power laser therapy and neuromuscular manual therapy in chronic neck pain: a randomized clinical trial. J Biol Regul Homeost Agents. 35(2):767–73. https://doi.org/10.23812/21-37-LCrossRefPubMed

40.

Taleb EA, Ahmed HM, Ameen FH, Lasheen YR, Albalawi HF, Eldesoky MT (2022) Effect of high-intensity laser on upper trapezius myofascial pain syndrome: Single-blinded randomized control trial. Int J Health Sci. 6(3):1227–39. https://doi.org/10.53730/ijhs.v6n3.11987CrossRef

41.

Ashour A (2020) A randomized comparative study between high-intensity laser therapy and ultrasound therapy on chronic neck pain among adult patients. Al-Quds University. https://dspace.alquds.edu/handle/20.500.12213/7597. Accessed 24 Jan 2024

42.

Ahi ED, Sirzai H (2022) Comparison of the effectiveness of dry needling and high-intensity laser therapy in the treatment of myofascial pain syndrome: a randomized single-blind controlled study. Lasers Med Sci 38(1):3. https://doi.org/10.1007/s10103-022-03687-wCrossRefPubMed

43.

Ince S, Eyvaz N, Dündar Ü, Toktaş H, Yeşil H, Eroglu S et al (2023) Clinical efficiency of high-intensity laser therapy in patients with cervical radiculopathy: a 12-week follow-up, randomized, placebo-controlled trial. Am J Phys Med Rehabil. https://doi.org/10.1097/PHM.0000000000002275CrossRefPubMed

44.

Tajali B, Namvar H, Olyaie G, Bagheri H, Saneie S, Hosienifar M (2023) Effects of high power laser plus manual therapy versus manual therapy alone on muscle activity in patients with chronic cervical radiculopathy. J Popl Ther Clin Pharmacol 30(1):477–489. https://jptcp.com/index.php/jptcp/article/view/2549. Accessed 24 Jan 2024

45.

Ramadan N, Gawaan A, Ali M, Gammal E, Aboelnour N (2023) Effect of pulsed high intensity laser therapy on cervical myofascial pain syndrome after neck dissection surgeries. Egyptian J Hospital Med 92(1):6217–6222CrossRef

46.

Sherif D, Elgohary A, Shendy W, Darwesh A (2023) Effect of high-power laser therapy on pain and electrophysiological study in cervical radiculopathy patients: a randomized controlled trial. Med J Cairo Univ 9(3):1147–1158

47.

Melsen WG, Bootsma MCJ, Rovers MM, Bonten MJM (2014) The effects of clinical and statistical heterogeneity on the predictive values of results from meta-analyses. Clin Microbiol Infect Off Publ Eur Soc Clin Microbiol Infect Dis 20(2):123–129. https://doi.org/10.1111/1469-0691.12494CrossRef

48.

Guyatt G, Oxman AD, Akl EA, Kunz R, Vist G, Brozek J et al (2011) GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. J Clin Epidemiol. 64(4):383–94. https://doi.org/10.1016/j.jclinepi.2010.04.026CrossRefPubMed

49.

Gallagher EJ, Liebman M, Bijur PE (2001) Prospective validation of clinically important changes in pain severity measured on a visual analog scale. Ann Emerg Med 38(6):633–638. https://doi.org/10.2174/1874325001307010396CrossRefPubMed

50.

Bird SB, Dickson EW (2001) Clinically significant changes in pain along the visual analog scale. Ann Emerg Med 38(6):639–643. https://doi.org/10.1067/mem.2001.118012CrossRefPubMed

51.

Mense S (2008) Muscle Pain: Mechanisms and Clinical Significance. Dtsch Ärztebl Int 105(12):214–219. https://doi.org/10.1016/j.ptsp.2011.11.003CrossRefPubMedPubMedCentral

52.

Louw S, Makwela S, Manas L, Meyer L, Terblanche D, Brink Y (2017) Effectiveness of exercise in office workers with neck pain: a systematic review and meta-analysis. South Afr J Physiother 73(1):392. https://doi.org/10.4102/sajp.v73i1.392CrossRef

53.

Villanueva-Ruiz I, Falla D, Lascurain-Aguirrebeña I (2022) Effectiveness of specific neck exercise for nonspecific neck pain; usefulness of strategies for patient selection and tailored exercise-a systematic review with meta-analysis. Phys Ther. 102(2):pzab259. https://doi.org/10.1093/ptj/pzab259CrossRefPubMed

54.

Jørgensen R, Ris I, Juhl C, Falla D, Juul-Kristensen B (2017) Responsiveness of clinical tests for people with neck pain. BMC Musculoskelet Disord 18(1). https://doi.org/10.1186/s12891-017-1918-1

55.

Shin HJ, Kim SH, Hahm SC, Cho HY (2020) Thermotherapy plus neck stabilization exercise for chronic nonspecific neck pain in elderly: a single-blinded randomized controlled trial. Int J Environ Res Public Health 17(15):5572. https://doi.org/10.3390/ijerph17155572CrossRefPubMedPubMedCentral

56.

Young IA, Dunning J, Butts R, Mourad F, Cleland JA (2019) Reliability, construct validity, and responsiveness of the neck disability index and numeric pain rating scale in patients with mechanical neck pain without upper extremity symptoms. Physiother Theory Pract 35(12):1328–1335. https://doi.org/10.1080/09593985.2018.1471763CrossRefPubMed

57.

Paez A (2017) Gray literature: An important resource in systematic reviews: PAEZ. J Evid Based Med. 10(3):233–40. https://doi.org/10.1111/jebm.12266CrossRefPubMed

Titel: A systematic review and meta-analysis of randomized controlled trials on the effectiveness of high-intensity laser therapy in the management of neck pain
verfasst von: Hernán Andrés de la Barra Ortiz
Mariana Arias
Richard Eloin Liebano
Publikationsdatum: 01.12.2024
Verlag: Springer London
Erschienen in: Lasers in Medical Science / Ausgabe 1/2024
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-024-04069-0

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

A systematic review and meta-analysis of randomized controlled trials on the effectiveness of high-intensity laser therapy in the management of neck pain

Abstract

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 1/2024

Characterizing colon cancer stages through optical polarimetry-assisted digital staining

Association of Papacarie Duo® and low-level laser in antimicrobial photodynamic therapy (aPDT)

An evaluation of photobiomodulation effects on human gingival fibroblast cells under hyperglycemic condition: an in vitro study

In vitro photoinactivation effectiveness of a portable LED device aimed for intranasal photodisinfection and a photosensitizer formulation comprising methylene blue and potassium iodide against bacterial, fungal, and viral respiratory pathogens

Intense pulsed light therapy for ocular surface diseases

Awake endoscopic laser surgery for early glottic carcinoma